Neomonachus schauinslandi (Hawaiian monk seal): 110591392
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Entry
110591392 CDS
T08474
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu01522
Endocrine resistance
nsu04010
MAPK signaling pathway
nsu04012
ErbB signaling pathway
nsu04014
Ras signaling pathway
nsu04024
cAMP signaling pathway
nsu04068
FoxO signaling pathway
nsu04071
Sphingolipid signaling pathway
nsu04137
Mitophagy - animal
nsu04140
Autophagy - animal
nsu04141
Protein processing in endoplasmic reticulum
nsu04210
Apoptosis
nsu04215
Apoptosis - multiple species
nsu04217
Necroptosis
nsu04310
Wnt signaling pathway
nsu04380
Osteoclast differentiation
nsu04510
Focal adhesion
nsu04530
Tight junction
nsu04620
Toll-like receptor signaling pathway
nsu04621
NOD-like receptor signaling pathway
nsu04622
RIG-I-like receptor signaling pathway
nsu04625
C-type lectin receptor signaling pathway
nsu04657
IL-17 signaling pathway
nsu04658
Th1 and Th2 cell differentiation
nsu04659
Th17 cell differentiation
nsu04660
T cell receptor signaling pathway
nsu04664
Fc epsilon RI signaling pathway
nsu04668
TNF signaling pathway
nsu04722
Neurotrophin signaling pathway
nsu04723
Retrograde endocannabinoid signaling
nsu04728
Dopaminergic synapse
nsu04750
Inflammatory mediator regulation of TRP channels
nsu04910
Insulin signaling pathway
nsu04912
GnRH signaling pathway
nsu04914
Progesterone-mediated oocyte maturation
nsu04917
Prolactin signaling pathway
nsu04920
Adipocytokine signaling pathway
nsu04926
Relaxin signaling pathway
nsu04930
Type II diabetes mellitus
nsu04931
Insulin resistance
nsu04932
Non-alcoholic fatty liver disease
nsu04933
AGE-RAGE signaling pathway in diabetic complications
nsu04935
Growth hormone synthesis, secretion and action
nsu04936
Alcoholic liver disease
nsu05010
Alzheimer disease
nsu05012
Parkinson disease
nsu05016
Huntington disease
nsu05017
Spinocerebellar ataxia
nsu05020
Prion disease
nsu05022
Pathways of neurodegeneration - multiple diseases
nsu05132
Salmonella infection
nsu05133
Pertussis
nsu05135
Yersinia infection
nsu05142
Chagas disease
nsu05145
Toxoplasmosis
nsu05152
Tuberculosis
nsu05161
Hepatitis B
nsu05162
Measles
nsu05166
Human T-cell leukemia virus 1 infection
nsu05167
Kaposi sarcoma-associated herpesvirus infection
nsu05169
Epstein-Barr virus infection
nsu05170
Human immunodeficiency virus 1 infection
nsu05171
Coronavirus disease - COVID-19
nsu05200
Pathways in cancer
nsu05208
Chemical carcinogenesis - reactive oxygen species
nsu05210
Colorectal cancer
nsu05212
Pancreatic cancer
nsu05231
Choline metabolism in cancer
nsu05415
Diabetic cardiomyopathy
nsu05417
Lipid and atherosclerosis
nsu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
110591392 (MAPK10)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110591392 (MAPK10)
04012 ErbB signaling pathway
110591392 (MAPK10)
04014 Ras signaling pathway
110591392 (MAPK10)
04310 Wnt signaling pathway
110591392 (MAPK10)
04668 TNF signaling pathway
110591392 (MAPK10)
04068 FoxO signaling pathway
110591392 (MAPK10)
04071 Sphingolipid signaling pathway
110591392 (MAPK10)
04024 cAMP signaling pathway
110591392 (MAPK10)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110591392 (MAPK10)
04137 Mitophagy - animal
110591392 (MAPK10)
09143 Cell growth and death
04210 Apoptosis
110591392 (MAPK10)
04215 Apoptosis - multiple species
110591392 (MAPK10)
04217 Necroptosis
110591392 (MAPK10)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110591392 (MAPK10)
04530 Tight junction
110591392 (MAPK10)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
110591392 (MAPK10)
04621 NOD-like receptor signaling pathway
110591392 (MAPK10)
04622 RIG-I-like receptor signaling pathway
110591392 (MAPK10)
04625 C-type lectin receptor signaling pathway
110591392 (MAPK10)
04660 T cell receptor signaling pathway
110591392 (MAPK10)
04658 Th1 and Th2 cell differentiation
110591392 (MAPK10)
04659 Th17 cell differentiation
110591392 (MAPK10)
04657 IL-17 signaling pathway
110591392 (MAPK10)
04664 Fc epsilon RI signaling pathway
110591392 (MAPK10)
09152 Endocrine system
04910 Insulin signaling pathway
110591392 (MAPK10)
04920 Adipocytokine signaling pathway
110591392 (MAPK10)
04912 GnRH signaling pathway
110591392 (MAPK10)
04914 Progesterone-mediated oocyte maturation
110591392 (MAPK10)
04917 Prolactin signaling pathway
110591392 (MAPK10)
04926 Relaxin signaling pathway
110591392 (MAPK10)
04935 Growth hormone synthesis, secretion and action
110591392 (MAPK10)
09156 Nervous system
04728 Dopaminergic synapse
110591392 (MAPK10)
04723 Retrograde endocannabinoid signaling
110591392 (MAPK10)
04722 Neurotrophin signaling pathway
110591392 (MAPK10)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
110591392 (MAPK10)
09158 Development and regeneration
04380 Osteoclast differentiation
110591392 (MAPK10)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110591392 (MAPK10)
05208 Chemical carcinogenesis - reactive oxygen species
110591392 (MAPK10)
05231 Choline metabolism in cancer
110591392 (MAPK10)
09162 Cancer: specific types
05210 Colorectal cancer
110591392 (MAPK10)
05212 Pancreatic cancer
110591392 (MAPK10)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
110591392 (MAPK10)
05170 Human immunodeficiency virus 1 infection
110591392 (MAPK10)
05161 Hepatitis B
110591392 (MAPK10)
05171 Coronavirus disease - COVID-19
110591392 (MAPK10)
05162 Measles
110591392 (MAPK10)
05167 Kaposi sarcoma-associated herpesvirus infection
110591392 (MAPK10)
05169 Epstein-Barr virus infection
110591392 (MAPK10)
09171 Infectious disease: bacterial
05132 Salmonella infection
110591392 (MAPK10)
05135 Yersinia infection
110591392 (MAPK10)
05133 Pertussis
110591392 (MAPK10)
05152 Tuberculosis
110591392 (MAPK10)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110591392 (MAPK10)
05142 Chagas disease
110591392 (MAPK10)
09164 Neurodegenerative disease
05010 Alzheimer disease
110591392 (MAPK10)
05012 Parkinson disease
110591392 (MAPK10)
05016 Huntington disease
110591392 (MAPK10)
05017 Spinocerebellar ataxia
110591392 (MAPK10)
05020 Prion disease
110591392 (MAPK10)
05022 Pathways of neurodegeneration - multiple diseases
110591392 (MAPK10)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110591392 (MAPK10)
05418 Fluid shear stress and atherosclerosis
110591392 (MAPK10)
05415 Diabetic cardiomyopathy
110591392 (MAPK10)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
110591392 (MAPK10)
04936 Alcoholic liver disease
110591392 (MAPK10)
04932 Non-alcoholic fatty liver disease
110591392 (MAPK10)
04931 Insulin resistance
110591392 (MAPK10)
04933 AGE-RAGE signaling pathway in diabetic complications
110591392 (MAPK10)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
110591392 (MAPK10)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110591392 (MAPK10)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
110591392 (MAPK10)
Protein kinases [BR:
nsu01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
110591392 (MAPK10)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
ABC1
RIO1
Kinase-like
APH
FTA2
Motif
Other DBs
NCBI-GeneID:
110591392
NCBI-ProteinID:
XP_044768615
UniProt:
A0A8M1M6H9
LinkDB
All DBs
Position
2:133857082..134181246
Genome browser
AA seq
464 aa
AA seq
DB search
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgagcctccatttattgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccaattctatagtgtggaagtcggagactcaaccttcacagtt
ctcaagcgctaccagaatttgaagcctattggctctggggctcagggaatagtttgtgct
gcgtatgatgctgttcttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacgcatgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacattggaggaattccaa
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgaacgaatgtcttacctgctataccaaatgttgtgtggcatcaagcacctt
cactctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaagtctgat
tgtacattgaaaatcctcgactttggactagccaggacggcaggcacaagcttcatgatg
actccttatgtggtcacacgttattatagagcccccgaggttattctgggaatgggctac
aaggagaatgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaagtaattgagcaactagga
acaccatgtccggaattcatgaagaaattgcaacctacagtaagaaactatgtggagaat
cggcccaagtatgcaggactcaccttccccaagctctttccagattccctcttcccagcg
gactctgagcacaataaactcaaagccagccaagccagggacttactgtcaaagatgcta
gtgattgacccagcaaaaaggatatctgtggatgacgccttacagcatccttacatcaat
gtgtggtacgaccctgccgaagtggaggcgcctccacctcagatttatgacaaacagttg
gacgaaagagaacacaccattgaagaatggaaagaacttatctacaaagaagtaatgaat
tctgaagaaaagactaaaaacggtgttgtaaaaggacaaccttctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcttcgtccgtcaatgacatctcttccatgtcc
actgaccagaccctggcatccgacactgacagcagcctggaagcctcagcaggacccctg
ggttgttgcaggtga
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