Neomonachus schauinslandi (Hawaiian monk seal): 110591430
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Entry
110591430 CDS
T08474
Symbol
HPSE
Name
(RefSeq) heparanase isoform X1
KO
K07964
heparanase [EC:
3.2.1.166
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00531
Glycosaminoglycan degradation
nsu01100
Metabolic pathways
nsu05205
Proteoglycans in cancer
Module
nsu_M00078
Heparan sulfate degradation
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00531 Glycosaminoglycan degradation
110591430 (HPSE)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
110591430 (HPSE)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
00536 Glycosaminoglycan binding proteins [BR:
nsu00536
]
110591430 (HPSE)
Enzymes [BR:
nsu01000
]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.166 heparanase
110591430 (HPSE)
Glycosaminoglycan binding proteins [BR:
nsu00536
]
Heparan sulfate / Heparin
Enzymes
110591430 (HPSE)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glyco_hydro_79n
Motif
Other DBs
NCBI-GeneID:
110591430
NCBI-ProteinID:
XP_021558009
UniProt:
A0A2Y9I6Y0
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Position
2:136577676..136614011
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AA seq
540 aa
AA seq
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MPLRWKPGLPLLLLLGPLGPFSPGARAGPAQAEDAVELRFSTERPVHLVSPAFLSFTIDA
NLATDPRFLTFLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPQKEPTFEERSYWQSQVN
QDMCKSGSIPSDVEKRLQLEWPFQEQLLLREQYQKKFKNSTYSKSSVDMLYTFANCSGLD
LIFGLNALLRSADLQWNSSNAQLLLDYCSSKNYNISWELGNEPNSFRKKAGIFIDGLQLG
EDFVKLHKLLGKTTFKTANLYGPDVGQPRGKTLKILRSFLKAGGEVIDSLTWHHYYLNGR
IATKEDFLNPDVLDTFTSSVQKIFQVVEETRPDKKVWLGETSSAYGGGAPLLSNTFAAGF
MWLDKLGLSARMGIEVVMRQVLFGAGNYHLVDENFKPLPDYWLSLLFKKLVGTRVFMASV
KGPDGRKLRVYLHCTNVNHPRYKEGDLTLYALNLHNVTKRLRLPYHLFDKQVDKYLIKPL
GPDGLLSKSVQLNGQTLKMVDDHTLPALTEKALRPGSSLGLPAFSYGFFVIKNAKVTACL
NT seq
1623 nt
NT seq
+upstream
nt +downstream
nt
atgccgctgcgctggaagccggggctgccgctgctgctgctcctggggccgctcggtccc
ttctcccccggcgcccgggcgggacccgcgcaggccgaggacgctgtggagctgcgcttc
tccaccgagcgtccggtgcacctggtgagtcccgcgttcctgtccttcaccatcgacgcc
aacctggccaccgacccgcggttcctcaccttcctgggttctccaaagcttcgcactttg
gctagaggtttgtctccggcatacctgcgatttggtggcaccaagacggactttctcatt
ttcgatccccaaaaagaaccgacctttgaagagaggagttactggcagtctcaagtcaac
caggatatgtgcaaatctggatccatcccttctgatgtagagaagaggttacagttggaa
tggcccttccaggaacaattgctgctcagagaacagtatcagaaaaagttcaagaacagc
acttactcaaaaagctccgtggatatgctgtatacttttgcaaattgctcaggactggac
ttgatctttgggctaaatgccttactacgatcagcagatttgcagtggaacagttctaac
gctcagttgctcctggactattgctcttccaagaattataacatttcttgggaactaggc
aatgaacctaacagtttccgtaagaaggctggtattttcatcgatggattgcagttagga
gaagattttgtcaagttgcataaacttctaggaaaaaccactttcaaaactgcgaatctc
tatggtcctgatgttggccagcctcgaggaaagactctcaagatactgagaagtttcctg
aaggctgggggtgaagtgattgattcacttacatggcaccactactacttgaatggacga
attgctaccaaagaagatttcctaaaccctgatgtgctggacacttttacttcatctgtg
caaaaaatttttcaggttgtcgaggagaccagacccgacaagaaggtttggttaggagaa
acgagctctgcgtatgggggtggagcacccttgctgtccaacacctttgcggctggcttt
atgtggctggataaattgggcctatcggccagaatgggcatagaagtggtgatgaggcaa
gtgctcttcggagccggaaactaccacttagtggatgaaaacttcaaacctctacctgat
tactggctatctcttctgttcaagaaattggtgggcacccgtgtgtttatggcaagtgtg
aaaggtccagacggaagaaaactccgagtgtaccttcattgtacgaacgtcaaccaccca
aggtataaagaaggagatctaactttgtacgccttaaacctccataacgtcacaaaacgc
ctgcggttgccctatcatctgtttgacaaacaagtggacaaatacctcataaaaccttta
gggcctgatggattactttccaaatccgtccagctcaatggtcaaactctgaagatggtg
gatgatcacaccctcccggctttgacagaaaaagctctccgcccaggaagttctctgggc
ttgccagcgttctcatatggattttttgtgataaaaaatgctaaagttactgcttgcctc
tga
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