KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110591803
Entry
110591803         CDS       T08474                                 
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1
  KO
K03934  NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00190  Oxidative phosphorylation
nsu01100  Metabolic pathways
nsu04714  Thermogenesis
nsu04723  Retrograde endocannabinoid signaling
nsu04932  Non-alcoholic fatty liver disease
nsu05010  Alzheimer disease
nsu05012  Parkinson disease
nsu05014  Amyotrophic lateral sclerosis
nsu05016  Huntington disease
nsu05020  Prion disease
nsu05022  Pathways of neurodegeneration - multiple diseases
nsu05208  Chemical carcinogenesis - reactive oxygen species
nsu05415  Diabetic cardiomyopathy
Module
nsu_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    110591803 (NDUFS1)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    110591803 (NDUFS1)
  09159 Environmental adaptation
   04714 Thermogenesis
    110591803 (NDUFS1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    110591803 (NDUFS1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    110591803 (NDUFS1)
   05012 Parkinson disease
    110591803 (NDUFS1)
   05014 Amyotrophic lateral sclerosis
    110591803 (NDUFS1)
   05016 Huntington disease
    110591803 (NDUFS1)
   05020 Prion disease
    110591803 (NDUFS1)
   05022 Pathways of neurodegeneration - multiple diseases
    110591803 (NDUFS1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    110591803 (NDUFS1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    110591803 (NDUFS1)
Enzymes [BR:nsu01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     110591803 (NDUFS1)
SSDB
Motif
Pfam: Molybdopterin Fer4_Nqo3 Fer4_NDSU1 Fer2_4 NADH_dhqG_C NADH-G_4Fe-4S_3 Fer2 ACR_tran
Other DBs
NCBI-GeneID: 110591803
NCBI-ProteinID: XP_021558394
UniProt: A0A2Y9IA76
LinkDB
Position
3:complement(163642454..163671221)
AA seq 735 aa
MLRIPLKRALVGLSKSSKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFL
LANHPLDCPICDQGGECDLQINSPNLLKDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTI
MTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALT
SKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRF
AYDGLKRQRLTEPMVRNEKGLLTYTSWEDALSCVAGMLQSFQGNDVAAIAGGLVDAEALI
ALKDLLNRVDSDTLCTEEVFPTTGAGTDLRSSYLLNTTIAGVEEADVVLLVGTNPRFEAP
LFNARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIAFGSHPFSQVLHEAKKP
MVVVGSSALQRSDGAAILAAVSNIAQKIQMSSGVTRDWKVMNILHRIASQVAALDLGYKP
GVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEK
SATYVNTEGRAQQTKVAVTPPGLAREDWKILRALSEIAGMTLPYDTLDQVRNRLEEVSPN
LVRYDDVEGANYFQQANELSKLVNQQLLADPLIPPQLTIKDFYMTDSISRASQTMAKCVK
AVTEGAQAVEEPSIC
NT seq 2208 nt   +upstreamnt  +downstreamnt
atgttaaggatacctctaaaaagggccttagtaggcctttctaagtcttctaaaggatgt
gttcgaacaactgccacagcagcaagcaacttaattgaagtatttgttgatggtcagtct
gtcatggtggaaccaggaactaccgtccttcaagcttgtgagaaggttggcatgcagatc
cctcgattctgttaccatgaaagattgtctgttgctggaaactgcaggatgtgcctggtt
gaaattgagaaagctcctaaggttgtagctgcttgtgccatgccagtaatgaaaggttgg
aatatcctgacaaactcagagaaatctaagaaagccagagaaggtgtgatggagttcttg
ttagcaaatcacccactggactgtcctatttgtgaccagggaggtgaatgtgatctgcag
attaactctcctaatctacttaaggaccagtccatgatgttcggaagtgataggagccga
tttttagaggggaaacgtgctgtggaggacaagaatattgggccattggtaaagaccatc
atgactagatgtatacaatgtactcgctgcatcaggtttgcaagtgagattgcaggagta
gatgatttgggaacaacaggcagaggaaatgatatgcaagttggcacgtacattgaaaag
atgttcatgtctgaactgtctggaaatatcattgatatctgccctgtaggtgccctgacc
tctaagccctatgcttttactgcccgcccttgggaaacaagaaagacagaatccattgat
gtcatggatgcggttggaagtaatattgtggtaagcacaagaacaggagaggtgatgagg
attttaccaaggatgcatgaggacatcaatgaagagtggatctctgataaaaccagattt
gcctatgatgggctaaaacgtcaaagacttaccgagccgatggtcagaaacgaaaagggg
cttttaacctatacctcctgggaggatgcactctcttgtgtagctggaatgttgcagagt
tttcaaggcaatgatgtggcagcaattgcaggtggcttggtggatgccgaagccctaata
gctctcaaagatttgcttaatagagtggactctgacaccttgtgcacggaagaggtcttc
cccactacaggagctggcacagatttgcgttccagttatcttcttaatactacaattgct
ggtgtggaagaggcagatgttgtccttctggttggtacaaatccacgttttgaggcacca
ctatttaatgctagaattcgaaagagctggcttcacaatgacttaaaagtggcccttatt
ggcagcccagtggatctcacttatagatatgaccatctgggagattctcccaaaattctt
caagacattgctttcggtagccatccattcagccaggtattacatgaagctaaaaaacca
atggtggttgtaggcagttctgcactccagagaagtgatggggcagcaattcttgcagct
gtttccaacattgctcaaaagattcagatgagtagtggtgttactcgtgattggaaagtt
atgaatatccttcataggattgcaagccaggtagctgctttggatcttgggtataaacct
ggggtggaagcaattcgtaagaaccctcccaaagtgctgtttctcctgggagcagatgga
ggttgtatcactcgacaggatttgccaaaggattgtttcattatttatcaaggacatcat
ggtgacgttggcgctcctatagctgatgttattctcccaggcgctgcttacacagagaaa
tctgctacttatgtcaatactgagggccgagctcagcagactaaagtagcagtgacacct
cctggcttggcaagagaagactggaaaattctaagagccctctctgagattgcaggtatg
actcttccatatgatactctggatcaagtaaggaacagattggaagaagtctctcctaat
cttgtccgatatgatgatgtcgaaggagccaattatttccagcaagcaaatgagctctct
aagctagtgaaccaacagcttcttgctgatccacttattccacctcagctaacaataaaa
gacttctacatgacagactcaattagcagagcttcacagacaatggccaaatgtgtcaaa
gctgtcacggagggtgcccaggcagtagaggaaccatccatatgctga

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