Neomonachus schauinslandi (Hawaiian monk seal): 110593180
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Entry
110593180 CDS
T08474
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X5
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu01521
EGFR tyrosine kinase inhibitor resistance
nsu01522
Endocrine resistance
nsu01524
Platinum drug resistance
nsu04010
MAPK signaling pathway
nsu04012
ErbB signaling pathway
nsu04020
Calcium signaling pathway
nsu04066
HIF-1 signaling pathway
nsu04151
PI3K-Akt signaling pathway
nsu04510
Focal adhesion
nsu04520
Adherens junction
nsu04530
Tight junction
nsu05200
Pathways in cancer
nsu05205
Proteoglycans in cancer
nsu05206
MicroRNAs in cancer
nsu05212
Pancreatic cancer
nsu05213
Endometrial cancer
nsu05215
Prostate cancer
nsu05219
Bladder cancer
nsu05223
Non-small cell lung cancer
nsu05224
Breast cancer
nsu05226
Gastric cancer
nsu05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110593180 (ERBB2)
04012 ErbB signaling pathway
110593180 (ERBB2)
04066 HIF-1 signaling pathway
110593180 (ERBB2)
04020 Calcium signaling pathway
110593180 (ERBB2)
04151 PI3K-Akt signaling pathway
110593180 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
110593180 (ERBB2)
04520 Adherens junction
110593180 (ERBB2)
04530 Tight junction
110593180 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110593180 (ERBB2)
05206 MicroRNAs in cancer
110593180 (ERBB2)
05205 Proteoglycans in cancer
110593180 (ERBB2)
05230 Central carbon metabolism in cancer
110593180 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
110593180 (ERBB2)
05226 Gastric cancer
110593180 (ERBB2)
05219 Bladder cancer
110593180 (ERBB2)
05215 Prostate cancer
110593180 (ERBB2)
05213 Endometrial cancer
110593180 (ERBB2)
05224 Breast cancer
110593180 (ERBB2)
05223 Non-small cell lung cancer
110593180 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110593180 (ERBB2)
01524 Platinum drug resistance
110593180 (ERBB2)
01522 Endocrine resistance
110593180 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110593180 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
nsu04147
]
110593180 (ERBB2)
04090 CD molecules [BR:
nsu04090
]
110593180 (ERBB2)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110593180 (ERBB2)
Protein kinases [BR:
nsu01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
110593180 (ERBB2)
Exosome [BR:
nsu04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
110593180 (ERBB2)
CD molecules [BR:
nsu04090
]
Proteins
110593180 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
110593180
NCBI-ProteinID:
XP_021560093
UniProt:
A0A2Y9I878
LinkDB
All DBs
Position
15:38210903..38234835
Genome browser
AA seq
1260 aa
AA seq
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MELAAWCRWGLLLALLPSGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQACQVVQGNL
ELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
EPPEGGASEAGAAPGGLRELQLRGLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LMLIDTNRSRACPPCSPACKDPHCWGASSGDCQSLTRTVCAGGCARCKGPKPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKVFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEELTGYLYISAWPDSLP
NLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNARLCFIHTV
PWDQLFRNPHQALLHSANRPEAECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHSECRPQNGSVTCFGAEADQCVACAHYKDPPFCVARC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDERGCPAEQRASPVTSIIAAVVG
ILLAVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGPAHHRHRSSSTRSGGGEVSQGLEPSEEEPPKSPLAPSDG
AGSDVFDGDLGMGAAKGLHSLPPQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVWPQPPSPLEGSLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGSAVENPE
YLAPRGRAPPQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccctccggagcc
gcgggcacccaagtgtgtaccggcacagacatgaagctgcggctcccagccagtcccgag
acgcacctggatatgctccgtcacctctaccaggcctgtcaagtggtgcagggtaacctg
gagctcacctacctgcctgccaatgccagcctgtccttcctgcaggatatccaggaggtg
cagggctacgtgctcattgctcacagccaagtgagacaggtcccgctgcagaggctccga
atcgtgcgaggcacccagctctttgaggacaactacgccctggccgtgctggacaatgga
gagccgcccgaggggggcgcctctgaggcaggggctgccccaggagggctgcgggagctg
cagcttcgaggcctcacagagatcctgaagggaggggtcttgattcagcggaacccacag
ctctgccaccaggacacgattttgtggaaggacatcttccacaagaacaaccagcttgcg
ctcatgctgatagacaccaaccgctctcgggcctgcccaccctgttctccagcttgtaaa
gacccccactgctggggagcaagttctggggactgtcagagcttgacgcgaacggtctgt
gccggaggctgtgcccgctgcaagggcccgaagcccactgactgctgccacgagcagtgt
gcagcgggttgcacgggccccaagcactcggactgcctggcctgccttcacttcaaccac
agtggtatctgtgagctgcactgcccagccctggtcacctacaacacggacaccttcgaa
tccatgcccaaccccgagggccgatacaccttcggggccagctgtgtgaccgcctgtcca
tacaactacctatctacggacgtgggctcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacggctgaggacggaacacagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctacggcctgggcatggagcacctgcgggaggtgagggcggtcaccagcgccaac
atccaagagtttgccggctgcaagaaggtctttgggagcctggcgtttctgccagagagc
tttgagggagacccagcctccaacactgcccccctccagcctgagcagctcagagtgttt
gaggctctggaggagctcacaggttacctgtatatctcagcgtggccagacagcctgcct
aacctcagtgtcttccagaacctgcgagtcatccggggacgagttctgcatgacggcgcc
tactcgctgaccctgcaagggctgggcatcagctggctggggctgcgctcactgcgggaa
ctgggcagtgggctggccctcatccaccgcaacgcccgcctctgcttcatacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctgcacagtgccaaccggccg
gaggccgagtgtgtgggcgagggcctggcctgctacccgctgtgcgcccatgggcactgc
tggggtccggggcccacccagtgcgtcaactgcagccaattccttcggggccaggagtgc
gtggaggaatgccgagtactgcaggggctaccccgggaatatgtgaaggacaggtactgt
ctgccgtgtcactccgagtgtcggccccagaacggctcagtgacctgctttggggcggag
gctgaccagtgtgtggcctgtgcccactacaaggaccctcccttctgcgtggctcgctgc
cccagtggtgtgaaacccgacctctccttcatgcccatttggaagttcgcagatgaggag
ggcacgtgccagccgtgtcccatcaactgcacccactcctgtgcggacctagacgagagg
ggctgccctgccgagcagagagccagccccgtgacatccatcattgctgctgtggtgggc
attctgctggctgtggtcgtggggctggtcctcggcatcctaatcaagcgaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggaaaccgagctggtggagccgctg
acgcctagcggagcgatgcccaaccaggctcagatgcggatcctgaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcacagtctacaagggcatctggatc
cctgatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggatgaagcatatgtgatggctggcgtgggctcccca
tatgtgtcccgccttctgggcatctgcctgacatccacggtgcagctggtaacacagctc
atgccctacggctgcctcttagaccatgtccgagagcaccgcggacgcctaggctcccag
gacctgctgaactggtgtgtgcagatcgccaaggggatgagctacttggaggacgttcgg
ctcgtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccatgtcaag
attacagacttcgggctggctcggttgctggacattgacgagaccgagtaccacgcggat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
caccagagcgatgtgtggagctacggtgtgactgtgtgggaactgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggagaagggggagcgg
ctgccccagccccccatctgcaccattgacgtctacatgatcatggtcaaatgttggatg
atagactccgaatgtcgaccacggttccgggagctggtggccgaattctcccgcatggcc
agggacccccagcgctttgtggttatccagaatgaagacttgggccccgccagcccgttg
gacagcaccttctaccgttcgctgctggaagatgatgacatgggggacctggtggatgct
gaggagtacctggtaccccagcaggggtttttctgtccagaccctgccccaggtgctggg
ggcccggcccaccacaggcaccgcagctcatccaccaggagtggcggtggtgaggtgtca
cagggactggagccctccgaggaggagccccccaagtctccactggcaccctcagacggg
gctggctctgacgtgtttgatggcgacttgggaatgggggcagccaaggggctgcacagc
cttccgccacaggaccccagtcctctacagcggtacagcgaggaccctacagtacccctg
ccccctgagactgatggctacgttgcccccctgacctgcagcccccagcctgaatatgtg
aatcagccagaggtttggccgcagcccccctcgcccctagaaggctctctgcctccttct
cgacctgccggtgccactctggaaaggcccaagactttgtcccccaagactctctcccct
ggcaagaatggggttgttaaagacgtttttgcctttgggagtgctgtggagaaccctgag
tacttggcaccccggggcagggctccccctcagccccaccctcctccagccttcagccca
gcatttgacaacctctattactgggaccaggacccatcagagcggggctctccacccagc
acctttgaagggacccctacagcagaaaaccctgagtacctgggcctggacgtgccagtg
tga
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