Neomonachus schauinslandi (Hawaiian monk seal): 110593684
Help
Entry
110593684 CDS
T08474
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X3
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04217
Necroptosis
nsu04380
Osteoclast differentiation
nsu04620
Toll-like receptor signaling pathway
nsu04621
NOD-like receptor signaling pathway
nsu04630
JAK-STAT signaling pathway
nsu04658
Th1 and Th2 cell differentiation
nsu04659
Th17 cell differentiation
nsu05145
Toxoplasmosis
nsu05160
Hepatitis C
nsu05161
Hepatitis B
nsu05162
Measles
nsu05164
Influenza A
nsu05165
Human papillomavirus infection
nsu05167
Kaposi sarcoma-associated herpesvirus infection
nsu05168
Herpes simplex virus 1 infection
nsu05169
Epstein-Barr virus infection
nsu05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
110593684 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
110593684 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
110593684 (TYK2)
04621 NOD-like receptor signaling pathway
110593684 (TYK2)
04658 Th1 and Th2 cell differentiation
110593684 (TYK2)
04659 Th17 cell differentiation
110593684 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
110593684 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
110593684 (TYK2)
05160 Hepatitis C
110593684 (TYK2)
05171 Coronavirus disease - COVID-19
110593684 (TYK2)
05164 Influenza A
110593684 (TYK2)
05162 Measles
110593684 (TYK2)
05168 Herpes simplex virus 1 infection
110593684 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
110593684 (TYK2)
05169 Epstein-Barr virus infection
110593684 (TYK2)
05165 Human papillomavirus infection
110593684 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110593684 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110593684 (TYK2)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
110593684 (TYK2)
Protein kinases [BR:
nsu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
110593684 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
FERM_C_FAK1
APH
RA_2
ABC1
Motif
Other DBs
NCBI-GeneID:
110593684
NCBI-ProteinID:
XP_021560653
UniProt:
A0A2Y9I9Q1
LinkDB
All DBs
Position
1:207195276..207215467
Genome browser
AA seq
1189 aa
AA seq
DB search
MPLCHWGATTRDSKPDGDGAQPMATKGGLKVLLHWAGPGGGDPWVTFSEATLTAEEVCIH
IAQKVGITPSCLNLFALFDAQAQVWLPPNHVLEISRDMSLTLYFRMRFYFRNWHGTNPQE
PAIYRCGPPGPKSSSEQAEQGMQLLDPASFEYLFEQGKHEFVNDVASLSELSSEEEIHHF
KNESLGMAFLHLCHLALYHGIPLGKVAKKISFKDCIPRSFRLQIQQHNALTRLRLRNIFR
RFVRAFQPGHVSQQVIMVKYLAMLELLAPRFGTECLPVCHLELLAQAVGEPYYIQDGGQA
PPEPGPELATGPPTHEVLVTGTGGIQWRPIQAEGPRGDGSSRNPRAGPFGKKTKAPEVGG
QPADRPQEAPWAYFCDFQDITHVVLKECHVSIRCQDNKSLELTLPSRAMALSLVSLVDGY
FRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVLAKLRPEDGLYLIHWSTSRLNRL
ILTVAQREQAPGTQHVHLRKFPIELQAGGFTLEGWDRSFPSVWELRAALQGCSLRAGDDC
FSLHHCCLPRPGEISNLIIMRGSRASTGPPNLSQLSFHRICQDDITQLSHLGQGTRTNVY
EGILRVGGRGPKEGTADGEDPPTPGGDCGQELRVVLKVLDPSHHNIALAFYETASLMSQV
SHVHLAFVHGICVHGSENIMVTEYVEHGPLDVWLRREKGHVPVAWKVAVAQQLASALSYL
EDKSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWTAPECLS
GGANSLTTAADKWGFGATLLEICFDGEAPLQGRGPSEKEYFYQKQLRLPQPSCPELATLT
SQCLTYEPAQRPSFRTILRDLTQLQPQNLADVLAVNPDSPTSDPTIFHKRYLKKIRDLGE
GHFGKVCLYCYDPTNDGTGEMVAVKALKADCGPQLRTGWRREIDILRTLYHKHIVKYKGC
CEDPGEKSVQLVMEYVPLGSLRDYLPRHSVGLVQLLLFAQQICEGMAYLHAQHYVHRDLA
ARNVLLDNDRLVKIGDFGLAKAVPEGHDYYRVREDGDSPVFWYAPECLKECKFYYASDVW
SFGVTMYELLTYCDSNQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPERCPCESH
FFPAQIYLLMKNCWEADASFRPTFQNLIPILKTVQEKYQGQAASVFSVC
NT seq
3570 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccattggggtgccaccaccagggacagcaagcctgatggagatggagct
cagcccatggccaccaagggaggcctgaaggtccttctgcactgggctggccctggcggc
ggggacccctgggtcaccttcagcgaggccacactgactgcagaggaggtctgcatccac
attgcacaaaaagtcggcatcactccgtcctgcctcaatctctttgctctgttcgatgcc
caggctcaggtctggctgcccccaaaccacgtcttggagatctccagagacatgagcctg
acattgtacttccgcatgaggttttatttccggaactggcatggcacgaatcctcaggag
ccggctatataccgctgtggacccccagggcccaagtcttcctcagaacaggcagagcag
gggatgcaactgctggacccagcctcctttgagtacctctttgagcagggcaagcatgag
tttgtgaatgacgtggcatcactatcggagctctcgagcgaggaggagatccaccatttt
aagaatgagagtctgggcatggccttcctgcatctctgccaccttgctctctaccatggc
atccccctggggaaggtggccaagaagatcagcttcaaggactgcatcccacgctccttc
cggctgcagatccagcagcacaacgcgctcacgcggctgcgcctgcggaacatcttccgc
aggttcgtgcgggccttccagccaggccacgtgtcgcagcaggtcatcatggtcaaatac
ctggccatgctcgagctgctggcaccccgcttcggcaccgagtgcctgcccgtgtgccac
ctggagctgctggcccaggccgtcggggagccctactacatccaggacggcgggcaggct
cccccagagcctgggccggagttggccactgggccccccactcatgaggtgctggtgacg
ggcacgggtggcatccagtggcggccgatacaggcagagggtcccagaggcgacggcagc
agcaggaatccccgtgctggcccatttgggaagaaaaccaaggccccggaggtgggcggt
cagcccgcggacaggcctcaggaagcgccctgggcctacttctgtgacttccaggatatc
acgcacgtggtgctgaaggaatgccacgtcagcatccgctgtcaggacaacaagagcctg
gagctgaccctgccttcccgggccatggccctgtccttggtgtcgctggtggacggctat
ttccgcctgaccgccgactcgagccactacctgtgccacgaggtggctccaccacggcta
gtgatgagcatccgggacggtatccacggacctctgctggagccgtttgtgctggccaag
ctgcggcctgaggatggcctctacctcatccattggagcaccagccgcctcaaccgcctc
atcctcacggtggcccagcgtgagcaggccccgggcacacagcacgtgcacctgcgtaaa
ttccccattgagctgcaggccgggggcttcacgctggagggttgggaccggtccttcccc
agcgtgtgggagctgcgggctgccctccagggttgctccctgcgggctggtgatgactgt
ttctccctgcaccactgctgcctgcctcggccgggagagatctccaacctcatcatcatg
cgggggtctcgggccagcactggtccgcccaacctcagccagctcagcttccaccggatc
tgccaggatgacatcacccagctgtcccacttgggccaaggcacgaggaccaatgtgtat
gagggcatcttacgagtggggggcagaggccccaaggagggcacggccgatggtgaggac
ccccctacgcccggtggggactgtgggcaagagctccgagtggtactcaaggtgctggac
cccagtcaccacaacatcgccctggccttctacgagacagccagcctcatgagccaggtc
tcccacgtgcacctggcctttgtacacggcatctgcgtgcacggctctgagaacatcatg
gtaacagagtacgtggagcacgggcccctggacgtgtggctgcggcgggagaagggccac
gtgcctgtggcctggaaggtggccgtggcccagcagctggccagcgccctcagctacctg
gaagacaagagcctggttcatggtaatgtgtgtggccggaacatcctgctggcgaggctg
ggactggcagagggcaccagccccttcatcaagctgagcgaccctggtgtgggcctgggc
gccctttctagggaggagcgggtggagcggatcccctggacagcccccgagtgcctatct
ggcggagccaacagcctaaccactgcagccgataaatggggctttggtgccaccctcctg
gagatctgctttgacggggaggcccctctgcagggccgtggcccttccgagaaagagtac
ttctaccagaagcagctccggcttcctcagccctcctgcccggagctggccacactcacc
agccagtgcctgacctatgaaccagctcagcggccctccttccgcaccatcctgcgtgac
ctcactcagctgcagccccaaaatcttgctgacgtcttggctgtgaaccccgactcgcct
acgtcagaccccaccattttccacaagcgctatttgaaaaagatccgggatctgggcgag
ggtcatttcggcaaggtctgcctgtattgctacgaccccacgaatgacggcactggcgag
atggtggccgtgaaggccctcaaggcggactgcggcccccagctccgcaccggctggagg
cgggagatcgacatcctgcgcacgctctaccacaagcacatcgtcaagtacaagggctgc
tgcgaggacccaggcgagaagtcggtgcagctggtcatggagtacgtgcccctgggcagc
ctgcgggactacctgccccggcacagcgtgggcctggtgcagctgcttctcttcgcccag
cagatctgtgagggcatggcctaccttcacgcacagcactatgtgcaccgagacctggct
gcccgcaacgtgctcctggacaacgacaggctggtcaaaatcggggactttggcctagcc
aaggctgtgcctgaaggccatgactactaccgcgtgcgcgaagatggggacagccccgta
ttctggtatgccccagagtgcctgaaggagtgtaagttctactatgcatccgacgtctgg
tccttcggggtcaccatgtatgagctgctgacctactgtgactccaaccagagcccccca
tcgaaattcatcgagctcataggcctcacccaggggcagatgacggtgctgaggctcact
gaactgctggaacgaggggagaggctgccccggccagagagatgtccttgtgagtcccac
ttttttcctgcccagatctatctcctcatgaagaactgctgggaggcagacgcttcattc
cgccccaccttccagaacctcatacccattctcaagacagtccaggagaaataccaaggc
caggccgcctcagtgttcagtgtgtgctga
DBGET
integrated database retrieval system
