Neomonachus schauinslandi (Hawaiian monk seal): 110593718
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Entry
110593718 CDS
T08474
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00230
Purine metabolism
nsu01100
Metabolic pathways
nsu04024
cAMP signaling pathway
nsu04928
Parathyroid hormone synthesis, secretion and action
nsu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
110593718 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
110593718 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
110593718 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
110593718 (PDE4A)
Enzymes [BR:
nsu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
110593718 (PDE4A)
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Gene cluster
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Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
110593718
NCBI-ProteinID:
XP_021560721
UniProt:
A0A2Y9IAH8
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Position
1:complement(207127677..207170412)
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AA seq
871 aa
AA seq
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MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPARS
PHRPIERADAVDTGDRPGLRTSRMSWPSSFHGTGTGSGGASGGSCRRFEAENGPTPSPGR
SPLDSQASPGLVLHAGAAASQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRGVRSNFSLLTNVPIPSNRRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKDREKQSAPRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLNDSSIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYML
TLEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEDPRGPGHPPPPDKFQFELTLEEEEEED
VSTSPGAFEARHLSLAQDPSPAEELWEVDGQAMAAEVKVKEPRFTQQGDSADSVAAGEDE
SMSPDASVEAGGRSRPLALSAESPPLPALRTLPPPEEAPGLLGLPSMAAEVGAQKEHQAA
KRVCSACTGTSGEDPPPLPAPGGWGSAGGPT
NT seq
2616 nt
NT seq
+upstream
nt +downstream
nt
atggagcccccggccgccccctcggagaggagcctgtctctgtctctgcccgggccccgg
gagggccaggccaccctgaagccgcccccccagcacctgtggcggcagccgcggaccccc
attcgtatccagcagcgcggctactccgacagcgcggagcgcgcagagcccgcacggtcc
ccacaccggcccatagagcgtgccgacgccgtggacaccggcgaccggcccggcctgcgc
acttcccgcatgtcctggccctcgtccttccacggtaccggcaccggcagcggcggcgcg
agcggaggcagctgcaggcgcttcgaggcagagaatgggcccacaccatctcctggccgc
agccccctggactcgcaggcgagcccgggcctcgtgctgcatgctggggccgctgccagc
cagcgccgggagtccttcctgtaccgttcagacagcgactacgacatgtcccccaaaact
atgtcccggaactcgtcggtcaccagcgaggcgcacgctgaggacctcattgtgacacct
ttcgcccaggtgctggccagtctccggggtgttcgcagcaacttctcactcctgaccaat
gtgcccattcccagcaacagacggtccccgttgggcggcccaacccccgtctgcaaggcc
acgctgtcagaagagacatgtcagcaattggcccgggagacactggaggagctggactgg
tgtctcgaacagctggagaccatgcagacctaccgctccgtgagcgagatggcttcccac
aagttcaagaggatgttaaaccgtgaactcacacacctgtcagagatgagcaggtcagga
aaccaggtctctgagtacatctctaccacattcctggacaagcagaatgaagtggagatt
ccatcacccacaatgaaggatcgagaaaaacagtcagccccacggcagagaccctcccag
cagcccccgccccctgggccgcaattccagcccatgtctcagatcacaggggtgaagaag
ctgatgcacagcagcagcctgaatgattccagcatcccccgctttggggtgaagaccgac
caagaggagctcctggcccaagaactagagaacctgaacaagtggggtctgaacatcttt
tgcgtgtcagaatacgccggaggccgttccctcagctgcatcatgtacacgatatttcag
gagcgggacctgctgaagaagttccgcatcccggtggacaccatggtgacttatatgctg
accctggaggaccactaccaccccgacgtggcctaccacaacagcctgcacgcggctgac
gtgctgcagtccacgcatgtgctgttggccacacccgcgctcgatgctgtgttcacggac
ctggagattcttgccgccctcttcgcggctgccattcatgacgtggaccatcctggggtc
tccaaccagttcctgatcaacaccaattcggagctggcgctcatgtacaacgacgagtcc
gtgctggagaatcaccacctggccgtgggcttcaagctgctgcaggaagacaattgcgac
atcttccagaacctcagcaagcgccagcggcagagcctgcgcaagatggtcatcgacatg
gtgctggccacggacatgtccaaacacatgaccctcctggcagacctgaagaccatggtg
gagaccaagaaagtgaccagctcgggggtcctcctgctggacaactactccgaccgcatc
caggtccttcggaacatggtgcactgtgcggacctcagcaaccccaccaaacccctggag
ctgtaccgccagtggaccgaccgcatcatggccgagttcttccagcagggcgaccgggag
cgggagcggggcatggagatcagccccatgtgcgacaagcacacggcctcggtggagaag
tctcaggtgggtttcatcgactatattgtacacccgctgtgggagacgtgggctgacctg
gtccacccagatgcgcaggagatcctggacacgttggaagacaaccgggactggtactac
agtgccatccggcagagcccttcaccaccgcccgaggaggaccccagagggccaggccac
ccacccccaccggataagttccagtttgagctgacgctggaggaagaggaggaggaggac
gtgtctacttccccaggtgcatttgaagcgcggcacttgtccctggctcaggatccatcc
ccagctgaggaactatgggaggtggatggccaggctatggccgcagaggtgaaggtaaag
gaaccgcgcttcacacagcaaggcgactcagcagatagtgtggctgcgggcgaggacgag
tccatgtccccagatgcatccgtggaagctgggggccgcagcagacccctggccctgtct
gctgagagtccccctctgcctgccttgaggaccctgccccctccagaggaagccccgggc
ctcctgggcctcccctccatggcggccgaggtgggggcccaaaaagagcatcaggctgcc
aagagggtgtgcagcgcctgcacaggaacatctggcgaggaccctcccccactcccagct
cctggtgggtgggggtcagctggaggtcctacttga
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