Nicotiana sylvestris (wood tobacco): 104228283
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Entry
104228283 CDS
T05026
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha 1, mitochondrial-like isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
nsy
Nicotiana sylvestris (wood tobacco)
Pathway
nsy00280
Valine, leucine and isoleucine degradation
nsy00640
Propanoate metabolism
nsy00785
Lipoic acid metabolism
nsy01100
Metabolic pathways
nsy01110
Biosynthesis of secondary metabolites
nsy01210
2-Oxocarboxylic acid metabolism
Module
nsy_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nsy00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
104228283
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
104228283
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
104228283
Enzymes [BR:
nsy01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
104228283
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Motif
Pfam:
E1_dh
DXP_synthase_N
Transketolase_N
TPP_enzyme_C
GspH
Motif
Other DBs
NCBI-GeneID:
104228283
NCBI-ProteinID:
XP_009779029
UniProt:
A0A1U7WWH5
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Position
10:complement(35425461..35443222)
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AA seq
459 aa
AA seq
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MATWISRSTRSFSHFLQRAGSLSILHQRGLRPFSYFESTKGREQIECPHKYEKDNYHLEI
NLDENQALDFPGGKIPFTSQMKFIPESSETRLACYRVLDKNGYQIPGSVFEQVSKDLAVK
MYRKMVTLQIMDSIFDEAKKQGRLSFYLTTLGEEVINIASAAALTSDDIVLPQYREPGVL
LWRGFTLQEFANQLLGNKGDNGKGRQMPIHYGSNKLNYFTVSSTIATQLPQAVGVAYSLK
MDTKEACVVTYFGDGTTSEGDFHAALNLAAVLEVPVIFVCRNNGWAISTPVAEQFRSDGI
AIKGQAYGVRSIRVDGNDALAVYSAIRAARKMAIKEQRPILVEAMAYRVGDHASSDDSTK
YRSKEEIEYWRRRSSVARFRKWIQKNGWWSDVEEFEFRGNIREQVLQAIQVAEKEEKPPL
VDLFTDVYDQIPSNLQEQERYIRDAVKRGPKEYPSNMTL
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atggccacttggatttcaagatcaacaagaagcttttcccattttcttcaaagggctggt
tccttatctattctccaccagagaggtttaaggccattttcctatttcgagtccacaaaa
ggaagagagcaaatagagtgcccacacaaatatgagaaggataattatcatcttgaaatt
aatcttgatgagaaccaagccttggatttcccaggaggaaagattccatttacttctcaa
atgaaattcattcctgaatcatccgaaacaaggttagcttgttatcgagttcttgacaaa
aatggctatcaaattccaggcagtgtattcgagcaggtgagcaaagatttagcagtgaaa
atgtatagaaaaatggttacccttcaaattatggacagcattttcgatgaagcaaaaaaa
cagggcaggttatccttttatttaacaactcttggagaagaagtcataaacatagcttct
gctgctgccctcacctcagatgacattgtgttgcctcagtacagggagcccggggttctc
ttatggcgtggcttcaccctacaagaatttgccaatcaattgctaggaaacaagggtgac
aatgggaaaggaaggcaaatgccaatacattatggttctaacaagctcaattacttcacc
gtttcttcaactatagccacacagcttccacaggcagtaggcgtggcttattctctgaaa
atggacacaaaagaggcttgtgttgtcacttattttggagatggtaccactagtgaggga
gatttccatgctgctttgaatcttgcagcagttctggaagttcctgttatatttgtatgc
cgcaataatggatgggcaattagcacccctgtggccgaacaatttcgaagtgatggaatc
gcgattaaagggcaagcttatggagttcgaagcattcgagtggatggcaatgatgctctt
gcagtttatagtgctattcgtgctgctcgtaaaatggcaataaaggaacaaaggccaata
ttagtcgaggccatggcttatcgagtgggcgaccatgcatcgtctgatgattctaccaag
taccgatccaaggaggaaattgagtactggagaagacgaagctcagtcgccagattcaga
aaatggatacagaaaaatggttggtggagtgatgtagaggaattcgaattccggggaaat
atcagagagcaggtgttgcaagcaattcaagttgctgagaaagaagagaaacctccgttg
gtagatttgtttacagatgtttatgaccaaataccatcaaatcttcaagaacaagagagg
tatattagagatgctgtgaagagaggtccaaaagagtatccttctaatatgactctatag
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