Natranaerobius thermophilus: Nther_1125
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Entry
Nther_1125 CDS
T00761
Name
(GenBank) uroporphyrinogen-III C-methyltransferase, uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
nth
Natranaerobius thermophilus
Pathway
nth00860
Porphyrin metabolism
nth01100
Metabolic pathways
nth01110
Biosynthesis of secondary metabolites
nth01120
Microbial metabolism in diverse environments
nth01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
nth00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Nther_1125
Enzymes [BR:
nth01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Nther_1125
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Nther_1125
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Fucose_iso_N1
Motif
Other DBs
NCBI-ProteinID:
ACB84708
UniProt:
B2A1G8
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All DBs
Position
1192196..1193746
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AA seq
516 aa
AA seq
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MSGRVYLIGAGPGDEGLITVKGLNCVKEANVIVYDRLIPQALLRYAPSTAEFIFVGKSPE
KHTLTQEEINDLLIEQAEQGKIIARLKGGDPFVFGRGGEEVIALKEHNIPFEVVPGITSA
VAAPMYAGIPVTHRGLSSSFAVITGHEDPDKAESSISWQDLALESGTLCFLMGVGNLSRI
VDNLLAHGKDSETPIALVRWGTRPYQKTLTGTLSNIVEKAKSENFKSPAVIIIGEVVNLR
EQLAWFEKKPFFNKNILVTRARSQASELSYKISQLGGQPVEFPTIKIEKPDTYQPLDEAI
KKLAEYNWLVFTSVNGVKHFFNRLENLDYDCRQLAGLKTCAIGSKTKESLEEKGIKADVV
PQEYRAEALIDLMKEQVKSGDRVLIPRAKEAREVLPEALREQGLKVDVITAYETVKDTKD
TEKVRKMLKQNELDAITFTSSSTVKNFVEVLELNVGLNEPGAVLANTHIACIGPITASTC
QQYGIEVNSIANEYTIPGLVESLIDNLDENVEEEFK
NT seq
1551 nt
NT seq
+upstream
nt +downstream
nt
gtgtcagggagagtatatttaataggtgcgggcccaggagatgaaggcctaattactgtc
aaaggcctaaactgtgtcaaagaagctaatgtaattgtttatgaccggcttattccccaa
gctttattgcgatatgcaccttctactgccgagtttatatttgtgggcaaaagccctgaa
aaacatactttaacacaagaagaaataaatgatttattaattgaacaagctgagcaaggt
aaaattattgcaagattaaagggcggtgatccctttgtatttggcaggggaggtgaggag
gtcatagctttaaaagaacataatataccttttgaagtggtacctggtataacttcagca
gtagcagctcctatgtatgcaggaataccagttactcaccgaggactaagttcaagtttt
gcggtcataaccggtcatgaggatccggacaaagctgaaagttctatctcatggcaagac
ttagccttagaaagtggaactttgtgtttcttgatgggagtgggtaacctctccagaata
gttgataacttgctggcccatggaaaagattctgaaacccctatagctttagttagatgg
gggactcgcccctatcagaaaaccctgaccggtaccctatcgaatatagtagaaaaagca
aagagcgaaaactttaaatcaccggcggtaatcataattggtgaagtggtaaatttacga
gaacaactggcttggtttgaaaagaagcccttttttaataaaaatattctagttactagg
gcgagaagtcaggctagtgaactttcatataaaatttcccaactgggtggtcaacctgtg
gagttccccacaattaaaatagaaaaacctgatacataccaacccctggatgaagctatt
aaaaaattggctgaatataactggctggtttttactagtgttaacggggtgaaacacttt
tttaatagattagaaaatttagattatgattgtagacaactcgccggcttaaaaacttgt
gctattggttctaaaactaaagaatctttagaagagaagggtataaaggctgatgtagtg
ccccaagaatatagagctgaagcattgatcgacttaatgaaagagcaagttaaatcaggt
gatcgtgtcctaattccccgtgcaaaagaagctagagaagtactgccggaagctttaagg
gagcagggcttaaaagtggatgtaattactgcttatgaaacagtaaaagacactaaagac
acagaaaaagtccggaaaatgttaaaacaaaatgagttagacgccatcacattcactagt
tcttctacggtaaaaaattttgtggaagtgttagaattaaatgtagggttaaatgaacca
ggcgccgtactagctaacactcatattgcatgtatcggccctatcactgctagtacttgc
caacagtatggtatagaagttaattcaattgccaatgaatatacaattccaggtctggta
gaatccttgatagataatctggatgagaacgtggaggaggagtttaaatga
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