Natranaerobius thermophilus: Nther_1300
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Entry
Nther_1300 CDS
T00761
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nth
Natranaerobius thermophilus
Pathway
nth00300
Lysine biosynthesis
nth00550
Peptidoglycan biosynthesis
nth01100
Metabolic pathways
nth01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nth00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Nther_1300
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Nther_1300
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Nther_1300
Enzymes [BR:
nth01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Nther_1300
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
ABC_ATPase
Ysc84
Motif
Other DBs
NCBI-ProteinID:
ACB84883
UniProt:
B2A2G8
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Position
1372400..1373728
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AA seq
442 aa
AA seq
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MGDPDTVITGFSVDSRYVKQGDMFVCLPGDKTDGHNFIDEAIDNGARGCLVNRDIELSRR
HSVHPPLVIKVNDTLMALQEIARKHRQKFGVSVVAVTGSIGKTTTKDMIASVLAEKYSIL
KTHGNLNSEIGLPLMLLELTQHHQVAVLEMGMNNQGEIARLCELARPNVGVITRIAESHI
EKLGSLENIAEAKGELLENLLPGGTAILNCDDNWVRRLRSKVPGEVLYYGLTDGDLSAYN
VRVDKDKTNAKIMSNDKSEQLNLPLIGKHNLSNALAAIAVGRVFGLDLTQSIRALEGFTG
TSMRNQIKYHKDMIIIDDTYNANVQSTLAAFDVLTNLPLNRRIAVLGDMFELGDYTEKAH
KTVGEQAVNRGFDYLITVGELSKTTQEAADKLGMPEHQNIHVADREQAIQRILQIVKSGD
GILVKGSRGMAMEKIVNSLLKT
NT seq
1329 nt
NT seq
+upstream
nt +downstream
nt
atgggtgaccctgatactgtcattactggctttagtgtggattcacgttatgtcaagcag
ggcgatatgtttgtatgcttaccgggagataaaaccgatggtcataattttatagacgaa
gcaattgataatggtgcccgaggatgtctagtaaatcgtgatattgaactgtctcgacgt
cattcagtccatccacccttggtaataaaagtcaatgatacgttgatggccctgcaagaa
atagccagaaagcatcgacaaaaatttggcgtttctgtggtagctgttactggtagtatt
ggtaaaactaccaccaaagatatgatcgccagtgttttagctgaaaagtactctatttta
aaaacccacggtaatttgaatagtgaaattggactccctttgatgttattggaattaact
caacatcatcaagttgctgtacttgaaatgggaatgaacaatcaaggagaaatagccagg
ttatgtgagttggcaagacctaatgtaggtgttatcacaaggattgccgagtctcatata
gagaagctgggcagtttagaaaacattgcagaagctaaaggtgaactgttggagaattta
ttgcctggtgggactgctattttgaattgcgatgataactgggttagacgactgaggtct
aaagttccaggtgaagttttatactatggtttaacagatggagatttatcggcttataat
gtcagagtcgacaaggacaaaacgaatgcgaaaattatgagtaatgataaaagtgagcag
ctaaacttacctttaattggaaagcataacttgagtaatgctttggcggcaattgctgtt
ggtagagtctttggactcgatttgactcaatctatccgtgcacttgaaggttttactggt
acatcaatgaggaatcaaataaagtatcataaagacatgataattattgatgatacttat
aatgccaatgtacaatctaccttggcagcctttgatgtattaacaaatttaccactcaac
cgtagaatagccgttttaggagatatgttcgaattaggtgattatacagaaaaagctcac
aaaactgtgggtgaacaggctgtaaacaggggatttgattatttgattacagttggtgaa
ctatcaaaaaccactcaagaagcagctgataagttgggaatgcctgagcatcaaaacatt
catgttgctgatcgtgaacaggctattcaaaggatattacagatagttaaatctggagat
ggaatacttgttaagggttctagaggtatggctatggaaaagatagtaaattcgttgtta
aaaacttag
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