Nocardia terpenica: CRH09_12655
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Entry
CRH09_12655 CDS
T05168
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ntp
Nocardia terpenica
Pathway
ntp00300
Lysine biosynthesis
ntp00550
Peptidoglycan biosynthesis
ntp01100
Metabolic pathways
ntp01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ntp00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CRH09_12655
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CRH09_12655
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CRH09_12655
Enzymes [BR:
ntp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CRH09_12655
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ATL66928
UniProt:
A0A291RHZ8
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All DBs
Position
2864811..2866418
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AA seq
535 aa
AA seq
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MIEMTLREIAAVVGGTLHDVPDPAVTVTGAVEFDSRRINPGDLFLALPGEHVDGHDYAPA
AIAAGAVAVLSARPVGVPAIVVAPGEKHAGGKGDAPAGGSGDALAGASGDARAEGSGDAP
ARASGEARAVGTAYALAHDKDGSGAAVLGALAKLARAVVDRLVVEHGLTVVGVTGSSGKT
STKDLLAGVLAPLGAVVAPPGSFNNEVGHPWTALRANAETRFLVLELSARGPGHIRALTE
IAPPSIGVVLNVGTAHLGEFGGRDAIARAKGELVEALPPTGLAVLNADDDRVAAMAERTR
ARVVTVGLSEGADLRATDIRLDETARARFTLHANGSRVDVRLAVHGEHQVGNALSAAAVA
LECGADLETVAAALSDARVASAHRMDVRTRADGVTVVNDSYNANPDSVRAALKALVTMSR
AGDEPRRSWAVLGEMAELGAESVLEHDRIGRLAVRLDVDRLIVVGTGRPARAMHQGAVME
GSWGEESLLVPDLESAIAVLDAELGAGDVVLVKASNSIGLWAVAQHLTQAREAAR
NT seq
1608 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagatgaccctgcgggagatcgcggccgtcgtcggcggaacgctgcacgacgtg
cccgaccccgcggtgaccgtgaccggtgcggtcgaattcgattcgcgccgaatcaatccc
ggcgacctgttcctggccctccccggcgaacacgtcgacggccacgactacgcccccgcc
gccatagccgccggagccgtagcagtcctatccgcccgccccgtaggcgtccccgcaatc
gtggtggcccccggcgaaaagcacgccgggggaaagggagacgcgcctgccggggggagt
ggtgatgcgcttgccggggcgagtggagacgcgcgtgccgaggggagtggagacgcgcct
gcccgggcaagtggtgaggctcgggctgtcggtacggcctatgcgctggcgcacgacaag
gatgggtcgggggccgctgtgttgggggcgctggcgaaattggctcgggccgtggtggat
cggctggtggtcgagcatgggctgaccgttgtcggggttaccgggtcgtcggggaagact
tctacgaaggatctgctggctggggtgttggctccgctgggggcggtggttgcgccgccg
gggtcgttcaacaatgaggtcgggcatccgtggacggcgttgcgggcgaatgccgagacg
cggtttctggtgttggagctgtcggcgcgggggccggggcatattcgggcgcttaccgag
atcgcgccgccgagtatcggggtggtgttgaatgtgggcaccgcgcatctcggggagttc
ggtggtcgggatgccattgcgcgggccaaaggtgaactggtggaggcgcttccgccgacg
gggctggccgtgctcaatgccgacgacgatcgggtggccgccatggcggagaggacccgc
gcccgcgtggtgaccgtcggcctgtcggagggagcggacctgcgcgccaccgacattcgg
ctcgacgagaccgcgcgcgcccgattcaccctgcacgccaacggttcccgggtcgacgtg
cggctcgcggtgcacggcgagcaccaggtcggcaacgccctgtccgccgccgcggtcgcg
ctggagtgcggcgcggatctcgagaccgtggccgccgccctgtccgacgcccgggtggcg
tcggcgcaccgcatggacgtgcgcacccgcgccgacggcgtcaccgtcgtcaacgactcc
tacaacgccaatcccgactcggtgcgggcggcgctcaaggcgttggtgacgatgtcgcga
gccggcgacgagccccgccgcagctgggcggtgctcggcgaaatggccgagctgggtgcg
gaatcggtgctcgaacacgatcggatcggccgcctcgcggtccggctggacgtcgatcgg
ctgatcgtcgtcggcaccggccgcccggcccgcgcgatgcaccagggcgcggtgatggaa
ggctcgtggggcgaggagtccctgctggtgcccgatctggagtccgcgatcgcggtgctg
gacgcggaactcggcgcgggtgacgtggtgctggtcaaggcgtcgaactcgatcggcctg
tgggcggtcgcccagcacctgacgcaagcccgggaggcggcgagatga
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