KEGG   Neogale vison (American mink): 122889452
Entry
122889452         CDS       T08764                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
nvs  Neogale vison (American mink)
Pathway
nvs01522  Endocrine resistance
nvs04010  MAPK signaling pathway
nvs04012  ErbB signaling pathway
nvs04014  Ras signaling pathway
nvs04024  cAMP signaling pathway
nvs04068  FoxO signaling pathway
nvs04071  Sphingolipid signaling pathway
nvs04137  Mitophagy - animal
nvs04140  Autophagy - animal
nvs04141  Protein processing in endoplasmic reticulum
nvs04210  Apoptosis
nvs04215  Apoptosis - multiple species
nvs04217  Necroptosis
nvs04310  Wnt signaling pathway
nvs04380  Osteoclast differentiation
nvs04510  Focal adhesion
nvs04530  Tight junction
nvs04620  Toll-like receptor signaling pathway
nvs04621  NOD-like receptor signaling pathway
nvs04622  RIG-I-like receptor signaling pathway
nvs04625  C-type lectin receptor signaling pathway
nvs04657  IL-17 signaling pathway
nvs04658  Th1 and Th2 cell differentiation
nvs04659  Th17 cell differentiation
nvs04660  T cell receptor signaling pathway
nvs04664  Fc epsilon RI signaling pathway
nvs04668  TNF signaling pathway
nvs04722  Neurotrophin signaling pathway
nvs04723  Retrograde endocannabinoid signaling
nvs04728  Dopaminergic synapse
nvs04750  Inflammatory mediator regulation of TRP channels
nvs04910  Insulin signaling pathway
nvs04912  GnRH signaling pathway
nvs04914  Progesterone-mediated oocyte maturation
nvs04917  Prolactin signaling pathway
nvs04920  Adipocytokine signaling pathway
nvs04926  Relaxin signaling pathway
nvs04930  Type II diabetes mellitus
nvs04931  Insulin resistance
nvs04932  Non-alcoholic fatty liver disease
nvs04933  AGE-RAGE signaling pathway in diabetic complications
nvs04935  Growth hormone synthesis, secretion and action
nvs04936  Alcoholic liver disease
nvs05010  Alzheimer disease
nvs05012  Parkinson disease
nvs05016  Huntington disease
nvs05017  Spinocerebellar ataxia
nvs05020  Prion disease
nvs05022  Pathways of neurodegeneration - multiple diseases
nvs05132  Salmonella infection
nvs05133  Pertussis
nvs05135  Yersinia infection
nvs05142  Chagas disease
nvs05145  Toxoplasmosis
nvs05152  Tuberculosis
nvs05161  Hepatitis B
nvs05162  Measles
nvs05166  Human T-cell leukemia virus 1 infection
nvs05167  Kaposi sarcoma-associated herpesvirus infection
nvs05169  Epstein-Barr virus infection
nvs05170  Human immunodeficiency virus 1 infection
nvs05171  Coronavirus disease - COVID-19
nvs05200  Pathways in cancer
nvs05208  Chemical carcinogenesis - reactive oxygen species
nvs05210  Colorectal cancer
nvs05212  Pancreatic cancer
nvs05231  Choline metabolism in cancer
nvs05415  Diabetic cardiomyopathy
nvs05417  Lipid and atherosclerosis
nvs05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nvs00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    122889452 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122889452 (MAPK10)
   04012 ErbB signaling pathway
    122889452 (MAPK10)
   04014 Ras signaling pathway
    122889452 (MAPK10)
   04310 Wnt signaling pathway
    122889452 (MAPK10)
   04668 TNF signaling pathway
    122889452 (MAPK10)
   04068 FoxO signaling pathway
    122889452 (MAPK10)
   04071 Sphingolipid signaling pathway
    122889452 (MAPK10)
   04024 cAMP signaling pathway
    122889452 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    122889452 (MAPK10)
   04137 Mitophagy - animal
    122889452 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    122889452 (MAPK10)
   04215 Apoptosis - multiple species
    122889452 (MAPK10)
   04217 Necroptosis
    122889452 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122889452 (MAPK10)
   04530 Tight junction
    122889452 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    122889452 (MAPK10)
   04621 NOD-like receptor signaling pathway
    122889452 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    122889452 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    122889452 (MAPK10)
   04660 T cell receptor signaling pathway
    122889452 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    122889452 (MAPK10)
   04659 Th17 cell differentiation
    122889452 (MAPK10)
   04657 IL-17 signaling pathway
    122889452 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    122889452 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    122889452 (MAPK10)
   04920 Adipocytokine signaling pathway
    122889452 (MAPK10)
   04912 GnRH signaling pathway
    122889452 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    122889452 (MAPK10)
   04917 Prolactin signaling pathway
    122889452 (MAPK10)
   04926 Relaxin signaling pathway
    122889452 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    122889452 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    122889452 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    122889452 (MAPK10)
   04722 Neurotrophin signaling pathway
    122889452 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    122889452 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    122889452 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122889452 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    122889452 (MAPK10)
   05231 Choline metabolism in cancer
    122889452 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    122889452 (MAPK10)
   05212 Pancreatic cancer
    122889452 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    122889452 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    122889452 (MAPK10)
   05161 Hepatitis B
    122889452 (MAPK10)
   05171 Coronavirus disease - COVID-19
    122889452 (MAPK10)
   05162 Measles
    122889452 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122889452 (MAPK10)
   05169 Epstein-Barr virus infection
    122889452 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    122889452 (MAPK10)
   05135 Yersinia infection
    122889452 (MAPK10)
   05133 Pertussis
    122889452 (MAPK10)
   05152 Tuberculosis
    122889452 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    122889452 (MAPK10)
   05142 Chagas disease
    122889452 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    122889452 (MAPK10)
   05012 Parkinson disease
    122889452 (MAPK10)
   05016 Huntington disease
    122889452 (MAPK10)
   05017 Spinocerebellar ataxia
    122889452 (MAPK10)
   05020 Prion disease
    122889452 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    122889452 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122889452 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    122889452 (MAPK10)
   05415 Diabetic cardiomyopathy
    122889452 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    122889452 (MAPK10)
   04936 Alcoholic liver disease
    122889452 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    122889452 (MAPK10)
   04931 Insulin resistance
    122889452 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    122889452 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    122889452 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nvs01001]
    122889452 (MAPK10)
Enzymes [BR:nvs01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     122889452 (MAPK10)
Protein kinases [BR:nvs01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   122889452 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 122889452
NCBI-ProteinID: XP_044080531
LinkDB
Position
11:120840632..121186922
AA seq 464 aa
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttattgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgataaccagttctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaatttgaagcctattggctctggggctcagggaatagtttgtgct
gcgtatgatgctgttcttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacgcatgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aagaacattattagtttattaaatgtcttcacaccccagaaaacattggaggagttccaa
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctataccaaatgttgtgtggcatcaagcacctt
cattctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaagtctgat
tgtacattgaaaatccttgactttggactggccaggacggcaggcacgagcttcatgatg
actccttatgtggtcacacgttattatagagcccccgaggttattctgggaatgggctac
aaggagaatgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaggtaattgagcaactagga
acaccatgtccggaattcatgaagaaattgcaacctacagtaagaaactatgtggagaat
cggcccaagtatgcaggactcaccttccccaagctctttccagattccctcttcccagcg
gactctgagcacaataaactcaaagccagccaagccagggacttactgtcgaagatgcta
gtgatcgacccagcaaaaagaatatcggtggatgacgccttacagcatccttacatcaat
gtttggtatgaccctgccgaagtggaggcgcctccacctcagatttatgacaaacaattg
gatgaaagagagcacaccattgaagaatggaaagaacttatctacaaagaagtaatgaat
tcagaagaaaagactaaaaacggtgttgtaaaaggacaaccgtctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcttcgtccgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcttcagcaggacccctg
ggttgttgcaggtga

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