Neogale vison (American mink): 122892410 Help Entry 122892410         CDS       T08764                                  Symbol ADCY6 Name (RefSeq) adenylate cyclase type 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism nvs  Neogale vison (American mink) Pathway nvs00230   Purine metabolism nvs01100   Metabolic pathways nvs01522   Endocrine resistance nvs04015   Rap1 signaling pathway nvs04022   cGMP-PKG signaling pathway nvs04024   cAMP signaling pathway nvs04062   Chemokine signaling pathway nvs04072   Phospholipase D signaling pathway nvs04081   Hormone signaling nvs04082   Neuroactive ligand signaling nvs04114   Oocyte meiosis nvs04211   Longevity regulating pathway nvs04213   Longevity regulating pathway - multiple species nvs04261   Adrenergic signaling in cardiomyocytes nvs04270   Vascular smooth muscle contraction nvs04371   Apelin signaling pathway nvs04540   Gap junction nvs04611   Platelet activation nvs04713   Circadian entrainment nvs04714   Thermogenesis nvs04723   Retrograde endocannabinoid signaling nvs04724   Glutamatergic synapse nvs04725   Cholinergic synapse nvs04727   GABAergic synapse nvs04742   Taste transduction nvs04750   Inflammatory mediator regulation of TRP channels nvs04911   Insulin secretion nvs04912   GnRH signaling pathway nvs04913   Ovarian steroidogenesis nvs04914   Progesterone-mediated oocyte maturation nvs04915   Estrogen signaling pathway nvs04916   Melanogenesis nvs04918   Thyroid hormone synthesis nvs04921   Oxytocin signaling pathway nvs04923   Regulation of lipolysis in adipocytes nvs04924   Renin secretion nvs04925   Aldosterone synthesis and secretion nvs04926   Relaxin signaling pathway nvs04927   Cortisol synthesis and secretion nvs04928   Parathyroid hormone synthesis, secretion and action nvs04934   Cushing syndrome nvs04935   Growth hormone synthesis, secretion and action nvs04961   Endocrine and other factor-regulated calcium reabsorption nvs04962   Vasopressin-regulated water reabsorption nvs04970   Salivary secretion nvs04971   Gastric acid secretion nvs04972   Pancreatic secretion nvs04976   Bile secretion nvs05032   Morphine addiction nvs05163   Human cytomegalovirus infection nvs05166   Human T-cell leukemia virus 1 infection nvs05200   Pathways in cancer nvs05207   Chemical carcinogenesis - receptor activation nvs05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:nvs00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     122892410 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     122892410 (ADCY6)    04371 Apelin signaling pathway     122892410 (ADCY6)    04072 Phospholipase D signaling pathway     122892410 (ADCY6)    04024 cAMP signaling pathway     122892410 (ADCY6)    04022 cGMP-PKG signaling pathway     122892410 (ADCY6)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     122892410 (ADCY6)    04081 Hormone signaling     122892410 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     122892410 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     122892410 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     122892410 (ADCY6)    04062 Chemokine signaling pathway     122892410 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     122892410 (ADCY6)    04923 Regulation of lipolysis in adipocytes     122892410 (ADCY6)    04912 GnRH signaling pathway     122892410 (ADCY6)    04913 Ovarian steroidogenesis     122892410 (ADCY6)    04915 Estrogen signaling pathway     122892410 (ADCY6)    04914 Progesterone-mediated oocyte maturation     122892410 (ADCY6)    04921 Oxytocin signaling pathway     122892410 (ADCY6)    04926 Relaxin signaling pathway     122892410 (ADCY6)    04935 Growth hormone synthesis, secretion and action     122892410 (ADCY6)    04918 Thyroid hormone synthesis     122892410 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     122892410 (ADCY6)    04916 Melanogenesis     122892410 (ADCY6)    04924 Renin secretion     122892410 (ADCY6)    04925 Aldosterone synthesis and secretion     122892410 (ADCY6)    04927 Cortisol synthesis and secretion     122892410 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     122892410 (ADCY6)    04270 Vascular smooth muscle contraction     122892410 (ADCY6)   09154 Digestive system    04970 Salivary secretion     122892410 (ADCY6)    04971 Gastric acid secretion     122892410 (ADCY6)    04972 Pancreatic secretion     122892410 (ADCY6)    04976 Bile secretion     122892410 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     122892410 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     122892410 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     122892410 (ADCY6)    04727 GABAergic synapse     122892410 (ADCY6)    04725 Cholinergic synapse     122892410 (ADCY6)    04723 Retrograde endocannabinoid signaling     122892410 (ADCY6)   09157 Sensory system    04742 Taste transduction     122892410 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     122892410 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     122892410 (ADCY6)    04213 Longevity regulating pathway - multiple species     122892410 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     122892410 (ADCY6)    04714 Thermogenesis     122892410 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122892410 (ADCY6)    05207 Chemical carcinogenesis - receptor activation     122892410 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     122892410 (ADCY6)    05163 Human cytomegalovirus infection     122892410 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     122892410 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     122892410 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     122892410 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     122892410 (ADCY6) Enzymes [BR:nvs01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      122892410 (ADCY6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  122892410 NCBI-ProteinID:  XP_044084815 LinkDB All DBs Position 12:complement(85175642..85196176) Genome browser AA seq 1166 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRPRRGTRTGGFCTPRYMSCLREAQPPSPSPAAPP RCPWQDEAFIRRGGPGKGTELGLRAVALGFEDTEATAAVGAADAVPDGSPRRRWSCWRRL AQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPAPPQPAYVA LLACAATLFVALMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSVGLWCP VFFVYITYTLLPIRMRAAVFSGLGLSTLHLILAWQLNRGDAFLWKQLGANMLLFLCTNVI GICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKK EDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLR IKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHC GVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYL KEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLVPRWAPDRAFSRTKDSKAFRQM GIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYS RKVDPRFGAYVACALLVFCFICFIQLLVFPHSTVMLGIYAGIFLLLLITVLTCAVSSCGS LFPKALRRLSRSIVRSRAHSTVVGIFSVLLVFTSAIANMFTCNHTPIRNCAARMLNVTPA DITTCHLQQLNYSLGLDTPLCEGTAPTCSFPEYFIGNMLLSLLASSVFLHISSIGKLAMV FVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGPDCPAAGRVALKYMTPVIL LVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLA RERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEE RFRQLEKIKTIGSTYMAASGLNASTYDQAGRSHITALADYAMRLMEQMKHINEHSFNNFQ MKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQ LECRGVVKVKGKGEMTTYFLNGGPPS NT seq 3501 nt NT seq  +upstreamnt  +downstreamnt atgtcgtggtttagtggcctcctggtccccaaagtggatgaacggaaaacagcctggggt gagcgcaatgggcagaagcgtccgcgccgtgggacccggacagggggcttctgcacgccc cgctacatgagctgcctccgggaggcccagccccccagtcccagccctgctgctcccccg cggtgcccctggcaggacgaggccttcatccggaggggtggcccgggcaagggcactgag ctggggctgcgggcggtggccctgggctttgaggacacagaggcgacggcagcagtgggg gcagctgatgcggtgcccgacgggagccccaggcgtcggtggtcgtgctggcggcgtctg gcccaggtgttccagtcgaagcagttccgctcggccaagctggagcgcctgtaccagcgg tacttcttccagatgaaccagagcagcctgacactgctgatggccgtgctggtgctgctc acagccgtgctgctggccttccacgcggcgcctgcccccccgcagcctgcctatgtggcc ctgctggcctgcgccgccaccctcttcgtggcgctcatggtggtgtgcaaccggcacagc ttccgccaggactccatgtgggtggtgagctacgtggtgctgggcatcctggcagctgtg caggtggggggcgccctggcggctgacccccgcagcccctctgtgggcctctggtgcccc gtgtttttcgtctacatcacctacacgctcctgcccatccgcatgcgggcggctgtcttc agtggcctgggcctctccaccctgcatctgatcttggcttggcaactcaaccgcggggac gccttcctctggaagcagctgggcgccaacatgctgctgttcctctgcaccaatgtcatt ggcatctgcacacactacccggcggaggtgtctcagcgccaggcctttcaggagacccga ggttatatccaggcccggctgcacctgcagcacgagaaccggcagcaggaacggctgctg ctgtccgtgttgccccagcatgttgccatggagatgaaagaagatatcaacacaaagaaa gaagacatgatgttccacaagatctacatccagaagcatgacaatgtcagcatcctgttt gcggacattgaaggcttcaccagcctggcgtcccagtgcaccgcacaggagctggtcatg accctgaacgagctctttgcccggtttgacaagctggctgcggaaaatcactgcctgagg atcaagatcttaggggactgttactactgtgtgtcggggctgccggaggcccgggcagac catgcccactgctgtgtggagatgggggtggacatgatcgaggccatctcgctggtgcgc gaggtgacaggtgtgaacgtgaacatgcgcgtgggcatccacagcgggcgtgtgcactgt ggtgtcctcggcctgcggaaatggcagttcgacgtgtggtccaacgacgtgacgctggcc aaccacatggaggcggggggccgggccggccgtatccacatcacccgggccacgctgcag tacctgaatggggactacgaggtggagccaggccgtggtggtgagcggaacgcatacctc aaagagcagcacatcgagaccttcctcatcctgggagccagccagaaacggaaagaggag aaggccatgctggccaagctgcagcggacgcgggccaactccatggaagggctggtgcca cgctgggcgcctgaccgcgccttctcccggaccaaggactccaaggctttccgtcagatg ggcattgatgattccagcaaggacaaccggggtgcccaagatgccctgaaccccgaggat gaagtagatgagttcctgggccgcgccatcgatgcccgcagcatcgaccagctacggaag gaccatgtgcgccgcttcctgctcactttccagagagaggatcttgaaaagaagtactcg cggaaggtggacccccgcttcggagcctacgtggcctgtgcgctgttggtcttctgcttc atctgctttatccagctcctcgtcttcccacactccaccgtgatgcttggcatctatgcc ggtatcttcctgctgttgctgatcactgtgctgacctgtgccgtgtcctcctgtggctct ctcttccccaaggccctgcgccgtctttcccgcagcattgtccgctctcgggcacacagc actgtggttggcatcttttcagtcttgcttgtgttcacctctgccatcgccaacatgttc acctgcaaccacacccccatacgaaactgtgcagcccggatgctgaatgtgacacctgct gacatcaccacctgtcacctgcagcagctcaattactctctgggcctggacactcccctg tgtgagggcaccgcacccacttgcagcttccctgagtacttcattgggaacatgctgctg agtctcttggccagctctgtcttcctgcacatcagcagcattggaaagctggccatggtc tttgtcctggggctcatctatttggtgctgcttctgctgggccccccagccaccatcttt gacaactacgacttgctgcttggtgtccatggcttggcttcttccaatgagactttcgat gggccggactgcccagctgccgggagggtggcgctcaagtacatgacccccgtgattctg ctggtgtttgcgctggctctgtatctgcatgcccagcaggtggaatcgactgcccggctg gacttcctctggaaactgcaggcaacaggggagaaggaggagatggaggaactgcaggca tacaaccggaggctgctgcataacattctgcccaaggacgtggctgcccacttcctggcc cgggagcgtcggaacgatgagctctactaccagtcgtgtgaatgtgtggccgtcatgttt gcctccattgccaacttttctgagttctatgtggaactggaggcaaacaatgagggtgtc gagtgcctgcggctgctcaatgagatcattgctgactttgatgagatcatcagcgaggag cgcttccggcagctggagaagatcaagacgattgggagcacctacatggcagcctcagga ctgaacgccagcacctacgatcaggccggccgctcccacatcactgccctggcagactat gccatgcggctcatggagcagatgaaacacatcaacgagcactccttcaacaatttccag atgaagattgggctgaacatgggcccagttgtggcaggcgtcattggggctcggaagccg cagtatgacatctgggggaacacagtgaatgtctctagccgtatggacagcacgggtgtc cctgaccgaatccaggtgaccacggacttgtaccaggttctagctgccaaaggctaccag ctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctacttcctc aatgggggcccccccagttag

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