Neogale vison (American mink): 122893168
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Entry
122893168 CDS
T08764
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs00020
Citrate cycle (TCA cycle)
nvs00480
Glutathione metabolism
nvs01100
Metabolic pathways
nvs01200
Carbon metabolism
nvs01210
2-Oxocarboxylic acid metabolism
nvs01230
Biosynthesis of amino acids
nvs04146
Peroxisome
nvs05230
Central carbon metabolism in cancer
Module
nvs_M00009
Citrate cycle (TCA cycle, Krebs cycle)
nvs_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
122893168 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
122893168 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
122893168 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
122893168 (IDH2)
Enzymes [BR:
nvs01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
122893168 (IDH2)
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
122893168
NCBI-ProteinID:
XP_044085950
UniProt:
A0A8C7ETD3
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Position
13:complement(147089382..147107577)
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AA seq
451 aa
AA seq
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MAGYLRVVRSLCRASGSGPAWASAAPTGPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPHRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVVDRAGTFKIVFSPKDGSGTKEWEVYNFPGGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKNNLDKALGH
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atggctggctacctgcgggtcgtacgctcgctctgcagagcctccggctccgggccggcc
tgggcgtcggcagccccgacgggccccaacttgcaggagcagccgcggcgccactatgcc
gacaagaggatcaaggtggcgaagccggtggtggagatggacggcgacgagatgacccgg
atcatctggcagttcatcaaggagaagctcatcctaccccatgtggacgtccagctcaag
tatttcgatctggggctcccgcaccgtgaccagaccaacgaccaggtcaccatagactcg
gcgttggccacccagaagtacagtgtggccgtcaagtgtgccaccatcacccccgatgag
gcccgtgtggaagagttcaagctgaagaagatgtggaagagtcccaacgggaccattcgg
aacatcctcggggggaccgtcttccgggaacccatcatttgcaaaaacatcccccgcctg
gtcccgggctggaccaagcccatcaccatcggcaggcacgcccacggcgaccagtacaag
gccacggactttgtggtggaccgggccggcacgtttaagatcgtcttctccccgaaggac
ggcagtggcacgaaggagtgggaggtgtacaacttccccggcggcggcgtggggatgggc
atgtacaataccgacgagtccatctcgggtttcgcacacagctgcttccagtacgccatc
cagaagaagtggccgctctacatgagcaccaagaacaccatcctgaaagcctacgacggg
cgcttcaaggacatcttccaggagatctttgagaagcactacaagactgacttcgacaag
aataagatctggtatgagcaccggctcattgatgacatggtggctcaggtcctcaagtct
tcgggcggcttcgtgtgggcctgcaagaactatgacggagatgtgcagtcggacatcctg
gcgcagggctttggctccctcggcctgatgacgtctgtgctggtctgcccagacgggaag
accatcgaggccgaggctgctcatggaacggtcacccgccactaccgggagcaccagaaa
ggccggcctaccagcacgaaccccattgccagcatctttgcctggactcgtggcctggag
caccgggggaagctggacgggaaccaggacctcatcaggtttgcacagaccctggagaaa
gtgtgtgtccagacggtggagagcggagccatgaccaaggacctggcgggctgcatccac
ggcctcagcaatgtgaagctgaatgagcacttcctgaacacctccgacttcctggacacc
atcaagaacaacctggacaaggctctgggccactag
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