Neogale vison (American mink): 122894274
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Entry
122894274 CDS
T08764
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
nvs
Neogale vison (American mink)
Pathway
nvs01521
EGFR tyrosine kinase inhibitor resistance
nvs01522
Endocrine resistance
nvs04010
MAPK signaling pathway
nvs04012
ErbB signaling pathway
nvs04014
Ras signaling pathway
nvs04062
Chemokine signaling pathway
nvs04068
FoxO signaling pathway
nvs04072
Phospholipase D signaling pathway
nvs04150
mTOR signaling pathway
nvs04151
PI3K-Akt signaling pathway
nvs04510
Focal adhesion
nvs04540
Gap junction
nvs04630
JAK-STAT signaling pathway
nvs04650
Natural killer cell mediated cytotoxicity
nvs04660
T cell receptor signaling pathway
nvs04662
B cell receptor signaling pathway
nvs04664
Fc epsilon RI signaling pathway
nvs04714
Thermogenesis
nvs04722
Neurotrophin signaling pathway
nvs04810
Regulation of actin cytoskeleton
nvs04910
Insulin signaling pathway
nvs04912
GnRH signaling pathway
nvs04915
Estrogen signaling pathway
nvs04917
Prolactin signaling pathway
nvs04926
Relaxin signaling pathway
nvs04935
Growth hormone synthesis, secretion and action
nvs05034
Alcoholism
nvs05160
Hepatitis C
nvs05161
Hepatitis B
nvs05163
Human cytomegalovirus infection
nvs05165
Human papillomavirus infection
nvs05200
Pathways in cancer
nvs05205
Proteoglycans in cancer
nvs05206
MicroRNAs in cancer
nvs05207
Chemical carcinogenesis - receptor activation
nvs05208
Chemical carcinogenesis - reactive oxygen species
nvs05210
Colorectal cancer
nvs05211
Renal cell carcinoma
nvs05213
Endometrial cancer
nvs05214
Glioma
nvs05215
Prostate cancer
nvs05220
Chronic myeloid leukemia
nvs05221
Acute myeloid leukemia
nvs05223
Non-small cell lung cancer
nvs05224
Breast cancer
nvs05225
Hepatocellular carcinoma
nvs05226
Gastric cancer
nvs05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122894274 (SOS2)
04012 ErbB signaling pathway
122894274 (SOS2)
04014 Ras signaling pathway
122894274 (SOS2)
04630 JAK-STAT signaling pathway
122894274 (SOS2)
04068 FoxO signaling pathway
122894274 (SOS2)
04072 Phospholipase D signaling pathway
122894274 (SOS2)
04151 PI3K-Akt signaling pathway
122894274 (SOS2)
04150 mTOR signaling pathway
122894274 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
122894274 (SOS2)
04540 Gap junction
122894274 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
122894274 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
122894274 (SOS2)
04660 T cell receptor signaling pathway
122894274 (SOS2)
04662 B cell receptor signaling pathway
122894274 (SOS2)
04664 Fc epsilon RI signaling pathway
122894274 (SOS2)
04062 Chemokine signaling pathway
122894274 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
122894274 (SOS2)
04912 GnRH signaling pathway
122894274 (SOS2)
04915 Estrogen signaling pathway
122894274 (SOS2)
04917 Prolactin signaling pathway
122894274 (SOS2)
04926 Relaxin signaling pathway
122894274 (SOS2)
04935 Growth hormone synthesis, secretion and action
122894274 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
122894274 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
122894274 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122894274 (SOS2)
05206 MicroRNAs in cancer
122894274 (SOS2)
05205 Proteoglycans in cancer
122894274 (SOS2)
05207 Chemical carcinogenesis - receptor activation
122894274 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
122894274 (SOS2)
05231 Choline metabolism in cancer
122894274 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
122894274 (SOS2)
05225 Hepatocellular carcinoma
122894274 (SOS2)
05226 Gastric cancer
122894274 (SOS2)
05214 Glioma
122894274 (SOS2)
05221 Acute myeloid leukemia
122894274 (SOS2)
05220 Chronic myeloid leukemia
122894274 (SOS2)
05211 Renal cell carcinoma
122894274 (SOS2)
05215 Prostate cancer
122894274 (SOS2)
05213 Endometrial cancer
122894274 (SOS2)
05224 Breast cancer
122894274 (SOS2)
05223 Non-small cell lung cancer
122894274 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
122894274 (SOS2)
05160 Hepatitis C
122894274 (SOS2)
05163 Human cytomegalovirus infection
122894274 (SOS2)
05165 Human papillomavirus infection
122894274 (SOS2)
09165 Substance dependence
05034 Alcoholism
122894274 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
122894274 (SOS2)
01522 Endocrine resistance
122894274 (SOS2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
IQ_SEC7_PH
PH_19
DUF5055
RHG20_PH
PH_10
Motif
Other DBs
NCBI-GeneID:
122894274
NCBI-ProteinID:
XP_044087809
LinkDB
All DBs
Position
13:48797113..48880315
Genome browser
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLSYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYQVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPTSSGELNYYDLIRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
DKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEDQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQICDKDDTCEYKNAFELVSKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPDVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
IEKGEQPVSADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
DAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGNASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKMSFSRIAETDLESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNTKSDDDPPAIPPRQPPPPKVKPRVPAPTGTFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTCPNSPN
TPPSTPSPRVPRRCYVLSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPSY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgctggtctcggccctgcggaaggttcaagagcaagtacaccccactctctcagct
aatgaagaatctctctcttatattgaagagctgatttttcagctgcttaataaattatgc
atggctcaaccaaggactgttcaagatgtggaggaacgtgttcaaaagacctttcctcat
ccaattgataagtgggctattgctgatgcacaatctgccatagaaaaacgaaaacgaaga
aatcctctcctactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac
aaagtggactatcaggtatccctgtatattgtggctgtattagagtatatctcagctgat
attttgaagctggctggtaattatgtttttaatatccgacattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgat
ataggtttggtttctctctgtgaagatgaacctacttcttcaggtgaattaaactactat
gaccttatcagaactgaaattgcagaagaaaggcagtatctacgggaactaaatatgatc
ataaaagtgtttcgagaagcctttctttctgacagaaagctgtttaaaccttctgatatt
gacaagattttcagtaacatttcagatatacatgaattaactgtgaaacttttaggtttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatccgttagctggaagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt
ctttctccaaaatttaatgaacatttcagtaagctgatggccagacctgcagtggctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctggtgcctgtttatcattgttggcactattttgaattattaaagcaattgaaagca
tgtagtgaagatcaggaagacagagaatgtttgaaccaagctattactgctcttatgaat
ctccaaggtagtatggaccgaatttacaagcagtattcacctagacgccgacctggggat
cctgtttgccctttttataatcgtcagttaagaagcaagcatctggctattaaaaaaatg
aatgaaattcagaaaaacatagacggatgggaaggcaaagatattggacaatgttgtaat
gaattcattatggaaggtcccttgacacgaattggtgctaaacatgaacgacatattttt
ctctttgatggcttaatgatcagctgtaagcccaatcatagtcagtcacgccttccaggt
tacagtagtgcagagtacagattaaaagaaaaatttgtcatgaggaaaatacaaatatgt
gataaagatgatacttgtgagtacaaaaatgcttttgagttggtgtccaaagatgaaaac
agcataatatttgctgctaagtctgctgaagagaaaaataattggatggccgcacttatt
tctcttcactatcgtagtacactagatcgaatgctagattcagtgttattgaaagaagaa
aatgagcagccactgagattaccaagtcctgacgtgtatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacctgcaaagtagaagtggaatccccattattaaa
ggaggaactgtagtgaaattaattgaaaggttaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacataccgttcattttgtaaaccacaggaattgctaagc
ttactgatagaacgatttgaaattccagagccagaacccactgaagcagataaattggcc
atagagaaaggcgaacagcccgtcagtgcagaccttaaaaggtttcgcaaggaatatgtc
caaccagtacaacttaggatcttaaatgtgtttcggcactgggttgaacaccatttttat
gactttgaaagagatttggaattgcttgaaagactggaatccttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtcaattgctaagatcatcaagagaaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaagtccacctccaccaattgaa
tggcatatcagccgaccaggacagtttgaaacctttgatctcatgacacttcatccaata
gaaattgcacgtcaactgacacttttggaatctgatctctataggaaagtccaaccttct
gaactagtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgatccgccataccacaaatctcactctatggtttgaaaagtgcattgtggaagca
gaaaattttgaggaacgggtggcaatactaagtagaattatagaaattcttcaggttttt
caagatttgaataatttcaatggtgtattggagatagtcagtgcagtaaattcagtgtca
gtatacagactagaccatacttttgaggcattgcaggaaagaaaaaggagaattttggat
gacgctgtggaattaagtcaagatcactttaaaaaatacctagtaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaaaactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattacgggagaaattcagcagtatcagaatcaaccttactgtttacgg
atagaaccagaaatgaggagattctttgaaaaccttaaccccatgggaaatgcttctgaa
aaggagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaattgcaaa
cagccacctcgatttcctaggaaatcaactttctctttaaaatctcctggaatacggcct
aatacaggccgacatggctctacctcaggcactttacgaggtcatccaacaccattagaa
agagaaccatgtaaaatgagctttagtcggattgctgaaactgatcttgaatcaactgtg
tcagcaccaacctctccaaatacaccctctactccaccagtgtctgcttcttcagacctt
agtgtgtttttagatgtggatctcaatagttcctgtggcagcaatagcatttttgctcca
gtcctcttgccacattcaaagtctttcttcagttcatgtggtagtttacacaaactaagt
gaagagccactgattcctccgcctcttcctcctcgaaaaaagtttgatcatgatgcttca
aattccaagggaaatacgaaatctgatgatgacccccctgctattccaccaagacagccg
cctcctccaaaggtaaaacccagagttcctgctcctactggtacatttgatggacctctg
catagtccacctccaccaccgccaagagatcctcttcctgatacccctccaccagttccc
cttcggcctccagaacacttcataaactgtccgtttaatcttcagccacctccactagga
catcttcacagagatccagactggttcagagacgttagtacctgtccaaattcgccaaat
actcctcccagcacaccctctccgagagtaccacgtcgatgctacgtgctcagttctagt
cacaacaaccttgctcatcctcaagctcctcctgttccaccaaggcagaattcaagccct
cacctaccaaaactgccaccaaagacttataaacgggagctttcgcaccctccgtcatac
agactgcctttgctagaaaatgcagaaactcctcaatga
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