KEGG   Neogale vison (American mink): 122900866
Entry
122900866         CDS       T08764                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
nvs  Neogale vison (American mink)
Pathway
nvs01522  Endocrine resistance
nvs04010  MAPK signaling pathway
nvs04012  ErbB signaling pathway
nvs04014  Ras signaling pathway
nvs04024  cAMP signaling pathway
nvs04068  FoxO signaling pathway
nvs04071  Sphingolipid signaling pathway
nvs04137  Mitophagy - animal
nvs04140  Autophagy - animal
nvs04141  Protein processing in endoplasmic reticulum
nvs04210  Apoptosis
nvs04215  Apoptosis - multiple species
nvs04217  Necroptosis
nvs04310  Wnt signaling pathway
nvs04380  Osteoclast differentiation
nvs04510  Focal adhesion
nvs04530  Tight junction
nvs04620  Toll-like receptor signaling pathway
nvs04621  NOD-like receptor signaling pathway
nvs04622  RIG-I-like receptor signaling pathway
nvs04625  C-type lectin receptor signaling pathway
nvs04657  IL-17 signaling pathway
nvs04658  Th1 and Th2 cell differentiation
nvs04659  Th17 cell differentiation
nvs04660  T cell receptor signaling pathway
nvs04664  Fc epsilon RI signaling pathway
nvs04668  TNF signaling pathway
nvs04722  Neurotrophin signaling pathway
nvs04723  Retrograde endocannabinoid signaling
nvs04728  Dopaminergic synapse
nvs04750  Inflammatory mediator regulation of TRP channels
nvs04910  Insulin signaling pathway
nvs04912  GnRH signaling pathway
nvs04914  Progesterone-mediated oocyte maturation
nvs04917  Prolactin signaling pathway
nvs04920  Adipocytokine signaling pathway
nvs04926  Relaxin signaling pathway
nvs04930  Type II diabetes mellitus
nvs04931  Insulin resistance
nvs04932  Non-alcoholic fatty liver disease
nvs04933  AGE-RAGE signaling pathway in diabetic complications
nvs04935  Growth hormone synthesis, secretion and action
nvs04936  Alcoholic liver disease
nvs05010  Alzheimer disease
nvs05012  Parkinson disease
nvs05016  Huntington disease
nvs05017  Spinocerebellar ataxia
nvs05020  Prion disease
nvs05022  Pathways of neurodegeneration - multiple diseases
nvs05132  Salmonella infection
nvs05133  Pertussis
nvs05135  Yersinia infection
nvs05142  Chagas disease
nvs05145  Toxoplasmosis
nvs05152  Tuberculosis
nvs05161  Hepatitis B
nvs05162  Measles
nvs05166  Human T-cell leukemia virus 1 infection
nvs05167  Kaposi sarcoma-associated herpesvirus infection
nvs05169  Epstein-Barr virus infection
nvs05170  Human immunodeficiency virus 1 infection
nvs05171  Coronavirus disease - COVID-19
nvs05200  Pathways in cancer
nvs05208  Chemical carcinogenesis - reactive oxygen species
nvs05210  Colorectal cancer
nvs05212  Pancreatic cancer
nvs05231  Choline metabolism in cancer
nvs05415  Diabetic cardiomyopathy
nvs05417  Lipid and atherosclerosis
nvs05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nvs00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    122900866 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122900866 (MAPK8)
   04012 ErbB signaling pathway
    122900866 (MAPK8)
   04014 Ras signaling pathway
    122900866 (MAPK8)
   04310 Wnt signaling pathway
    122900866 (MAPK8)
   04668 TNF signaling pathway
    122900866 (MAPK8)
   04068 FoxO signaling pathway
    122900866 (MAPK8)
   04071 Sphingolipid signaling pathway
    122900866 (MAPK8)
   04024 cAMP signaling pathway
    122900866 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    122900866 (MAPK8)
   04137 Mitophagy - animal
    122900866 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    122900866 (MAPK8)
   04215 Apoptosis - multiple species
    122900866 (MAPK8)
   04217 Necroptosis
    122900866 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122900866 (MAPK8)
   04530 Tight junction
    122900866 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    122900866 (MAPK8)
   04621 NOD-like receptor signaling pathway
    122900866 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    122900866 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    122900866 (MAPK8)
   04660 T cell receptor signaling pathway
    122900866 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    122900866 (MAPK8)
   04659 Th17 cell differentiation
    122900866 (MAPK8)
   04657 IL-17 signaling pathway
    122900866 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    122900866 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    122900866 (MAPK8)
   04920 Adipocytokine signaling pathway
    122900866 (MAPK8)
   04912 GnRH signaling pathway
    122900866 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    122900866 (MAPK8)
   04917 Prolactin signaling pathway
    122900866 (MAPK8)
   04926 Relaxin signaling pathway
    122900866 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    122900866 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    122900866 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    122900866 (MAPK8)
   04722 Neurotrophin signaling pathway
    122900866 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    122900866 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    122900866 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122900866 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    122900866 (MAPK8)
   05231 Choline metabolism in cancer
    122900866 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    122900866 (MAPK8)
   05212 Pancreatic cancer
    122900866 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    122900866 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    122900866 (MAPK8)
   05161 Hepatitis B
    122900866 (MAPK8)
   05171 Coronavirus disease - COVID-19
    122900866 (MAPK8)
   05162 Measles
    122900866 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122900866 (MAPK8)
   05169 Epstein-Barr virus infection
    122900866 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    122900866 (MAPK8)
   05135 Yersinia infection
    122900866 (MAPK8)
   05133 Pertussis
    122900866 (MAPK8)
   05152 Tuberculosis
    122900866 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    122900866 (MAPK8)
   05142 Chagas disease
    122900866 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    122900866 (MAPK8)
   05012 Parkinson disease
    122900866 (MAPK8)
   05016 Huntington disease
    122900866 (MAPK8)
   05017 Spinocerebellar ataxia
    122900866 (MAPK8)
   05020 Prion disease
    122900866 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    122900866 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122900866 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    122900866 (MAPK8)
   05415 Diabetic cardiomyopathy
    122900866 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    122900866 (MAPK8)
   04936 Alcoholic liver disease
    122900866 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    122900866 (MAPK8)
   04931 Insulin resistance
    122900866 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    122900866 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    122900866 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nvs01001]
    122900866 (MAPK8)
Enzymes [BR:nvs01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     122900866 (MAPK8)
Protein kinases [BR:nvs01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   122900866 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 122900866
NCBI-ProteinID: XP_044095929
LinkDB
Position
2:199395597..199498178
AA seq 427 aa
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacagcaatttttatagtgtagagattggagattctacattt
acagtcttgaaacgatatcagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccggcca
tttcagaaccagactcatgctaaacgggcttacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggaactagatcatgagagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatcgtggtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacaccttacgtagtgactcgctactacagagcacctgaggtcatcctagggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgccctgaattcatgaagaaactacagccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccccgatgtacttttc
ccagctgactcggaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggtaattgatgcatctaaaaggatttctgtagatgaagctctccagcacccatat
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgacaag
cagttagatgaaagggaacatacaatagaagaatggaaagagttgatatacaaagaagtt
atggacttggaggagagaaccaagaatggagttataaggggacagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcatcgtctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctcagatacagacagcagtctagaagcatcagct
ggacctctgggctgctgtagatga

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