Neogale vison (American mink): 122900943
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Entry
122900943 CDS
T08764
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs00562
Inositol phosphate metabolism
nvs01100
Metabolic pathways
nvs04014
Ras signaling pathway
nvs04015
Rap1 signaling pathway
nvs04020
Calcium signaling pathway
nvs04024
cAMP signaling pathway
nvs04070
Phosphatidylinositol signaling system
nvs04919
Thyroid hormone signaling pathway
nvs04933
AGE-RAGE signaling pathway in diabetic complications
nvs05205
Proteoglycans in cancer
Module
nvs_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
122900943 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
122900943 (PLCE1)
04015 Rap1 signaling pathway
122900943 (PLCE1)
04020 Calcium signaling pathway
122900943 (PLCE1)
04070 Phosphatidylinositol signaling system
122900943 (PLCE1)
04024 cAMP signaling pathway
122900943 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
122900943 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
122900943 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
122900943 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
nvs04131
]
122900943 (PLCE1)
Enzymes [BR:
nvs01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
122900943 (PLCE1)
Membrane trafficking [BR:
nvs04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
122900943 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
122900943 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
122900943
NCBI-ProteinID:
XP_044096066
LinkDB
All DBs
Position
2:207351669..207680479
Genome browser
AA seq
2294 aa
AA seq
DB search
MTSEEMAASVLTPVTQRKVTSAPSAIDESSEKISDISVLKAHSIRQSGQTSTTAQMNKLK
EEPSGSNLPKILSIARENIVSDENSNEECWTESTPVSVENLNINQNDILTKSQCYDTCDS
VMEEDPYLETGNPSSLERKVFPGIQLEIDGPPMDISPFGSQSAIVETGQAHPDGNTAAFH
FHYEVDRRVSDTFCTLSGNLILDDCGNCVPLPDVGGEQKKNYVTYTCEFMELAENCDNKN
GQLQCDHCDTLDDKYLCFEGSCQRSSVLCSSDSLCREDLTNSPPAKTFLSHFEDFPDNCE
DVEEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGHIGLEAYSYIDQKR
SGLLLPCGRVLEQLSVVAIRQDGSQCLSEAQWYRIYNAVRSREEIENTFESLLHVFTNLP
ASEAAHERISIGPCLKQCIQDTICEYRATLQRTSISQYITGSLLEATTSLGARSGLLSTF
GGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQEQNIY
RRVLPVDYLCFLTRDLGTPECQTSLPCLKASISASILTSQNGEHNALEDLVMRFNEVSSW
VTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQSD
LETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGLMKLC
PRYNSQEETLEFVADYSGQDNFLQRVGHNGLKNSEKESTVNSIFQTIRSCSRSLEAEDED
SPSEGNSSRKNSLRDKARWQFIIGDLLDSENDIFEQSKEWDSHGSEEPQKAFDHGTELIP
WYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTASPASAKAK
LGVLSNTSEPGKFPLLGNAGLSGLAEGVLDLFSAKAVYMGHPSIDIHTVCVQNKLGSMFL
SETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQQWLRKQY
VSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPSVQRNNTLGISTTKKK
KKILIRGESGEAADDETATRKVKMQRESRSRSGSDPQDMNEQEESEANAIMSPPNTLPSR
RAHSLTTAGSPNLSAGTSSPIRPVSSPVLSSSNKSLSSAWSSSSWHGRIKGGMKGFQSFM
VSDSNMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCSRAGSESAPLYTNLTIDENTSDL
QPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGIFGVGIL
QLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLLSFEGFARFLMDKDNFASKNDES
QEDIKDLQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGT
PIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGE
KLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQAY
NGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKRI
KKADNSACNKGKIYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNASG
SSRGKERKSRKSIFGNNPGRMSPGETASFNKASGKSSCEAMRQAWEESSSPLNPTTSLSA
IIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLMFWLH
GIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDNME
PAVYSLTIVSGQNVCPNSSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFR
VHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSRR
MEENSSSSAVPASLMFNTEERKCLQTHKVTVHGVPGPEPFTVFSINGGTKAKQLLQQILT
TEQDTKPIVTDYFLMEEKFFISKEKNECRKQPFQRVIGPEEEIMQILSSWFPEEGYVGRI
VLKTQQENLEERSIIQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQ
TLCKAKYSYSILNNPNPSDYVLLEEVVKDATKKSSTPKSSQRVLLDQECVFQAQSKWKGA
GKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLTSPSQALASESVQSKEEKP
VGSLPSSDAIDYRQ
NT seq
6885 nt
NT seq
+upstream
nt +downstream
nt
atgacatcagaagaaatggcagcttctgttctcacacctgtaactcagagaaaagtgacg
tccgctccatcggctatagatgaaagtagtgaaaagatctcagacatcagtgttctgaag
gcacatagcatcaggcagagtgggcagacttctaccactgcacagatgaacaagcttaaa
gaagaaccttctggaagcaacttgcccaagattctctcaatagcaagggagaatatagtg
agcgatgagaacagcaatgaagagtgctggacagaaagcacaccagtttctgtggaaaac
cttaacattaaccaaaatgacatactgacaaagagccagtgttatgacacgtgtgattct
gtcatggaggaagacccgtatttggaaactggaaacccatcctcactggaaagaaaggtg
ttccctggaattcaactggaaattgatggacctcccatggacattagtccctttggaagt
cagtcggccatcgtagagactggccaggcacaccctgatggcaacacagcagcatttcac
tttcactatgaagttgacagaagagtgtcagatactttttgtaccctgtcaggcaacttg
attttagatgattgtggaaactgtgtaccactgcctgatgttggtggggagcaaaagaaa
aattatgtgacatatacttgtgaatttatggaattggctgaaaactgtgataataagaat
gggcagctgcagtgtgatcattgtgacaccttggatgacaaatacttatgctttgaaggt
tcttgccaaaggtccagtgtgctatgttcaagtgacagcctttgcagggaggacttgact
aacagcccccctgccaagacttttctgagccattttgaggacttccctgataactgtgaa
gatgtagaagaagatttttttaagagcaaaaaggagaggtccactttgttagtgaggaga
ttttgtaaaaatgacagggaagtaaagaaatctgtgtataccgggacaagggcaatcatg
aggactctgccttctggtcacattgggctggaagcttacagttacatcgatcagaagaga
agtggtcttttattgccctgtgggagagttctggaacagctgtcagtggtggcgattagg
caggatggaagccagtgcctatcagaagcccagtggtatcggatctacaatgcagtgaga
agcagagaagaaatagaaaatacatttgaatctcttctccatgtcttcacaaatctccca
gcctccgaggcagcccatgaaaggattagcatcggtccatgcttaaaacagtgtatccaa
gacaccatatgtgagtaccgggccaccctccagagaacgtccatatctcagtacatcacg
ggctctctcctagaagcaaccacatctttgggagcaagaagtggcctactcagtactttt
ggaggatccactggacgaatgatgctaaaagaacgccagccaggcacctccatggctaat
tccagtgccctcccttcaagttcagctgggatcagcaaggaactgattgacctccagccc
ctcattcagttcccagaggaagtcgccagcatcctgatggagcaggaacagaacatttac
cgaagggtcttgccagttgactacctttgcttcttaacccgggacttaggcactccggaa
tgccagacatccctgccctgcctcaaagcatccatctcagcttcgattcttacctcccag
aatggagagcacaatgccctggaagatctggtgatgagatttaatgaggtgagctcttgg
gtgacatggctgatcctcacagcaggctccatggaggagaagcgagaagtcttctcctat
ttggtgcatgtggccaaatgctgctggaacatgggcaactacaatgctgtcatggagttc
ttggctggcctcaggtcaaggaaagtcttaaaaatgtggcagtttatggaccagtctgac
ctggagaccatgaggagcctgaaggacgccatggctcagcacgaatcttcctgcgagtac
aggaaggtggtcacgcgggccctgcacatacctggctgtaaggtggttccgttctgtggg
gtgtttctgaaggagctctgtgaagtactggatggagcctctggcctcatgaagctttgc
ccgaggtacaattcccaagaagaaactctagagtttgtagccgattacagcggacaagat
aatttcttacaacgagtgggacataatggcttaaagaattcagagaaggagtccactgtc
aacagcatctttcagaccatcagaagctgcagccgaagtctggaggcagaggatgaagac
agccccagcgaaggcaacagctctaggaaaaattccttgagggataaagcacggtggcag
tttataattggagatctgttggattctgaaaatgacatctttgagcagtcgaaagaatgg
gactctcatggatcagaagagccacagaaggcctttgaccatggcacggagctgatcccg
tggtacgtgctgtccatccgagctgatgtgcaccagttcctactgcagggggccactgtc
atccactatgaccaggacacgcacctgtccgcccgctgcttccttcagcttcagcctgac
aacagcaccctgacctggataaagcccaccactgcctccccagccagtgctaaagcaaaa
cttggtgtgcttagtaacacatctgagcctggcaaattccccttactgggcaatgctgga
ttaagtggcctggcggagggggtcttggatctgttttcagcaaaggctgtgtacatggga
caccctagcatcgatatacacactgtgtgtgttcagaacaaactgggtagcatgtttctc
tccgagactggcgtgacactgctctatgggctccagaccacggacaatagattattgcac
tttgtggcgcccaagcacacagctaagatgctcttcagcggattgctagaactcacgagg
gctgtgaggaagatgaggaagttcccggaccagagacagcagtggctgcggaaacagtat
gtcagcctctatcaggaggacggacggtatgaaggcccaactttggctcacgctgtggag
ctgttcggtggccgacgatggagtacacgcaaccccagccccgggacatctgcgaagagt
gctgagaagcccagtgtgcagaggaacaacacgttgggcataagcaccaccaagaaaaag
aagaaaatccttatacggggtgagagtggagaggcagccgacgacgagacggccacgcgg
aaggtcaaaatgcagagggagagtcgcagtcggagtggttcagaccctcaagacatgaat
gagcaagaagaatccgaggcaaatgccatcatgagccctcctaacactctgccttccaga
agagcccactccttgaccacggctgggtcccccaacttgtctgctgggacatcatctccc
atcaggccagtgtcttcccctgtgctgtcttcttcaaacaagagcctgtccagtgcttgg
agcagcagcagctggcacgggaggatcaaaggaggaatgaagggttttcagagcttcatg
gtttccgacagtaacatgagtttcgttgaatttgttgagctgttcaaatcattcagcgtg
aggagccgcaaggacctcaaggatctctttgacatctacgccgtgccctgcagccgcgcc
ggctccgagtcagcccctctctacaccaacctaaccatcgacgaaaacaccagtgatctt
cagcctgacctagatttactgaccagaaatgtctcggacttggggttgttcattaagagt
aaacagcagctgtcagacaaccagaggcagatatctgatgccattgctgctgcgagtatc
gtgactaatggcactggggtcgagagcacgtctctaggcatctttggggtcggcatactc
cagctcaatgacttcctcgtcaactgtcagggagagcactgcacttacgatgaaatcctc
agtatcattcagaagttcgagcctagcattagtatgtgtcatcagggcctactgtcattt
gagggatttgcaaggtttctgatggataaagataattttgcctccaaaaatgacgagtca
caggaagacattaaagacttgcagctgcccctgtcctactattacattgaatcttcacac
aatacctacctcacaggccaccagctcaaaggagagtcctcagtggaactctacagtcag
gtcctcctacaaggctgcaggagtgtagagttggactgctgggatggagatgatgggacg
cccatcatctaccacgggcacacgctgacaacgaagatccccttcaaggaggtggttgaa
gccattgaccgcagtgccttcatcaactctgacctgcccatcatcatatcaattgagaac
cactgctcattgcctcagcaacgaaaaatggcagaaattttcaagactgtgtttggagaa
aaactggtggccaaattcctgtttgagagcgatttctcagatgatccaatgcttccctca
cctgaccaacttaggaggaaagtacttcttaaaaataagaagctaaaagctcaccagacg
ccagtggatatcttaaagcaaaaggctcatcagttagcatccatgcaagctcaggcttat
aatggggggaatgccaaccccccacctgctaataacgaggaagaagaggatgaagaggat
gaatatgattatgactatgaatctctgtctgatgacaacattctagaagacagacctgaa
aataaatcatgtaatgacaagcttcagtttgagtataatgaagaaatccccaagaggata
aagaaagcagacaactctgcctgcaacaaaggaaagatttatgacatggaattgggagaa
gaattttatcttcctcagaataaaaaggaaagcagacagattgcaccagagctttctgac
cttgtcatctattgccaagctgtaaaatttccaggcctgtcaactctaaatgcatctggc
tctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggcaga
atgagccctggggagacagcatcgtttaacaaagcatctggaaaaagttcctgtgaagca
atgcggcaggcctgggaggaatcttcttcccccctgaacccaaccacatccctcagcgct
atcattagaactcccaaatgttaccatatctcatcgctgaatgaaaatgccgccaaacgt
ctgtgtcgcaggtattctcagaaactgatccagcacaccgcctgtcagctgctgaggact
tacccggctgccacccgcatcgactcctccaaccccaatcccctcatgttctggctccat
gggatacagctcgtggcgctcaactaccagacagatgatctccccttacatttaaatgct
gccatgtttgaggccaacggtggctgtggctatgttctgaaacccccagttctgtgggac
aagaactgtcccatgtaccaaaagttttcacccttggaaagagacttggacaacatggag
cctgccgtctattccttaactatcgtctctggtcaaaacgtgtgtccaaacagcagcacg
gggagcccgtgcatcgaagtcgacgtcctgggcatgcccctggacagctgccacttccgc
acaaagcccatccaccggaacactctgaaccccatgtggaacgaacagtttctcttccgg
gttcactttgaagacctcatatttcttcgttttgcggttgtggaaaacaacagctcggct
gtaaccgctcagagaatcatcccactcaaggctttaaaacgaggttatcggcatcttcag
ctgcgaaacctccacaatgaagtcttggaaatctctagtttattcataaacagcagaagg
atggaagaaaattcctccagcagtgctgtgccggcctctttgatgtttaatacagaagaa
agaaaatgtttacagactcacaaagtcacagtgcatggggtcccaggtccagagcccttt
actgttttctccataaatggtggcaccaaggcaaagcaacttctccaacaaattctgacg
actgaacaagacaccaaacctattgtcacagactattttttgatggaagaaaaatttttt
atatctaaggaaaagaatgaatgcaggaaacaaccattccaaagagtcattggtccagaa
gaagagatcatgcagattttaagcagctggtttccagaggaaggctatgttggcaggatt
gtcttaaaaacccagcaggaaaacctagaagagagaagcattattcaagatgacaaggag
gtgatcttgagctcagaggaggagagtttctttgtccaagtgcatgatgtttctccagag
caacctcgaacggtcatcaaagcaccccgtgtcagcaccgcacaggatgtcattcagcag
accttatgcaaagccaaatattcctatagcatcctgaacaaccccaacccgagtgactat
gtgcttttggaagaggtggtgaaagatgctaccaagaagtcttctaccccgaagtcctcc
cagagggttcttttggatcaggagtgtgtgtttcaagcccagagcaagtggaaaggtgca
ggaaaattcatccttaagctaaaggagcaggttcaggcatccagagaagacaaaagaaaa
ggcatttcttttgcaagtgaattcaagaagttcaccaagtcaactaaacagccccgagga
ctcacatcaccttctcaggccttggcctcagaaagtgtccaaagcaaggaggagaaacca
gtgggcagcttgccctccagtgacgccatagactaccgacaataa
DBGET
integrated database retrieval system
