Neogale vison (American mink): 122902662
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Entry
122902662 CDS
T08764
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs00230
Purine metabolism
nvs01100
Metabolic pathways
nvs04024
cAMP signaling pathway
nvs05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122902662 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
122902662 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122902662 (PDE10A)
Enzymes [BR:
nvs01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
122902662 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
122902662 (PDE10A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
122902662
NCBI-ProteinID:
XP_044098435
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All DBs
Position
1:3195263..3529510
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AA seq
1065 aa
AA seq
DB search
MASPVEPLAPRPHAPLPAAGDEPGSGPGKLRPEPWRGVAGGGSAVGPGRAPEPTGKGRAE
RAAPPRPPLSSAGRASPAGGPGALCARGSGGWGSARAPFALALSSPVPSSSPSSFYFWPP
PPPPPPSLLPSSSAFHLPVRLPGREGAAAAAAARGGGGGGDAGGGGGGGGGQEAAPLSVP
PSSSPRGGGGSGGGRRRLFLCSALQGLLLPARAGLRLPLGPAARRAGSPGFPGAGGGCPG
PSPGGGGRTPRRPGGAGFALAAASPLLFGSDMEDGPSNNASCFRRLTECFLSPSLTDEKV
KAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKPEDESAPKEVSRYQDTNMQGVVYELN
SYIEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCVFTPPGIKEGKPRL
IPAGPIAQGTTTSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGD
LIGVLELYRHWGKEAFCMSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKT
YFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPIFKKT
KEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVI
GVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHS
ICTAEEWQDLMRFSLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLC
RFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHGLFTDLERKGLLIACLCHDLDHRG
FSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKA
IIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTA
NDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQIFPPTE
PLLKACRNNLSQWEKVIRGEESAVWISSQPAALGPSEKLPVRADD
NT seq
3198 nt
NT seq
+upstream
nt +downstream
nt
atggccagccccgtagagccgctcgctccccgcccccacgcccccctgccagcggccggg
gacgagcccggatccggccccggcaaactccgcccggagccctggcgcggcgttgcgggc
ggggggagcgcggtgggcccgggtcgggccccggagcctaccggcaaaggccgggccgag
cgcgccgcgcccccgcgcccgcccctctcctccgcaggccgcgccagccccgcggggggc
ccgggcgccctgtgtgcgcgcggcagcggcggctggggctcggcccgcgctcccttcgcg
ctcgccctctcctcccctgtcccctcctcctctccatcttccttttacttctggccgccg
ccccccccgccccctccttctcttctcccctcctcgtctgcctttcacctccccgtgcgt
ctcccaggaagggagggcgcagcggcggcggcggcggctcgaggaggaggaggcggcggc
gatgctggcggcggcggcggcggaggaggaggacaagaggcagctcccttgagcgtccct
cccagcagtagtccccgcggcggcggtggcagcggcggcgggcggcggcggctcttcctc
tgctccgcgctccagggtttgctgctcccagcccgcgccgggctccggctcccgctcggc
ccggccgcccgccgcgcgggctcccccggcttcccgggtgccggcgggggctgccccggc
cccagtccaggcggcggcggccgaactccgcggcggcccggaggcgccggcttcgccctc
gccgccgcgtcccccctgctcttcggctccgacatggaagatggaccttctaacaacgcg
agctgcttccgaaggttgacggagtgtttcctgagccccagtttgacagatgaaaaagtg
aaggcgtatctttctctccatccccaggtgttggatgagtttgtatctgaaagtgttagt
gcagagactgtagaaaaatggctgaagaggaaaaacaacaaaccagaagatgagtcggct
cctaaggaagtcagcaggtaccaagacacgaatatgcagggagttgtgtatgaactcaac
agctacatagaacagcggttggatacaggaggagacaaccagctactcctctatgaattg
agtagcatcattaaaatagccacaaaagctgatggatttgcactgtatttccttggagag
tgcaataatagtctgtgcgtcttcactccacctggaatcaaagaaggaaaaccccggctc
atccctgctgggcccattgcccagggaaccaccacctctgcctacgtggccaagtccaga
aaaacattgctagtggaggacatccttggggatgagcgatttccgagaggtactggactg
gagtcggggactcgcatccagtcggtgctctgtttgccgattgtcactgccattggcgat
ttgatcggcgtcctcgagctgtatcggcactggggcaaagaagccttctgtatgagccac
caggaggtcgcgacagccaatctcgcctgggcttcagtagcaatacatcaggtgcaggta
tgcagaggccttgctaaacagacagaactgaatgacttcctacttgatgtgtccaagaca
tattttgataacatagtcgcaatagactctctacttgaacacataatgatatatgccaaa
aatctggtgaatgcggaccgctgtgcacttttccaggtagatcataagaacaaggagtta
tattcagacctttttgatattggagaggaaaaggaaggaaaacccatcttcaagaagacc
aaagagataagattttcaattgagaaaggaattgccggtcaggtagcaagaacaggggaa
gtcctgaacattccagatgcctatgcagacccacgcttcaacagggaagtggacttgtac
acggggtacacgacccggaatatcctgtgcatgcccatcgtgagccgaggcagcgtgatc
ggcgtggtgcagatggtgaacaagatcagcggcagtgccttctcgaaaacggacgagaac
aacttcaagatgttcgccgtcttctgtgctttagccttacactgtgccaatatgtaccac
cgaatccgccattccgagtgcatctaccgggtgacgatggagaagctgtcctaccacagc
atctgcacggccgaggagtggcaggacctcatgcgcttcagcctgcccgtgcgcctctgc
aaggagatcgaactattccactttgacattggtccttttgaaaacatgtggcctggaatt
tttgtgtacatggtccatcggtcctgtgggacctcctgctttgagcttgaaaagttgtgt
cgcttcatcatgtctgtgaagaagaactaccggcgggtgccgtaccacaactggaagcac
gccgtcaccgtggcacactgcatgtacgccatcctgcagaacaaccacgggctcttcacc
gacctggagcgcaaaggactgctgatcgcgtgcctgtgtcatgacctggaccaccgaggc
ttcagcaacagctacctgcagaagttcgaccaccccctggcggctctctactccacgtcc
accatggagcagcaccacttctcccagaccgtgtccatcctccagttggaagggcacaat
atcttctccaccctgagctccagtgaatatgaacaggtgcttgagatcatccgcaaagcc
atcattgccacagaccttgctctgtactttggaaacaggaaacagttggaagagatgtac
cagaccggatcgctaaaccttaataatcaatcacatagagatcgtgtcattggtctgatg
atgactgcctgtgatctttgctctgtaacaaaactatggccggttacaaaattgacagca
aatgatatatatgcagagttctgggctgagggtgatgagatgaagaagctgggaatacag
cctattcccatgatggacagagacaagaaggatgaggtcccacaaggccagctgggcttc
tacaacgccgtggccatcccctgctacacgacgctcacgcagatcttcccgcccacagag
ccgctcctcaaagcctgcaggaacaacctcagccagtgggagaaggtgatccgaggggag
gagagcgccgtgtggatctcctcccagcccgcggccctcgggccctcggagaagctgccc
gtgagggccgacgactga
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