Neogale vison (American mink): 122906080
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Entry
122906080 CDS
T08764
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs04140
Autophagy - animal
nvs04141
Protein processing in endoplasmic reticulum
nvs04210
Apoptosis
nvs04932
Non-alcoholic fatty liver disease
nvs05010
Alzheimer disease
nvs05012
Parkinson disease
nvs05014
Amyotrophic lateral sclerosis
nvs05016
Huntington disease
nvs05017
Spinocerebellar ataxia
nvs05022
Pathways of neurodegeneration - multiple diseases
nvs05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
122906080 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
122906080 (ERN1)
09143 Cell growth and death
04210 Apoptosis
122906080 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
122906080 (ERN1)
05012 Parkinson disease
122906080 (ERN1)
05014 Amyotrophic lateral sclerosis
122906080 (ERN1)
05016 Huntington disease
122906080 (ERN1)
05017 Spinocerebellar ataxia
122906080 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
122906080 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122906080 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
122906080 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nvs01001
]
122906080 (ERN1)
Enzymes [BR:
nvs01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
122906080 (ERN1)
Protein kinases [BR:
nvs01001
]
Serine/threonine kinases: Other
IRE family
122906080 (ERN1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
122906080
NCBI-ProteinID:
XP_044103571
LinkDB
All DBs
Position
5:14589119..14666939
Genome browser
AA seq
975 aa
AA seq
DB search
MPARLLLVLLALLLPGPGILGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSEGILYMGK
KQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF
DYAASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLKKV
LHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HDGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDVNFDPGLKGKNKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTISQ
DVEEKYERAPAKPEAPMDSVLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQ
KELEKIQLLQQQQLPFHPPGDVAQDAEPLDSSGLYSESSGTSSPSTSPRASNHSLHSSGS
ASRPGSGPFPEQDDDDEETNMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCLHPEKHEDVIARELIENMIAMEPQKRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLR
AMRNKKHHYRELPTEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMEPCGHERLFQPYYF
HEPPEPWPPVTADTP
NT seq
2928 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggctgctgctggtgctgctggcgctgctgctgcctggccccgggattttg
ggaagtcccagcacagtgacgcttcctgaaaccttgttgtttgtgtcaactctggatgga
agtttgcatgctgtcagcaagaggacaggctcgatcaaatggactttaaaagaagatcca
gttctgcaagttccaacacatgtggaagagcctgccttcctcccagatcccaatgacggc
agcctgtatacgcttgggggcaagaataatgaaggcctgacgaaacttccttttaccatc
ccagagttggtacaggcatccccatgccgaagttcagaaggaattctctacatgggtaaa
aagcaggacatttggtacgtcattgaccttctgaccggggagaagcagcagactctgtcg
tcagcctttgcagacagtctctgcccatcaacctctttgctgtatcttggccgaacagaa
tacaccatcaccatgtacgacaccaaaacccgtgagctccgatggaacgccacctacttc
gactacgcagcctcgctgcctgaggacgacggggactacaagatgtcccactttgtgtct
aatggcgatgggctggtggtgaccgtggacagtgaatctggcgacgtcctatggatccaa
aactacgcttcccccgtggtggccttttacgtctggcagcgggagggtctgaagaaggtg
ctgcacatcaatgtcgctgtggagaccctgcgctacctgaccttcatgtccggggaggtg
ggccgcatcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctg
acgcccacgctgtatgtcgggaagtactctaccagcctgtatgcctccccctccatggtt
cacgacggagtcgccgttgtgccccgaggcagcactctgcctttgctggaaggcccccag
actgatggggtcaccatcggggacaaaggggagtgtgtgatcacgcccagcacagacgtc
aactttgaccctgggctcaaaggcaagaacaagctcaactacctgaggaactactggctt
ctgataggacaccatgaaacccccctgtccgcgtctaccaagatgctggagagattcccc
aacaacctgcccaaacatcgggaaaacgtgattcctgccgactcagagaagaagagcttc
gaggaagttatcaacctggttgaccagacttcagaaaacgcgcctaccaccatctcacag
gatgtggaagagaaatacgagcgtgccccagccaagcctgaggcccccatggactctgtg
ctcaaggacatcgccaccatcatcctgagcaccttcctgctcatcggctgggtggccttc
atcatcacctaccccttgagcatgcatcagcagcagcagctccagcaccagcagttccag
aaggaactagagaaaatccagctcctgcaacagcagcagctgcccttccatccacctgga
gacgtggctcaggatgctgagcccttggactcgtccggcctgtactccgagagctcgggc
accagcagcccgagcacgtcccccagagcctccaaccactcgctgcactccagtggctct
gcctccaggcctggcagcggccccttcccggagcaggacgatgacgatgaggaaaccaac
atggtgatagttgggaagatttcattctgtcccaaggacgtgctgggtcacggagctgag
ggcacgattgtgtaccggggcatgtttgacaaccgtgacgtggccgtcaagaggatcctc
cccgagtgtttcagtttcgcggaccgtgaggtccagctgcttcgagaatccgatgagcac
cccaacgtgatccgctacttctgcacagagagggaccgacagttccagtacattgccatc
gagctgtgcgccgccaccctgcaggagtacgtggagcagaaggactttgcgcacctcggc
ctggagcccatcaccctgctgcagcagaccacctcgggcctggcgcatctgcactccctc
aacattgttcacagagacctgaagccccacaacattctcctctccatgcccaacgcacat
ggcaggatcaaggccatgatctcggacttcggcctgtgcaagaagctggccgtaggcagg
cacagtttcagccgccgctcaggagtgccgggcacggaaggctggattgccccagagatg
ctgagcgaagactgcaaggacaaccctacctacacggtggacatcttctctgcgggctgt
gtcttttactacgtgatatcggagggcagccacccttttggcaagtccctgcagcggcag
gccaacatcctcctgggagcctacagcctggactgcctgcaccctgagaagcacgaagac
gtcattgcccgggaattaatagagaacatgatcgctatggagcctcagaagcgcccgtcc
gcgaaacacgtgctgaagcacccgttcttctggagcctggagaagcagctgcagttcttc
caggacgtgagtgaccgaatagaaaaggagtccctggacggcccgatagtgaagcagctg
gagcgaggcgggagagccgtggtgaagatggactggagggagaacatcaccgtccccctg
cagacagatctgcggaaattcaggacctataaaggcggctccgtccgagacctcctccga
gccatgagaaacaagaagcaccactaccgggagctccccacggaggtgcgggagacgctg
ggctccctccccgacgacttcgtgcgctacttcacgtcccgcttcccccacctcctctcc
cacacctaccgggccatggagccgtgcggccacgagcggctcttccagccctactacttc
cacgagcccccagagccctggcctccagtgactgcagacaccccttga
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