Neogale vison (American mink): 122908323
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Entry
122908323 CDS
T08764
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs00230
Purine metabolism
nvs00670
One carbon pool by folate
nvs01100
Metabolic pathways
nvs01523
Antifolate resistance
Module
nvs_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122908323 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
122908323 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
122908323 (GART)
Enzymes [BR:
nvs01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
122908323 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
122908323 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
122908323 (GART)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_3
ATP-grasp_2
ATP-grasp_4
Dala_Dala_lig_C
RimK
Sacchrp_dh_NADP
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
122908323
NCBI-ProteinID:
XP_044106921
UniProt:
A0A8C7ELT5
LinkDB
All DBs
Position
6:11246533..11280829
Genome browser
AA seq
1009 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSNHVKHVLVAPGNAGTSSLEKISNTAISINDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGNLTSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWRAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSKEEACRAVQEIMQDKAF
GAAGETIVIEEFLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPAP
QVSKDLFLKIKNTILQRTVDGMQQEGTPYTGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPIWLENCAAVTVVMASKGYPGDYTKGVEITGFPAA
QALGLEVFHAGTALKDGSVVTNGGRVLTVTAIRENLILALEEAKKGLAALKFEGAVYRKD
IGYRAIAFLQQPRGLTYKESGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLNTTEAVVAGIARACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDIVIGVASSGLHSNGFSLVRKIVAKSSLQYSSPAPEGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRVPRIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSKDLAEQILRDIKQHKEEAWVIGKVVACPEGSPRVKVKN
LIETMKINGSLLENGTVKNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSCAHIVVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKSRVEFDTAIDQVLEEYSTDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQALEAGVTVTGCTVHFVAEDVDAGQIILQES
VPVKRGDSVATLSERVKLAEHKIFPAALQLVASGAVRLGENGKICWVAE
NT seq
3030 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaattggcagcggtggaagggaacacacactggcctggaaa
cttgcacagtctaatcatgtcaaacatgtgttggttgccccaggaaatgcaggcacttcc
tccctggaaaagatttcaaatactgccatctcaatcaatgaccacacagcccttgctcag
ttctgcaaagatgagaaaattgaattcgtagttgttggaccagaggcacctctggctgct
ggaattgttggaaacctgacgtctgcaggagtccaatgctttggtcccactgcagaagca
gctcagttagagtccagcaagagattcgccaaagagtttatggaccgacatggaatccca
actgcacggtggagagctttcaccaaacctgaagaagcctgcagctttataatgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcagctggaaaaggagtgattgtt
gccaagagcaaggaggaggcctgcagggctgtacaggagatcatgcaggacaaagctttt
ggagcagctggagaaacaattgtcattgaagaatttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggaaggaccgtggcccccatgcccccagcacaagaccataagcga
ctgctggaaggagatcatggccccaacacagggggaatgggagcctattgtccagcacct
caggtttctaaggatttgttcctgaaaataaaaaatactattcttcagaggacagtggac
ggcatgcagcaggagggcacgccatacacaggtgttctctatgctggtataatgctgacc
aaggatggcccaaaagttctggagttcaattgccgtttcggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgattcagtctaccttggatggcctg
ctctgtacatctctgcctatttggcttgaaaactgcgctgcagtaactgtcgtaatggca
agtaaaggctatccgggagattacaccaagggtgtggagataacagggtttcctgcggct
caagctttaggactggaggtcttccacgcaggcactgctctgaaagatggcagcgtggtg
actaacgggggtagagtccttacggtaacagcgatccgggaaaatctcatcttggccctt
gaagaagccaaaaaaggactagctgctctaaagtttgagggagccgtttacaggaaggac
ataggctatcgcgccatagcttttctccagcagcccaggggcctgacttacaaggaatct
ggggtagacattgcagctggaaatatgctggtcaagaaaattaaacctttagcaaaagct
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcaagtggaacagatggtgttggaactaaactg
aagattgcccagcagtgtaacaaacatgataccattggtcaagatctggttgcaatgtgt
gtcaatgacattctggcccaaggggcagagccccttttcttcctcgattacttttcctgt
ggaaaacttgaccttaatacaactgaagctgttgtcgctggaatcgccagagcctgtgga
aaagctggatgtgctctccttggaggtgaaactgcagaaatgcccgacatgtatcctccg
ggagaatatgacctagctggttttgccgttggtgccatggagcgggatcagaaactccct
cacctggaaagaatcactgaaggggatattgttattggagtagcttcatctggtcttcac
agcaatggatttagccttgtaaggaaaattgtggcaaaatcttccctccagtactcctct
ccagcacctgaaggctgtggtgatcagaccttaggggacttacttcttactccaaccaga
atctacagccattcactgctacctgtcctacgttcaggacacgtcaaggcctttgcccat
attaccggtggaggattgctagaaaacatccccagagtccttcctcagaagtttggggtg
gatttagatgcccagacctggagggtccccaggatcttctcatggttacagcaggaagga
cacctctctgaggaagaaatggccagaacatttaactgtgggattggggctgccctcgtg
gtgtcaaaggatctggcagagcagattctgagagatattaagcagcacaaggaggaagcc
tgggtgattggcaaggtggtggcatgtcccgaaggttctcctcgtgtgaaagtcaagaat
ttgatagaaaccatgaaaataaatggatcactattggaaaatggcactgtgaaaaatcat
ttctctgtccaaccaaaaaaggcaagagtggctgtcttaatatctggaacaggatcaaac
ctgcaagctctcatagacagcactagggagccaagtagctgtgcgcacatagtcgttgtt
atctccaacaaagccgcagtggctggcttagataaagcggagagagctggaattcccacc
agagtaattaatcataaattatataaaagtcgggtagaatttgacactgcaattgaccaa
gtccttgaagagtactccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcaggaaatgggatgggaagatgctcaacatccacccatccttgctcccg
tctttcaagggttcaaatgcccacgagcaagccctagaagccggcgtcacagtcaccggg
tgtaccgtgcactttgtagctgaagatgtagatgctggacagattattttacaagaatct
gttccagtgaagagaggtgacagtgttgcaactctgtctgaaagagtgaaattagcagag
cacaaaatattccccgcagccctccagctggtagccagtggagctgtacggcttggagaa
aatggcaagatttgctgggtcgcagagtga
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