KEGG   Neogale vison (American mink): 122909088
Entry
122909088         CDS       T08764                                 
Symbol
MLH1
Name
(RefSeq) DNA mismatch repair protein Mlh1 isoform X1
  KO
K08734  DNA mismatch repair protein MLH1
Organism
nvs  Neogale vison (American mink)
Pathway
nvs01524  Platinum drug resistance
nvs03430  Mismatch repair
nvs03460  Fanconi anemia pathway
nvs05200  Pathways in cancer
nvs05210  Colorectal cancer
nvs05213  Endometrial cancer
nvs05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:nvs00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03430 Mismatch repair
    122909088 (MLH1)
   03460 Fanconi anemia pathway
    122909088 (MLH1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122909088 (MLH1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    122909088 (MLH1)
   05226 Gastric cancer
    122909088 (MLH1)
   05213 Endometrial cancer
    122909088 (MLH1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    122909088 (MLH1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:nvs03400]
    122909088 (MLH1)
DNA repair and recombination proteins [BR:nvs03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   MMR (mismatch excision repair)
    MutL homologs
     122909088 (MLH1)
SSDB
Motif
Pfam: Mlh1_C DNA_mis_repair HATPase_c_3 HATPase_c
Other DBs
NCBI-GeneID: 122909088
NCBI-ProteinID: XP_044108639
LinkDB
Position
6:complement(158161595..158219789)
AA seq 758 aa
MSLVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVVVKEGGLKLIQ
IQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTA
DAKCAYRANYSDGKLKAPPKPCAGNQGTQITVEDLFYNISTRRKALKNASEEYGKILEVV
GRYSIHNSGISFSVKKQGETVADVRTLPNATTVDNIRSIFGNAVSRELIEVGCEDKTLAF
KMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISP
QNVDVNVHPTKHEVHFLHEDSILERVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEVV
KSTTGVTPSSASGSGDKVYAHQMVRTDSREQKLDAFLQPLSKALSSQPEAIVPQDRTDAS
SGRPGQQDEEMLELPEPAQASATNQGTEEDATEGPSKTSERRGPPFSLGNPRKRPRESSD
VEMAEDDSRKEVTAACTPRRRIINLTSVLSLQEEINARGHETLREMLQNHSFVGCVNPQW
ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWT
EEDGPKEGLAEYIVEFLKKKAEMLTDYFSLEIDEEGNLTGLPLLIDNYVPPLEGLPIFIL
RLATEVNWDEEKECFESLSKECAMFYSIRKQYVSEESTLSGQQGEVSGSSANPWKRTVEH
VVYKAFRSHLLPPRHFTEDGNILQLANLPDLYKVFERC
NT seq 2277 nt   +upstreamnt  +downstreamnt
atgtcgcttgtagcgggggttattcggcggttggacgagacagtggtgaaccgcatcgcg
gcaggggaagttatccagcggcccgctaatgccatcaaggagatgattgagaactgttta
gatgcaaaatccaccagtatccaagtggttgttaaagagggaggcctcaagttaattcag
atccaagacaatggcactgggatcaggaaggaagatctggacattgtgtgtgagaggttc
actacaagtaaactgcagtcctttgaggatttagctagtatttctacctatggctttcgg
ggtgaggctttggcaagcatcagccacgtggctcatgttactattacgaccaaaacagct
gatgcaaagtgcgcgtacagagcaaattactcagatggaaagctgaaagctcctcctaaa
ccatgtgcaggcaatcaggggacccagatcacagtggaagaccttttttacaacatatcc
acaaggaggaaagctttaaaaaatgcaagtgaagagtatgggaaaattttggaagttgtt
ggcaggtattcaatacacaattcaggcattagtttctcagttaaaaaacaaggtgagacc
gtggctgacgttaggacactgcccaatgccacaacggtggacaatattcgctccatcttt
ggaaatgctgttagccgagaactgatagaagttgggtgtgaggataaaaccctggccttc
aaaatgaatggctacatatccaatgcaaattactcggtgaagaagtgcatcttcttactc
ttcatcaaccatcgtctggtagagtcaacttctttaagaaaagccattgaaacagtgtat
gccgcatatttgcccaaaaacacacacccattcctgtacctcagtttagagatcagcccc
cagaatgtggacgtcaacgtgcaccccacaaagcacgaagttcacttcctacatgaggac
agcatcctggagcgggtgcagcagcacattgagagtaagctcctgggctctaattcctcc
agaatgtacttcacccagactttactaccaggtcttgctggcccctctggagaggtggtt
aaatccacaacaggtgtgaccccctcatctgcttctggaagtggcgacaaggtctatgcc
caccagatggtccgcacagattcacgggaacagaagcttgatgcctttctgcaacccctg
agcaaggctctgtccagtcagcctgaggccattgttccacaagacaggaccgatgcttcc
agtggcaggcctggacagcaagatgaggaaatgcttgaactcccagagcctgctcaagcg
tctgccacaaatcagggcacagaggaagatgcaacagaggggccttcaaaaacatcagag
aggagagggccccctttcagcctgggcaaccccagaaagaggccccgggaaagctctgat
gtggaaatggcggaagatgattcccgaaaggaagtgacagcagcatgtacccctcggcgg
aggatcatcaacctcaccagtgtgctgagcctccaggaagaaattaacgcacggggacat
gagacacttcgagagatgctgcagaaccactcctttgtgggctgtgtgaatccgcagtgg
gccttggcacagcatcagaccaagttataccttctcaacaccaccaaactgagtgaagaa
ctgttctaccagatactcatttatgattttgccaattttggtgttctcaggctctcggag
ccagcaccactgtttgacctggccatgctagccttggatagtcctgagagtggctggacg
gaggaagatggtcccaaagaaggacttgctgagtacattgttgagtttctgaagaagaag
gctgagatgctcacagactatttctctttggaaatcgatgaggaagggaacctgactgga
ttgcccctgctgatcgacaactatgtgcctccattggagggtctccctatcttcattctt
cgactagccacggaggtgaactgggatgaagagaaggaatgttttgaaagcctcagtaaa
gaatgtgctatgttttactccattcggaagcagtacgtatctgaggagtcgaccctctcg
ggccagcagggggaagtgtccggctcctctgcaaacccctggaagcggactgtggaacat
gttgtctataaagccttccgctcacaccttctgcctcctagacatttcacagaagatgga
aatatcctacagcttgctaacctgcccgatctgtacaaagtcttcgagaggtgctaa

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