Neogale vison (American mink): 122909733
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Entry
122909733 CDS
T08764
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs00230
Purine metabolism
nvs01100
Metabolic pathways
nvs04024
cAMP signaling pathway
nvs04928
Parathyroid hormone synthesis, secretion and action
nvs05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122909733 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
122909733 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
122909733 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122909733 (PDE4A)
Enzymes [BR:
nvs01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
122909733 (PDE4A)
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GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
122909733
NCBI-ProteinID:
XP_044110157
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Position
6:complement(216855830..216894696)
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AA seq
871 aa
AA seq
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MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERS
PHRPIERADAVDTGDRPGLRTSRMSWPSSFHGTGTGSGGASGGSCRRFEAENGPSPSPGR
SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
SSPTMKDREKQPAPRQRPSQQPPPPGPQFQPMSQITGVKKLRHSSSLNDSSIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYML
TLEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPDEEPRGPGHPPPPDKFQFELTLEEEEEEE
VSTAPGAFEVRDLTMAQDPSLAEEPWEVDGHVLPTEVKVEEPGVTQQGDTAHSVATGEDG
AMFPDASVEAGGRSSPLALSTESPPLPSLRTPPSPEEAPGLQGLPSVAAEVGAQKEHQAA
KRACSACTGTSGEEPTPLPAPGGWGSAGGPT
NT seq
2616 nt
NT seq
+upstream
nt +downstream
nt
atggagcccccggccgccccctcggagaggagcctgtctctgtctctgcccgggccccgg
gagggccaggccaccctgaagccgcccccccagcacctgtggcggcagccgcggaccccc
attcgtatccagcagcgcggctactccgacagcgcggagcgcgcagagcccgagcggtcg
ccacaccggcccatagagcgcgccgacgccgtggacaccggcgaccggcccggcctgcgc
acttcccgcatgtcctggccctcgtccttccacggtaccggcaccggcagcggcggcgcg
agcggaggcagctgcaggcgctttgaggcagagaatgggccctcgccgtctcccggccgc
agccccctggactcgcaggcgagcccgggcctcgtgttgcatgctggggccgccaccagc
cagcgccgggagtccttcctgtaccgctcagacagcgactacgacatgtcccccaaaact
atgtcccggaactcgtcggtcaccagcgaggcgcacgctgaggacctcattgtgacacct
tttgcccaggtgctggccagtctccggagtgttcgcagcaacttctcactcctgaccaat
gtacccattcccagcaacaaacggtccccattgggcggcccaaccccagtctgcaaggcc
acgctatcagaagagacatgtcagcaactggcccgggagacactggaggagctggactgg
tgtctcgaacagctggagaccatgcagacataccgctccgtgagcgagatggcttctcac
aagttcaagaggatgttaaaccgtgaactcacacacctgtcagagatgagcaggtcagga
aaccaggtctctgagtacatctccaccacattcctggacaagcagaatgaagtggagatc
tcatcgcccacaatgaaggatcgagaaaaacagccagccccacggcagagaccctcccag
cagcccccgcccccagggccacagttccagcctatgtctcagatcacaggggtgaagaag
ttgagacacagcagcagcctgaatgactccagcatcccccgctttggggtaaagaccgac
caagaggagctcctggcccaagaactggagaacctgaacaagtggggcctgaacatcttt
tgcgtgtcggaatatgcgggcggccgctccctcagctgcatcatgtacacgatatttcag
gagcgggacttgctaaagaagtttcgcatcccagtggacaccatggtgacttacatgctg
accctggaggaccactaccaccccgatgtggcctaccacaacagcctgcacgcggctgat
gtgctgcagtccacacacgtgctgctggccacgcccgcgctcgatgctgtgttcacggac
ctggagattcttgccgccctctttgcagctgccattcatgacgtggaccaccctggggtc
tccaaccagttcctcatcaacaccaattcggagctggcgctcatgtacaacgacgagtcg
gtgctggagaaccaccacctggccgtgggcttcaagctgctgcaggaagataactgcgac
atcttccagaatctcagcaagcgccagcggcagagcctgcgcaagatggtcatcgacatg
gtgctggccacggacatgtccaaacacatgaccctcctggctgacctgaagaccatggtg
gagaccaagaaagtgaccagctcgggtgtcctcctgctggacaactactccgaccgcatc
caggtccttcgcaacatggtgcactgtgcggacctcagcaaccccaccaaaccactggag
ctgtaccgacagtggacggaccgcatcatggctgagttcttccagcagggcgaccgggag
cgggagcggggcatggagatcagccctatgtgtgacaagcacacagcctcggtggagaag
tctcaggtgggtttcattgactatattgtacacccgctgtgggagacgtgggcagacctg
gtccacccagatgcccaggagatcctggacacgttggaggacaatcgggactggtactac
agcgccattcggcagagcccttccccgccacctgacgaggagcccagagggccaggccac
ccacccccaccggacaagttccagtttgagctgactctggaggaggaagaggaagaggag
gtgtctaccgccccaggtgcatttgaagtgcgggacttgaccatggctcaggatccatcc
ctggctgaggaaccgtgggaggtggatggccacgtcctgcccacagaggtgaaggtagag
gaacctggcgtcacacagcaaggcgacacagcacatagtgtggctacgggcgaggacggg
gccatgttcccagacgcatccgtggaggctgggggccgcagcagccccctggccctgtcc
actgagagcccccctctgccttccttgaggaccccgccctctccagaggaagccccgggc
ctccagggcctcccctccgtggcggccgaggtgggggcccaaaaagagcaccaggctgcc
aagagggcatgcagtgcctgcacgggaacatctggcgaggagcccaccccactcccagct
cctggtgggtgggggtcagctggaggtcctacctga
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