Neogale vison (American mink): 122909735
Help
Entry
122909735 CDS
T08764
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs04217
Necroptosis
nvs04380
Osteoclast differentiation
nvs04620
Toll-like receptor signaling pathway
nvs04621
NOD-like receptor signaling pathway
nvs04630
JAK-STAT signaling pathway
nvs04658
Th1 and Th2 cell differentiation
nvs04659
Th17 cell differentiation
nvs05145
Toxoplasmosis
nvs05160
Hepatitis C
nvs05161
Hepatitis B
nvs05162
Measles
nvs05164
Influenza A
nvs05165
Human papillomavirus infection
nvs05167
Kaposi sarcoma-associated herpesvirus infection
nvs05168
Herpes simplex virus 1 infection
nvs05169
Epstein-Barr virus infection
nvs05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
122909735 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
122909735 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
122909735 (TYK2)
04621 NOD-like receptor signaling pathway
122909735 (TYK2)
04658 Th1 and Th2 cell differentiation
122909735 (TYK2)
04659 Th17 cell differentiation
122909735 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
122909735 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
122909735 (TYK2)
05160 Hepatitis C
122909735 (TYK2)
05171 Coronavirus disease - COVID-19
122909735 (TYK2)
05164 Influenza A
122909735 (TYK2)
05162 Measles
122909735 (TYK2)
05168 Herpes simplex virus 1 infection
122909735 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
122909735 (TYK2)
05169 Epstein-Barr virus infection
122909735 (TYK2)
05165 Human papillomavirus infection
122909735 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
122909735 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nvs01001
]
122909735 (TYK2)
Enzymes [BR:
nvs01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
122909735 (TYK2)
Protein kinases [BR:
nvs01001
]
Non-receptor tyrosine kinases
JAK family [OT]
122909735 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
RA_2
Kinase-like
FERM_C_FAK1
RIO1
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
122909735
NCBI-ProteinID:
XP_044110161
LinkDB
All DBs
Position
6:216923655..216942319
Genome browser
AA seq
1195 aa
AA seq
DB search
MAYLFLAKPAVKSMSLCHWGATTRDSRPDGNGAQPMATRGGLKVLLHWAGPGGGDPWVTF
SEATLTAEEVCIHIAQKVGITPSCLNLFALFDAQAQVWLPPNHVLEIPRDLSLTLYFRMR
FYFRNWHGTNPQEPAVYRCGPPGPKSSSEQAEQGMQLLDPASFEYLFEQGKHEFVNDVAS
LWELSSEEEIHHFKNESLGMAFLHLCHLALCRGVPLEKVAKKISFKDCIPRSFQLQIRRH
NALTRLRLRNIFRRFVRAFQPGHVSQQVVMVKYLATLEQLAPRFGTERLPVCHLELLAQA
VGQPYYLRDAGQSPPEPGPELATGPPTHEVLVTGTGGIQWRPVRAEGPRGDGSSRNPCAG
PFGKRTKAPAAGDQPADRPQEELWTYFCDFQDITHVVLKECHVSVHCQDNKSLELTLPSR
AMALSLVSLVDGYFRLTADSSHYLCREVAPPRLVMSIQDGIHGPLLEPFVLAKLRPEDGL
YLIHWSTSHLNRLILTVAQREQAPGTQHVHLRKFPIELQAGVFTLEGWDRSFPSVRELRA
ALQGCCLRAGADCFALRRCCLPRPGEISNLIVMRGSRASAAPPNLSQLSFHRISQDDITQ
LSHLGQGTRTNVYEGILRVGGRDPKEGTADSEDPPTPSGDCGQELRVVLKVLDPSHHDIA
LAFYETASLMSQVSHVHLAFVHGICVHGSENIMVAEYVEHGPLDVWLRREKGHVPVAWKV
VVAQQLASALSYLEDKSLVHGNVCGRNILLARLGLTEGTSPFIKLSDPGVGLGALSREER
VERIPWTAPECLSGGANSLTTAADKWGFGATLLEICFDGEAPLQGRGPSEKECFYQKQHQ
LPQPSCPELATLTSQCLTYEPAQRPSFRTILRDLTQLQPQNLSDVLAVNPDSPASDPTVF
HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKTLKADCGPQLRTSWRREIDILR
TLYHKHIVKYKGCCEDAGEKSVPLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMA
YLHAQHYVHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC
LKECKFYYASDVWSFGVTMYELLTYCDSSQSPPSKFMELIGLTHGQMTVLRLTELLERGE
RLPRPERCPCEIYLLMKNCWQAEASFRPTFQNLIPILKTIQEKYQGQAASVFNVC
NT seq
3588 nt
NT seq
+upstream
nt +downstream
nt
atggcctatctctttctagccaagccagctgtcaaaagcatgtctctgtgccactggggt
gccaccaccagggacagcaggcctgatggcaatggagctcagcccatggccaccagggga
ggcctgaaggtccttctgcactgggctggccctggcggcggggacccctgggtcaccttc
agcgaggccacactgaccgcagaggaggtctgcatccacattgcacaaaaagtcggcatc
actccatcctgcctcaatctcttcgctctcttcgatgcccaggcccaggtctggctgccc
ccaaaccatgtcttggagatccccagagacctgagcctcacgctgtatttccgcatgagg
ttttatttccggaactggcatggcacaaacccccaggagccagctgtgtaccgctgtggg
cccccagggcccaagtcttcctctgaacaggcagagcagggcatgcaactactggacccg
gcctcctttgagtatctctttgagcagggcaagcatgagtttgtgaatgacgtagcatcg
ctgtgggagctgtccagcgaggaggagatccaccattttaagaatgagagtctgggcatg
gcctttctgcacctgtgccaccttgccttgtgccgtggcgtccccctggagaaggtggcc
aagaagatcagcttcaaggactgcatcccacgctccttccagctgcagatccggcggcac
aacgcgctgacccgactgcgcctgcggaacatcttccgcaggttcgtgcgggccttccag
ccgggccacgtctcacagcaggtcgtcatggtcaaatacctggccacgctcgagcagctg
gcaccccgcttcggcacggagcgcctgcccgtgtgccacctggaattactggcccaggcc
gtggggcagccctactacctccgggacgccgggcagtctcccccagagcctgggccggag
ttggccaccgggccacccactcacgaggtgctggtgacgggcacaggtggcatccagtgg
cggccggtgcgggcagagggtcccagaggcgatggcagcagcaggaatccctgtgctggc
ccatttgggaagagaaccaaggccccagcagcaggcgaccagccagcagacaggcctcag
gaagagctgtggacctacttctgtgacttccaggacatcacacatgtggtgctgaaggaa
tgccatgtcagcgtccactgtcaggacaacaagagcctggagctgaccctgccttcccgg
gccatggccctgtccttggtgtcactggtggacggctatttccgcctgaccgcagactcc
agccactacctgtgccgcgaggtggcgccaccacggctggtgatgagcatccaggacggg
atccacggacccctgctggagccatttgtgctggccaagctgcggcccgaggacggcctc
tacctcatccactggagcaccagccacctcaaccgcctcatcctcacggtggcgcagaga
gagcaggccccgggcacacagcacgtgcacctgcgcaaattccccattgagctgcaggcc
ggggtcttcacgctggagggctgggaccgctccttccccagcgtgcgggagctgcgagcc
gccctgcagggttgctgcctgcgggccggcgccgactgcttcgccctgcgccgctgttgc
ctgccacggcccggagagatctccaacctcatcgtcatgcgggggtctcgggccagcgcc
gctccgcccaacctcagccagctcagcttccaccggatcagccaggatgacatcacccag
ctgtcccacttgggccaaggcaccaggaccaacgtgtacgagggcatcttacgagtgggg
ggcagagaccccaaggagggcacggcagatagtgaggacccccccacgcccagtggggac
tgtgggcaagagctccgagtggtcctcaaggtgctggaccccagtcaccacgacatcgcc
ctggccttctacgagacagccagtctcatgagccaggtctcccacgtgcacctggccttt
gtacacggcatctgcgtgcacggctccgagaacatcatggtggcagagtacgtggagcac
gggcccctggacgtgtggctgcggcgggagaagggccatgtgcctgtggcctggaaggtg
gtggtggcccagcagctggccagcgccctcagctacctggaagacaagagcctggttcat
ggtaatgtgtgtggccggaacatcctgttggcacggctggggctgacggagggcaccagc
cccttcatcaagctgagtgaccccggtgtgggcctgggtgccctttccagggaggagcgg
gtggagcggatcccctggacagcccctgagtgcctctctggcggagccaacagtctgacc
actgcggccgataaatggggctttggtgccaccctcctggagatctgcttcgatggggag
gcccctctgcagggccgtggcccctccgagaaagagtgcttctaccagaagcagcaccag
cttcctcagccctcctgcccggagctggccacactcaccagccagtgcctgacctacgaa
ccagctcagcggccctccttccgcaccatcctgcgggacctcacccagctgcagccccag
aatctttctgacgtcttggctgtgaaccctgattcacctgcgtcagaccccaccgtgttc
cacaagcgctatttgaaaaagatccgagatctgggcgagggccatttcggcaaggtcagt
ctgtactgctacgaccccacgaacgacggcaccggtgagatggtggccgtgaagaccctc
aaggcggactgcggcccccagctccgcaccagctggcggcgggagatcgacatcctgcgc
acgctgtaccacaagcacattgtcaagtacaagggctgctgcgaggacgcaggagagaag
tcggtaccgctggtcatggagtatgtgcccctgggaagcctgcgggactacctgccccgg
cacagcgtggggctggcgcagctgctgctcttcgcccagcagatctgtgagggcatggcc
tacctccacgcacagcactatgtgcaccgagacctggcggcccgcaacgtgctgctggac
aacgacaggctggtcaaaatcggggactttggcctagccaaggctgtgcccgaaggccat
gagtactaccgcgtgcgcgaggatggggacagccccgtattctggtatgccccagagtgc
ctgaaggagtgtaagttctactatgcctctgatgtctggtcctttggggtcaccatgtac
gagctgctaacctactgtgactccagccagagccccccctcgaaattcatggagctcata
ggcctcacccatgggcagatgacggtgctgaggctcactgagctgctggaacgcggggag
aggctgccccggccggagagatgtccttgtgagatctatctcctcatgaagaactgctgg
caggcagaggcctcattccgccccaccttccagaacctcatacccattctcaagacgatc
caggagaaataccaaggccaggctgcctcagtgttcaatgtgtgctga
DBGET
integrated database retrieval system
