Neogale vison (American mink): 122912316
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Entry
122912316 CDS
T08764
Symbol
BACE1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
122912316 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
nvs01002
]
122912316 (BACE1)
Enzymes [BR:
nvs01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
122912316 (BACE1)
Peptidases and inhibitors [BR:
nvs01002
]
Aspartic peptidases
Family A1: pepsin family
122912316 (BACE1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
122912316
NCBI-ProteinID:
XP_044113849
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All DBs
Position
7:complement(107283410..107307460)
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AA seq
501 aa
AA seq
DB search
MAQALPWLLLWMGWGVLPARCSQPGIRLPLRSGLGAPPLGLRLPRETAEEPEEPSRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFITPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagcgctgccctggctcctgctgtggatgggctggggagtgctgcccgcccgc
tgctcccagccgggcatccggctgcccctgcgaagcgggctgggggcgccccccctgggg
ctgcggctgccccgggagaccgcggaggagccggaggagcccagccggaggggcagcttt
gtggagatggtggacaacctgaggggcaagtccggtcagggctactacgtggagatgacc
gtgggcagccccccgcagacgctcaacatcctcgtggacacaggcagcagtaactttgcg
gtgggggctgccccccaccctttcctgcatcgctactaccagaggcagctgtccagcacg
taccgggacctccggaagggcgtgtatgtgccctacacccagggcaagtgggagggggag
ctgggcaccgacctggtgagcatcccccacggccccaacgtcactgtgcgcgccaacatc
gctgccatcacagaatcagacaagttcttcatcaatggctccaactgggagggcatcctg
gggctggcctatgctgagatcgccaggccagatgactccctggagccgttctttgactcc
ctggtaaagcagacccacgttcccaacctcttctccctgcagctctgtggcgcaggcttc
ccactcaaccagtcggaagtgctagcctcagttggagggagcatgatcatcgggggtatc
gaccactcactatacacgggcagcctctggtacacacccatccggcgggagtggtactac
gaggtcatcatcgtgcgggtggagatcaacgggcaggacctgaaaatggactgcaaggag
tacaactacgacaagagcatcgtggatagcggcaccaccaaccttcgtttgcccaagaaa
gtgtttgaagctgccgtcaaatccatcaaggcagcctcctcgacggagaagttcccggac
gggttctggctgggggagcagctggtgtgctggcaggcaggcaccaccccttggaacatt
ttcccggtcatctccctctacctaatgggcgaggtcaccaatcagtccttccgcatcacc
atccttccacagcaatacctgcggccagtggaagacgtggccacgtcccaagatgactgc
tacaagttcgccatctcacagtcctccacgggcactgtgatgggagctgtgatcatggag
ggcttctacgtcgtctttgatcgggcccgaaagcgaatcggctttgctgtcagtgcttgt
catgtgcacgatgagttcaggacggcagcggtggaaggcccgtttatcaccccagacatg
gaagactgtggctacaacatcccacagacagacgagtcgaccctcatgaccatagcctac
gtcatggcggccatctgcgccctcttcatgctgccgctttgcctaatggtgtgccagtgg
cgctgcctccgctgcctgcgccaccaacacgatgactttgctgatgacatctccctgctg
aagtga
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