Neogale vison (American mink): 122915263 Help Entry 122915263         CDS       T08764                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism nvs  Neogale vison (American mink) Pathway nvs00230   Purine metabolism nvs01100   Metabolic pathways nvs01522   Endocrine resistance nvs04015   Rap1 signaling pathway nvs04020   Calcium signaling pathway nvs04022   cGMP-PKG signaling pathway nvs04024   cAMP signaling pathway nvs04062   Chemokine signaling pathway nvs04072   Phospholipase D signaling pathway nvs04081   Hormone signaling nvs04082   Neuroactive ligand signaling nvs04114   Oocyte meiosis nvs04211   Longevity regulating pathway nvs04213   Longevity regulating pathway - multiple species nvs04261   Adrenergic signaling in cardiomyocytes nvs04270   Vascular smooth muscle contraction nvs04371   Apelin signaling pathway nvs04540   Gap junction nvs04611   Platelet activation nvs04713   Circadian entrainment nvs04714   Thermogenesis nvs04723   Retrograde endocannabinoid signaling nvs04724   Glutamatergic synapse nvs04725   Cholinergic synapse nvs04727   GABAergic synapse nvs04740   Olfactory transduction nvs04750   Inflammatory mediator regulation of TRP channels nvs04911   Insulin secretion nvs04912   GnRH signaling pathway nvs04913   Ovarian steroidogenesis nvs04914   Progesterone-mediated oocyte maturation nvs04915   Estrogen signaling pathway nvs04916   Melanogenesis nvs04918   Thyroid hormone synthesis nvs04921   Oxytocin signaling pathway nvs04923   Regulation of lipolysis in adipocytes nvs04925   Aldosterone synthesis and secretion nvs04926   Relaxin signaling pathway nvs04927   Cortisol synthesis and secretion nvs04928   Parathyroid hormone synthesis, secretion and action nvs04934   Cushing syndrome nvs04935   Growth hormone synthesis, secretion and action nvs04962   Vasopressin-regulated water reabsorption nvs04970   Salivary secretion nvs04971   Gastric acid secretion nvs04972   Pancreatic secretion nvs04976   Bile secretion nvs05032   Morphine addiction nvs05163   Human cytomegalovirus infection nvs05166   Human T-cell leukemia virus 1 infection nvs05200   Pathways in cancer nvs05207   Chemical carcinogenesis - receptor activation nvs05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:nvs00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     122915263 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     122915263 (ADCY3)    04371 Apelin signaling pathway     122915263 (ADCY3)    04020 Calcium signaling pathway     122915263 (ADCY3)    04072 Phospholipase D signaling pathway     122915263 (ADCY3)    04024 cAMP signaling pathway     122915263 (ADCY3)    04022 cGMP-PKG signaling pathway     122915263 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     122915263 (ADCY3)    04081 Hormone signaling     122915263 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     122915263 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     122915263 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     122915263 (ADCY3)    04062 Chemokine signaling pathway     122915263 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     122915263 (ADCY3)    04923 Regulation of lipolysis in adipocytes     122915263 (ADCY3)    04912 GnRH signaling pathway     122915263 (ADCY3)    04913 Ovarian steroidogenesis     122915263 (ADCY3)    04915 Estrogen signaling pathway     122915263 (ADCY3)    04914 Progesterone-mediated oocyte maturation     122915263 (ADCY3)    04921 Oxytocin signaling pathway     122915263 (ADCY3)    04926 Relaxin signaling pathway     122915263 (ADCY3)    04935 Growth hormone synthesis, secretion and action     122915263 (ADCY3)    04918 Thyroid hormone synthesis     122915263 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     122915263 (ADCY3)    04916 Melanogenesis     122915263 (ADCY3)    04925 Aldosterone synthesis and secretion     122915263 (ADCY3)    04927 Cortisol synthesis and secretion     122915263 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     122915263 (ADCY3)    04270 Vascular smooth muscle contraction     122915263 (ADCY3)   09154 Digestive system    04970 Salivary secretion     122915263 (ADCY3)    04971 Gastric acid secretion     122915263 (ADCY3)    04972 Pancreatic secretion     122915263 (ADCY3)    04976 Bile secretion     122915263 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     122915263 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     122915263 (ADCY3)    04727 GABAergic synapse     122915263 (ADCY3)    04725 Cholinergic synapse     122915263 (ADCY3)    04723 Retrograde endocannabinoid signaling     122915263 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     122915263 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     122915263 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     122915263 (ADCY3)    04213 Longevity regulating pathway - multiple species     122915263 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     122915263 (ADCY3)    04714 Thermogenesis     122915263 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122915263 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     122915263 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     122915263 (ADCY3)    05163 Human cytomegalovirus infection     122915263 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     122915263 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     122915263 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     122915263 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     122915263 (ADCY3) Enzymes [BR:nvs01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      122915263 (ADCY3) SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA YbyB Peptidase_S49_N Motif Other DBs NCBI-GeneID:  122915263 NCBI-ProteinID:  XP_044117903 LinkDB All DBs Position 8:125025785..125105323 Genome browser AA seq 1145 aa AA seqDB search MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLLVAAMGLLLDLL LFVLCKKGLLPDRVTRKVVPYVLWLLITAQIFSYLGLNFSRAHAASDTVGWQAFFVFSFF ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLKGTHLLREILANVFLYLCAIVVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGEGGSRCE YLDEKGIETYLIIASKPEVKKTAAQHGLGGPALLNGAPASSKPGSPALIETKEPNGSVHT SGSTSEEPEDQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKKRNTFLLSMRFMDPDMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTN YMTFVVGEVLLLILTVCSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYYTGPNNSTTGLDVEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLVTGAVAVINIYAWRPIFDEYDRKRFQEHDFPVVALEKMQGLSTPGLNSTGRLPLVPSK YSMTVMIFIMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFASSNKEEKSDKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPAAFPNGSSVTLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggaaccagggcttctccgagcctgagtactcggctgagtactccgcagagtac tcggtcagcctgccctctgaccctgaccgcggggtgggccggacccacgaaatctcagtc cggaactcgggatcatgcctctgcctgcctcggttcatgcggctgaccttcgtgcccgag tccttggagaacttgtatcagacctacttcaaacggcagcgccacgagaccctgctggtg ctggtggtgttcgcggccctctttgactgctacgtggtagtgatgtgcgccgtggtcttc tccagcgacaagctggctcccctcctcgtggccgccatgggactgctgttggacctcctc ctcttcgtgctctgcaaaaaggggctgcttccagaccgggtcacccggaaagtggtgccc tatgtgctgtggctgctgatcaccgcccagattttctcctacctgggcctgaacttttcg agagcccatgcggccagcgacacagtgggctggcaggccttcttcgtattctccttcttc atcacgctgccgctcagcctcagccccatcgtcatcatctccgtggtctcctgtgtcgtg cacacactcgtcttgggggtcaccgtggcccagcagcagcaggacgggctgaagggcacg cacttgctgagggagatcctggccaacgtcttcctctacctgtgcgccatcgtcgtgggc atcatgtcctactacatggcggaccgcaagcaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccaacagcaggagaaccttatgctt tccatcctgcccaagcacgtggctgacgagatgctgaaggacatgaagaaggacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccggcacgagaacgtcagcatc ctctttgcggacatcgtgggcttcacccagctgtcctcggcctgcagcgcccaggagctg gtgaagctgctcaatgagctgtttgcccgcttcgacaagctggctgccaaataccaccag ctgcggattaagatcctgggcgactgctactactgcatctgcggcctgcccgactaccgg gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtac gtgcgggagaagacgaagacgggggtggacatgcgtgtgggggtgcacacgggtaccgtg ctggggggcgtcctgggccagaaacgctggcagtacgacgtgtggtcgaccgacgtcact gtggccaacaagatggaggccggtggcatccccgggcgcgtgcacatctcccagagcacc ctggactgcctgaagggcgagttcgacgtggagccaggcgaggggggcagccgctgtgag tacctggacgagaagggcatcgagacctacctcatcatcgcgtccaagccggaggtgaag aagacagccgcccagcatggcctcggcggcccggccctgctgaacggcgccccggcctcc tccaagcccgggtcccccgccctcattgagaccaaggagcccaacgggagtgtccacacc agtggctccacgtcggaggagcccgaggaccaggatgcccaggccgacaatccctcgttc cccaacccgcgccggaggctgcgccttcaggacctggcagaccgagtggtggatgcctcc gaggacgagcacgagctcaaccagctgctcaacgaggcgctgctggagcgagagtccgcc caggtagtgaagaagagaaacaccttcctcctttccatgcggttcatggaccccgatatg gaaacccgctactcggtggagaaggaaaagcagagcggggctgccttcagctgctcctgt gttgtcctgctctgtacggccctggtcgagatactcatcgacccctggctaatgaccaac tacatgacctttgtggttggggaggttctgctgctgatcctgacggtctgctcgctggct gccatctttccccgggcctttcctaagaagctcgttgccttctcgacctggattgaccgg acccgctgggccaggaacacctgggccatgttagccatcttcattctggtcatggcaaac gtcgtggacatgctcagctgtctccaatactacactgggcccaacaacagcaccacaggg ctggacgtggaggacggctgcgtggagaaccccaagtattacaactatgtcgccgtgctg tccctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacactcatg ctgctcgtcacgggggccgtggccgtcatcaacatctacgcctggcgccccatcttcgat gaatacgaccgcaagcgctttcaggaacacgactttcccgtggtcgccttagagaagatg cagggactttccacccctgggctcaacagcactggcaggctgcccctggtgccctctaag tactccatgactgtgatgatcttcatcatgatgctgagcttctactacttctcgcgtcac gtggaaaaactggcaaggacgctgttcttgtggaagatcgaggtccacgaccagaaagaa cgtgtctacgagatgcggcgctggaatgaggccttggtcaccaacatgctgcctgagcac gtggcccgccatttcctggggtccaagaagagagatgaggagctgtacagccagtcctac gacgagatcggagtcatgttcgcctccctgcccaacttcgccgacttctacacggaggag agcatcaacaacggcggcatcgagtgtctgcgcttcctcaacgagatcatctcagacttt gattctctgctggacaaccccaaattccgggtcatcaccaagatcaaaaccattggcagc acgtacatggcagcttcaggagtcaccccagatgtcaacaccaatggctttgccagctcc aacaaggaggagaagtcagacaaggagcgctggcagcacctggctgacctggcggacttc gctctggccatgaaggacacgctcacaaacatcaacaaccagtccttcaacaacttcatg ctgcgcatcggcatgaacaaaggaggggtcctggctggggtcattggagcccggaaacca cactatgacatctggggcaatacggtcaatgtggccagcaggatggagtccacgggggtc atgggcaacattcaggtggtggaagaaacacaagccatccttcgagagtacggcttccgc tttgtgaggcgagggcccatctttgtgaaggggaagggggagctgctaacttttttcctg aaggggcgtgataagccagctgccttccctaacggctcctcggtcaccctgccccaccag gtggtggataactcctga

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