Neogale vison (American mink): 122915783
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Entry
122915783 CDS
T08764
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs00140
Steroid hormone biosynthesis
nvs01100
Metabolic pathways
nvs05215
Prostate cancer
Module
nvs_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
122915783 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
122915783 (SRD5A2)
Enzymes [BR:
nvs01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
122915783 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
Motif
Other DBs
NCBI-GeneID:
122915783
NCBI-ProteinID:
XP_044118461
UniProt:
A0A8C7BW26
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Position
8:119168906..119216303
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AA seq
254 aa
AA seq
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MPLPCQQSPVLAGSATLAALGALVLYLAKPSGYGKYSESLLPTATRLPARAAWFLQELPS
FAVPAGFLARQPRSLFGQPATVLLGLFCAHYFHRTFVYSLLTRGRPFPVAFLVRGFIFCT
GNGLLQGYYLIYCAEYPAEWYTDGRFRLGVFLFILGMGVNIHSDYILRQLRKPGEVIYRI
PQGGLFKYVSGANFLGEITEWIGYALASWSLPALGFAFFSLCFLGLRAFHHHRFYLKMFE
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgccccttccctgccagcagagcccggtgctggcaggcagcgccactctggccgccctg
ggggcactggtcctgtacctggcgaagccctccggctacgggaagtactcggagagccta
ctgcccaccgctacccgcctgcccgcccgcgccgcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggttcctcgcccggcagccgcgctcgctcttcggccagcctgcg
acggtgctcctgggcctcttctgcgcacattacttccacaggacatttgtttactcattg
cttactagagggaggcctttcccagttgcattccttgtcagagggtttatcttctgcacg
ggaaatggacttctccaaggctactacctgatttactgtgctgaatacccagctgagtgg
tacacagacggacggtttcgcctgggtgtcttcttatttattttgggaatgggagtcaac
attcatagtgactatatattgcgccagctcaggaagcccggagaagtcatctataggatt
ccacaaggtggcttgtttaagtatgtttctggagccaatttcctcggtgagatcactgaa
tggatcggctatgccctggccagttggtccctcccagcgcttggatttgcatttttctca
ctttgtttcctggggcttcgagcttttcaccatcacaggttctacctcaagatgtttgag
gactatcctaaatctcggaaggccctcattccatttatcttctaa
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