Neogale vison (American mink): 122917144
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Entry
122917144 CDS
T08764
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
122917144 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
nvs03021
]
122917144 (SETX)
Enzymes [BR:
nvs01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
122917144 (SETX)
5.6.2.5 RNA 5'-3' helicase
122917144 (SETX)
Transcription machinery [BR:
nvs03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
122917144 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
nSTAND3
AAA_22
ResIII
SLFN-g3_helicase
NAT10_TcmA_helicase
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
122917144
NCBI-ProteinID:
XP_044120555
LinkDB
All DBs
Position
9:4044170..4130910
Genome browser
AA seq
2705 aa
AA seq
DB search
MPHTTKRFRRSKGGRVAGNAKARCRMSTCCWCTPGGISTVDFLQRYASRTHSGEFQTADE
DLCYCLECVAEYHRARDDLPFLHEVLWELETLRLINHFEKSMKAEIGDDDELYIVDNNGE
AQLFDFTGQDFENKLRVPLLEILKYPYLLLHERVNELCVEALCRMEQANCSFQVFDKHPG
IYLFLVHPNEMVRRWAILTARNLGKVDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSI
LEKGKLILLPSHMYDTSNYKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTME
RQSDDDSVDPFWPALHCFMVILDRLGSKVWGQRIDPIEAFQTIINNVSYNKEIQNIRNSS
VRTKLEPESYLDDMVTCSQIVYNYNPEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQS
DIGQDMRVHNSTFLWFIPFVQSLMDLKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDKVT
EFFLLILVSVIELHRHKKCLHLLWVSSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGT
AMISSLSLHSMPSNSVQLACVQLIRSLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQ
LTTQETHELQTCLKQIIKNIKVKVPQYNTFVDLSPACKSSPVSYSKEENEQIDRKSNKDL
SCLESSSPTFPKEPMKAETYKMQENVLIKASNTIEEDNEQNFIKDWKLEDHVPAESCIKK
SSKNLFTEKGQDHVKKSTGKQKSVKENCTSRNDPERGCDRGIIMSTRLLTSSSTESLEKA
STSTEDFSFKDDALGKTSKSKTKARKDEICAKLSHVIKKQHRKGTLVSNTGNLEENLAVS
NIDSFYSRKDSGGQKGDGFMHNLSLDPNGILDDKNGEQKSQNSLLLKKKPLKSEEVDIFS
SHENSYQIQECHIDNKDLVSFTEVTNTFVKKTPFKDPVTVLESRDKESSKNTSQLSSHLR
EQALGLSPQSDTLTDSQVDRDLHKLSLIAQASVIKFPSDSTQKSSSQLQRRVKDDRRCFL
ADQNNTGEACRGQIIIISDSDDDDDDEILGFERHIKQDKIGIKKECPEQHTSIANVNVEK
KLMKEEETKSLLQFEESDSQFFEFESPCEVFSVWQDQEPDKNSVQENEKNSCSADIADIT
NDWGYETDYVSEEVIKKVAEGIEKHTEPQSSISVGEIRETEVKKRKRKRFEKPMAEDHPR
PSPSDRNEDQPDILNERSVTENDFKSVDLRTSPSSSVQRDKDTTVALKKSSPKLRSYSKP
IRRVPLSKTPKKTHSDTKKGQNKSSNYISCRTTPAIVPPKKLRQCPEPTSAVEKLGLKKA
PRRAFELSQRSLEYLVQLRDHGKTVGVVDTRKKTKLISPQTLSVKNNKKLLTSQDLQLRR
QMRSKSQKSRQGLSDYESKDTTRAGPCAAQNSDILVPESDGSDYSSKGGTEVVANTTGKQ
SIKCASSEPEPMKTKYVSQVTDDTCLLSPCASVVLNGRIPTKEINVSASADPLGGSDPIV
HRLELATLKDGELDSNSDTEDENIFLTQHNPEDMDLCSQMENGNEKLIEVIRGKDKAQVE
EDSVSRPHLESWSSTKCKYKDCVETPKNQGEYCAKHSEAKAADEDVFRKPGLPLSASKPS
RPSTAKIFSSSSTSRIANLSKSLESTPALPPALKNKSSGAQAVLKVPQPASVLSPKPVGE
VKSLCNVLHPQTPNNSSRQGYKLTFGESKSFSASTPVNILLSSQSISDTFVKEVLKWKYE
MFVNFDQCGPPASLCQSISRPVPIRFQDCGDYFDVFFPLMILNTFETVAQEWISSTNKEK
FYQLHLRKFPADYKKYWEFVVHLEECELAKQLHPKENDLVFLIPERQNGENKDTEREHME
DLRDYHCAYVHKFRRTSVMRNGKSECSLSIQTQDNLPVNLNELVKCIVISSLVTTQRKLK
AMSLLSGRNQLARAVLNPNPMDFCTKDLLTTTSERIITYLRDFNEDQKKAIETAYAMVKH
SPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNA
AVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKK
DLPSHVQEMHRRKEFLDRQLDELSRQRALCRGGREMQRQELDEEIGKVSKERQELASKIK
EVQGRPQKTQSIIILESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVET
LTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFYKLLEDSVEHSVVGRLPV
LQLTVQYRMHPDICLFPSSYVYNRSLKTSRQTETSRCSSDWPFQPYLVFDVGDGSERRDN
DSYVNVQEIKLVMEIIKLIKDKRRDVTFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEV
DTVDGFQGRQKDCVIVTCVRANTVQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMEN
QHWNHLIQDAQKRGAIIKTCDRNYRHDAAKILKLKPVLQRSATHPPAVAPEASRPPGGLP
SSRLDSELAKTSFTSLYHTPSDSRESAGTVTAKDPERPLIQDRLRDPRLLRRLGLDPETR
GPCLRDPRPLSPQHPGATPPSGEPGFPGSPQDLGGAQQSTARGAALNNHKPQAHGEPPAA
GTEVSASKRRCDWEEGLGSRRETRALSAGDQEKGSPESHHSKSSPGWDKRGLEKEDGSSK
RRRLL
NT seq
8118 nt
NT seq
+upstream
nt +downstream
nt
atgccacataccacgaagcgttttcggaggagcaagggagggagagtggcaggaaatgcc
aaagccaggtgcagaatgagcacatgttgttggtgtacgccaggtggcatttccaccgtt
gacttcctgcagcgctatgcgtccaggacccactctggcgagtttcaaacagctgatgaa
gacctctgctattgcttagagtgtgtagccgaataccacagagcaagggacgacttacca
ttcctgcatgaggttttatgggaattagaaaccttacgtctcataaatcactttgaaaaa
tccatgaaggcagaaattggagatgatgatgaattgtatatagtagacaacaatggagag
gcacagctgtttgactttactggccaagactttgaaaataagcttcgagttcctcttctt
gaaatactgaaatatccttatctgcttttacatgagcgtgttaatgaattatgtgttgaa
gcactttgtcggatggaacaagctaattgctcctttcaggtttttgacaaacatccgggc
atctatttgtttttggtccatcccaatgaaatggttcggcgttgggctatcctgaccgca
agaaatttgggaaaagtggacagagatgattattatgacttgcaggaggttttgacttgt
ctttttaaagtcattgagttggggcttttggaaagtccagacatttatacttcttctatc
ctcgagaagggtaaactgattcttctgccctcacacatgtatgataccagcaactacaaa
aactattggttaggtatttgcatgttgctgaccattctggaggagcaggccatggactca
ctgttgctgggctcagacaaacagaatgatttcatgcagtcaatacttcacaccatggag
aggcaatcagatgatgatagtgtggatcctttctggccagcattacactgtttcatggtg
attctggatcgcctcggatccaaggtttggggtcaacgtattgatcctattgaggcattt
caaaccattatcaacaatgtgagctacaataaagagatccagaatatacggaacagctct
gtgaggaccaagttagaaccggagtcatatttggatgatatggtgacttgcagccagatt
gtatacaattataatcctgaaaagaccaaaaaggattcggggtggagatcagccatttgc
ccggattattgtcctaacatgtatgaagagatggaaacattagccagtgtgcttcagtca
gatattggtcaagacatgcgtgttcataacagcacgtttctgtggttcatcccttttgtt
cagtccctcatggatcttaaggatttgggtgtggcttatatagtggaggttattcatcat
ctgcactccgaagtcaaagatgtcctcaaccaaacagatgctgtgtgtgacaaagttact
gaattttttcttctaattttggtgtctgtgattgagctgcatagacataaaaaatgtctg
catctgctgtgggttagttcccagcaatgggtagaagctgttgtaaaatgtgccaagctt
cctaccactgcatttgcacggagttccgagaagtcatctggaaattgctccaaaggaaca
gcaatgatatcatctctgtcattgcattcaatgccatcgaattctgtgcagctggcttgt
gtgcagctgattagaagtctccttaaagaaggttatcagcttgggcagcaaactctatgt
aagcgattctgggataagctcaacttatttctgcgtggaaatttatcgctaggttggcag
ttgactactcaggaaacccatgaattacaaacttgtttaaagcaaattattaaaaacata
aaagtcaaagtacctcaatataacacttttgtggatctgagtcctgcatgtaaaagctct
cctgtgtcttatagtaaagaagaaaatgaacaaatagataggaagtctaataaagacctg
tcctgtctagaaagctccagcccaacatttcctaaagaaccaatgaaagcggagacctat
aagatgcaagagaatgtattgatcaaagcaagtaacactatagaagaggataatgagcaa
aattttataaaagactggaaactagaagatcatgtcccagccgagtcatgcataaagaag
agtagtaaaaaccttttcactgaaaaaggtcaagatcacgttaaaaaaagtacagggaag
cagaagtctgtgaaagagaattgtacttcaaggaatgatccagaaaggggatgtgacaga
ggaataatcatgtcaacacgtttgttaaccagctctagcactgaatctctggagaaggca
tccacatcaactgaggatttctctttcaaggatgatgctcttggcaaaacctcaaaatca
aaaactaaggcacgtaaagatgaaatctgtgctaagttatcacatgtaataaagaagcaa
cacaggaaaggaactttggtcagtaatactggtaatttagaggaaaacctagctgtgtct
aacattgacagtttctattcaaggaaagattcaggaggtcagaaaggggacggctttatg
cacaatctctctttagatcctaatggcattctggatgataaaaatggggaacaaaaatct
caaaacagtttattgctgaaaaagaaaccactgaagagtgaagaagtagatattttctct
tcccatgaaaacagctatcaaatacaggaatgtcacattgataataaagatttggtctca
tttacggaagtgaccaacacttttgtgaagaaaactcccttcaaagatcctgtgactgtt
cttgaatcaagagataaggaaagtagcaagaacactagtcagttgtcttctcacttgaga
gaacaggctcttggcctaagtcctcagtctgacaccttaacagattctcaggtagacaga
gacctccacaagttatctttaatagctcaggccagtgttattaagttcccatcagattca
actcaaaaaagctcatcccagctacaaagaagagtgaaagatgacagaaggtgtttcctg
gctgaccagaataatactggggaagcctgccgcggccagattattattatttcagattct
gatgatgatgacgatgatgaaattctgggttttgagagacatattaagcaagataaaata
ggcatcaagaaagaatgtccggagcagcatacttcaatagctaatgtgaatgtggaaaag
aagctaatgaaggaagaggagacaaagtcccttttgcagtttgaggaatcggattctcag
ttttttgagtttgaaagtccatgtgaagtgttttctgtttggcaagatcaggaaccagac
aagaattcagttcaagagaatgagaaaaattcttgttcagctgacatagctgatatcaca
aatgattggggttatgaaacagattatgtatctgaagaggttattaagaaagtagcagaa
ggcattgaaaaacacacagaaccgcagagcagtatttctgttggggaaatacgtgaaact
gaagtaaaaaaacgtaagcgaaaacgatttgaaaaacctatggctgaagatcatccaaga
ccttcaccttctgatagaaatgaggaccagcctgatattcttaatgagagaagtgtgact
gaaaatgattttaaaagtgtggacctaaggacaagtcctagttcaagtgttcagagagac
aaagacactacagttgcactaaagaagtcttctccgaagcttcgttcttattccaaaccc
attaggagagtcccactttctaaaactcctaagaaaacgcattcagataccaagaaaggg
cagaataaaagttcaaattacatcagttgtaggacaactcctgctatagttccaccaaag
aagttgcgccagtgccctgagccaacttcagcggttgagaaacttggtctaaagaaggct
cctcgtagggcatttgagttgtctcagcgatctctagagtatttagttcagttacgcgac
catggcaaaactgttggagtggttgatactagaaaaaagactaagttaatttcccctcag
actctctctgtgaaaaataataagaaactgctgacaagtcaagatcttcagttgcgaagg
cagatgagatccaaatcacaaaaaagtagacaaggactttcggattatgaaagtaaagat
actacaagagcagggccgtgtgcagcacagaattctgacatacttgtcccagaatcagat
ggttcagattatagttctaaaggaggaactgaggtggttgctaacaccactgggaaacag
tccataaaatgtgcatcttcagaaccagaacccatgaaaacaaaatatgtctctcaagtg
acagatgatacttgcctcttgagcccgtgtgcttctgttgtgttaaatggaagaatacca
acaaaggaaataaatgtctctgcttcagccgaccccttaggtggaagtgacccaatagta
catcgtttagagttggcaactttgaaagacggagagctggactcgaacagtgatacagaa
gatgagaatatatttctgacacagcacaatcctgaagatatggatttgtgttcacagatg
gagaacggtaatgagaaactcattgaagtaattcgtggcaaagataaagcacaggtggaa
gaagattctgtaagtcggcctcacttggaatcttggagtagcacaaaatgtaagtacaaa
gattgtgttgaaacaccgaaaaaccagggtgaatactgcgcaaaacactctgaagccaaa
gcagccgatgaagatgtatttcgtaaacctggcttgcctctttctgcatctaagccttca
agaccttccactgctaagatttttagctcaagtagtacttcacgaattgctaatctttcc
aagtctttggaaagtacccctgcccttccaccagctctaaaaaataagtcaagtggggca
caggctgttttgaaagtcccacagccagcctctgtgttgtctccaaagccggtgggtgaa
gtgaagagtttgtgcaatgttcttcatcctcagactccaaataattccagcaggcaaggt
tacaaactgacgtttggtgaaagcaaatccttctcagcttccactccagtcaacattctc
ttgtcatcacagtccatctctgacacctttgtcaaagaggtcttaaaatggaaatatgaa
atgtttgtgaactttgatcagtgcgggcccccagcaagcctttgtcagtccatctcaaga
cctgtgcctatcagatttcaagattgtggtgactattttgatgtttttttccctttgatg
atactgaatacttttgaaacagtggcacaggagtggatcagctctactaacaaagagaaa
ttctatcagttgcatttacgaaaatttcctgctgattataaaaaatactgggagtttgtg
gttcatcttgaggaatgtgaactcgctaaacaacttcatccaaaggaaaatgatttggtg
tttttgattcccgaaagacaaaacggagagaataaagatacagagagagagcacatggaa
gatctccgtgattaccactgcgcgtatgttcataagtttcgccgcacttccgtcatgcgc
aacgggaaatctgagtgttccctttccatccagactcaagataatttgccagtcaattta
aatgagctcgtgaaatgcattgtaatcagttctctggtaactacacaaaggaagttgaaa
gccatgtctttgttgagtggacggaaccaactggccagagctgttctgaatccaaaccct
atggacttctgtacgaaagatttactaactacaacatctgagagaattatcacctactta
agagatttcaacgaagaccagaagaaagcgatagaaaccgcatatgccatggtcaagcac
tccccgtctgttgccaagatctgtctgatacatggaccacctggaacaggaaaatcaaaa
actattgttggcctcctgtaccgcctcctgacagagaaccagaggaagggccattcagat
gaaaactccaatgccaaaatcaaacaaaaccgtgtccttgtgtgtgcgccttccaacgcg
gctgttgatgagcttatgaaaaaaatcatcctcgaatttaaagaaaaatgtaaagacaag
aagaatcctttgggaaactgtggagatataaatttagtacgtctcggtccagaaaagtct
attaataatgaggtcctaaaattcagtttggatagccaagttaaccacagaatgaaaaaa
gacttaccgtctcatgttcaggaaatgcatagaagaaaggaatttctagatcgtcaacta
gatgaactttcccgccagcgtgctttatgtcgaggtggaagggaaatgcagaggcaagaa
ttagatgaagaaattggaaaagtttcaaaagagaggcaagaactagcttctaaaattaaa
gaggttcaaggacgcccacaaaaaacacagagcatcatcatcttggagtcccatgtcatc
tgctgcacactgagcacaagtggtggcttactgcttgagtctgcttttcgtgggcaaggg
ggtgtccccttcagttgtgtcattgtggatgaggccgggcagtcttgtgaggttgagact
ctcactccactcatccatcgttgtaacaagctcatcctcgtgggagatccgaaacagctc
cctcccacggtaatttctatgaaagctcaggagtacggctatgaccagtccatgatggca
cgcttctacaagctgctggaagacagcgtggagcacagcgtggtcggccggctgccggtc
ctgcagctcaccgttcagtaccggatgcacccggacatctgtctcttcccttccagctat
gtttacaacagaagcttgaagacgagtagacagactgaaaccagtcgctgttcatcagac
tggccatttcaaccttacctggtgttcgatgttggagacggttcagaaagacgggacaat
gactcatatgtaaatgttcaagaaataaaactggtaatggaaataattaaacttattaaa
gacaaaagaagggatgttactttccggaacattggcataataacccattacaaggctcag
aagacgatgattcagaaggatttggacaaagaatttgatagaaaagggccagcagaagta
gataccgtggatgggttccagggtcggcagaaggattgtgtcattgtcacgtgcgtccga
gcaaatactgtgcagggctcaattgggtttctggcgagtttgcagagactgaacgtcacc
atcacccgagccaagtacagcctcttcatccttggacacttaaggaccctcatggagaac
cagcactggaaccacctgatccaggacgcccagaagcgcggcgccatcatcaagacgtgt
gacaggaactacaggcacgacgcggccaagatcctgaagctgaagccggtgctgcagagg
agcgcgacacacccccccgccgtcgccccggaggcgtccagacccccgggcggcttgccc
agcagcaggctggacagcgagctcgccaagacgtccttcacgtccctctaccacacgccc
tcggactccagggaatctgctggtaccgtcacggcgaaggaccctgaaaggccccttatc
caggaccggcttcgggacccaagactgcttaggaggctgggcctggaccctgaaaccaga
gggccgtgcctcagggatccgcggcctttgagcccccagcatcccggggcgacaccgccc
tcgggggagccaggcttccccgggagtccccaggatctgggaggcgctcagcagtccact
gccaggggggccgctctgaacaaccacaaacctcaggcgcacggtgagcctccagctgct
gggaccgaggtctccgcgagtaaaagaagatgtgactgggaagaagggctcggctccagg
agagagacgcgcgctctcagtgcgggggaccaagagaaggggagcccggagagccaccac
tcgaagagcagccctggctgggacaagaggggactggagaaggaggacggcagctcaaag
agaagaaggctcttgtag
DBGET
integrated database retrieval system
