Neogale vison (American mink): 122917225
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Entry
122917225 CDS
T08764
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs00790
Folate biosynthesis
nvs01100
Metabolic pathways
nvs01240
Biosynthesis of cofactors
nvs01523
Antifolate resistance
nvs04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
122917225 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
122917225 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
122917225 (FPGS)
Enzymes [BR:
nvs01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
122917225 (FPGS)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
122917225
NCBI-ProteinID:
XP_044120771
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Position
9:complement(7547366..7566639)
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AA seq
589 aa
AA seq
DB search
MSQARCHLRAALFLAAVSSRGATTGVTARRGLSARPAPQEPGMEYQDAVRTLNTLQTNAG
YLEQVKRQRGDPQTQLDTMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGRPVSPELFTKHFWHLYHRLEETKDSSSCVSMPAYFR
FLTLMAFHIFLQEKVDLAVMEVGIGGAYDCTNIIRKPVVCGISSLGIDHTSLLGDTVEAI
AWQKGGIFKRGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLARCWLQQKGHQGLGELKMSRPSVLRQMPLAPVFQPTSHMRHGLRDTE
WLGRTQTLQRGPLTWYLDGAHTVSSVQACVRWFRQALHRSQRPNRGREVRVLLFNSTGNR
DSEALLKLLQPCQFDYAVFCPNLTEVSSASNADQQNFMVTLDQVLLRCLAHQQHWSHLDE
EPASPDLWSSTSPEPGDEHTSLLLASRPHHPHSTGSLVFSCISHALQWISQGRDPVFQPP
SPPPSLLAHPVAGSGAGVLREAAAIHVLVTGSLHLVGGVLKLLDPSLSQ
NT seq
1770 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcaggcacgctgccacctgcgcgccgctctcttcctggcagcagtttcttcgcgc
ggtgccacgaccggggtcacggcgcggcgagggttgagcgcgcggcccgcgccgcaggag
cccggcatggagtatcaggatgctgtgcgcacactgaacaccctgcagaccaatgctggc
tacctggagcaggtgaagcgccagcggggtgaccctcagacgcagctggacacgatgaag
ctgtacttggcccggagtgggctgcaggtggaagacttggaccagctgaacatcattcac
gtcactgggaccaaggggaagggttccacttgtgccttcactgaacgtattctccgcagc
tatggcctgaagacaggattctttagctctccccacctggtgcaggtgcgggagcggatc
cgcatcaacgggcggcccgtaagccccgagctcttcaccaagcacttctggcacctctac
caccggctggaggagaccaaggacagcagcagctgtgtctccatgcccgcctacttccgc
ttcctcacactcatggccttccacatcttcctccaagagaaggtggacctggcggtgatg
gaagtgggcattggtggcgcttacgactgtaccaacatcattcggaagcctgttgtgtgt
ggcatctcctctcttggcattgaccacaccagccttctgggggacacagtggaggcgatc
gcatggcagaaagggggcatcttcaagcgtggcgtccctgccttcacggtgctccagcct
gacggtcccctggcagtgctgcgggaccgtgcccagcagatctcctgtcctctctacctg
tgcccaccactcgaagccctggaggaaggcgggccgccgctgaccctgggcctggaggga
gagcaccagcggtccaacgccgccttggccttgcagctggctcgctgctggctgcagcag
aagggccaccagggccttggagagctgaagatgtctcgacccagcgtcttgcggcagatg
cccctggcacccgtgttccagcccacatcccacatgcgacatgggcttcgggacaccgag
tggctgggccggacgcagacactgcagcgcgggcccctcacctggtacctggacggcgcg
cacaccgtgagcagcgtgcaggcctgcgtgcgctggttccgccaggcgctgcaccgcagc
cagaggccgaaccgcggccgtgaggtgcgcgtcttgcttttcaactccactgggaaccgg
gactcggaggccctgctgaagctgctgcagccctgtcagtttgactatgccgttttctgc
cctaacctgacggaggtgtcatctgctagcaacgcagaccagcagaacttcatggtgacc
ctggaccaggtgttgctccgctgccttgcacatcaacagcactggagccacctggatgag
gagccggccagcccagatctctggagctccaccagcccggagcctggtgatgagcacacg
tccttgctgctggcttctcgcccacaccacccccacagcaccggctcccttgtcttcagc
tgcatctcccatgccctgcagtggatcagccaaggccgggaccctgtctttcagccaccc
agtccccccccaagcctccttgctcaccctgtggctggcagtggggcgggcgtgctccgt
gaggctgccgccatccatgtactagtcacaggcagcctgcacctcgtgggtggcgtcctg
aaactgctggacccttccctgtcccagtag
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