KEGG   Neogale vison (American mink): 122917804
Entry
122917804         CDS       T08764                                 
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
nvs  Neogale vison (American mink)
Pathway
nvs04064  NF-kappa B signaling pathway
nvs04072  Phospholipase D signaling pathway
nvs04151  PI3K-Akt signaling pathway
nvs04380  Osteoclast differentiation
nvs04611  Platelet activation
nvs04613  Neutrophil extracellular trap formation
nvs04625  C-type lectin receptor signaling pathway
nvs04650  Natural killer cell mediated cytotoxicity
nvs04662  B cell receptor signaling pathway
nvs04664  Fc epsilon RI signaling pathway
nvs04666  Fc gamma R-mediated phagocytosis
nvs05152  Tuberculosis
nvs05167  Kaposi sarcoma-associated herpesvirus infection
nvs05168  Herpes simplex virus 1 infection
nvs05169  Epstein-Barr virus infection
nvs05171  Coronavirus disease - COVID-19
nvs05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:nvs00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    122917804 (SYK)
   04072 Phospholipase D signaling pathway
    122917804 (SYK)
   04151 PI3K-Akt signaling pathway
    122917804 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    122917804 (SYK)
   04613 Neutrophil extracellular trap formation
    122917804 (SYK)
   04625 C-type lectin receptor signaling pathway
    122917804 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    122917804 (SYK)
   04662 B cell receptor signaling pathway
    122917804 (SYK)
   04664 Fc epsilon RI signaling pathway
    122917804 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    122917804 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    122917804 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    122917804 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    122917804 (SYK)
   05168 Herpes simplex virus 1 infection
    122917804 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122917804 (SYK)
   05169 Epstein-Barr virus infection
    122917804 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    122917804 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nvs01001]
    122917804 (SYK)
Enzymes [BR:nvs01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     122917804 (SYK)
Protein kinases [BR:nvs01001]
 Non-receptor tyrosine kinases
  SYK family
   122917804 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 Kdo DUF7063 ABC1 RIO1
Other DBs
NCBI-GeneID: 122917804
NCBI-ProteinID: XP_044122035
UniProt: A0A8C7BN78
LinkDB
Position
9:100743644..100782231
AA seq 635 aa
MAGSAADGANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKA
HHYTIEREMSGTYAIAGGRTHGSPAELCLYHSQESDGLVCLLTKPFHRPPGVQPKTGPFE
DLKESLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRVESEQI
VMIGSKTNGKFLIRDRNDNGSYALCVLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLV
EHYSYKPDGLLRVLTVPCQKIGGQTGNINFGARAPLPGAHPATWSAGGIISRIKSYSFPK
PGHRKASSSAGSRPESSVTFNPYEPDRGPWATDRDAQREAMPMDTEVYESPYADPEEIRP
KEVYLDRKLLTLEDSELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
GMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPAGCPRE
MYELMKLCWTYEVEKRPSFENVELRLRNYYYDVVN
NT seq 1908 nt   +upstreamnt  +downstreamnt
atggcggggagcgcggccgacggcgccaaccacctgcccttcttcttcggcaacatcacg
cgggaggaggcggaggactacctggtccagggcggcatgagcgacgggctgtacctgctg
cggcagagccggaactacctgggcggcttcgcgctgtcggtggcgcacggcaggaaggcg
caccactacaccatcgagcgcgagatgagcggcacctacgccatcgcgggcggcaggacg
cacggcagcccggccgagctctgcctctaccactcgcaggagtccgacggcctggtctgc
ctcctcaccaagcccttccaccggccgcccggggtgcagcccaagaccggccccttcgag
gacctgaaggagagcctcatccgcgagtacgtgaagcagacctggaacctgcagggccag
gccctggagcaggccatcatcagccagaagccacagctggagaagctgatcgccaccacg
gcccacgagaagatgccttggttccacgggaaaatctcaagggtcgaatctgagcagatc
gtcatgataggatccaagacaaacggaaagtttttgatcagggacaggaatgacaacggg
tcgtacgccctgtgcgtgctgcacgaggggaaagtgctgcactaccggatcgacaaggac
aagacgggcaagctctccatccccgacgggaagaagttcgacacactctggcagctggtg
gagcattactcttacaaacccgatggactgctgagagttctcacggttccgtgccagaag
atcggagggcagacaggaaacatcaacttcggagcccgcgcgcccctcccgggagcccat
cctgccacgtggtcggcgggtggaataatttccagaatcaaatcgtactccttccccaag
cctggccacagaaaggcctcctcgtccgcagggagccggcccgagagctccgtgaccttc
aatccttacgagccagaccgggggccttgggccacggacagagatgcccagagagaagcc
atgcccatggacaccgaggtgtacgagagcccctacgcggaccccgaggagatccggccc
aaggaggtctacctggaccgcaagctgctgaccctggaggacagtgagctgggctccggc
aacttcgggaccgtgaagaagggctactaccaaatgaaaaaagtcgtgaagacggtggct
gtgaagattctgaagaacgaggctaacgatcccgcccttaaagacgagttgttagcagaa
gcgaacgtcatgcagcagctggataacccgtacatcgtgcgcatgatcgggatatgtgag
gccgagtcctggatgctggtcatggagatggccgagctcggtccgctcaacaaatactta
cagcagaacaggcacgtcaaggacaagaacatcatagaactggttcaccaggtttctatg
gggatgaagtacttggaggaatgcaacttcgtgcacagggatctggcggcaagaaacgta
ctgctcgtgacgcaacattacgccaagatcagtgatttcggactttccaaagcactccgc
gctgacgaaaactactataaggcgcagacgcacggcaagtggccggtgaagtggtacgct
cccgagtgcatcaactactacaagttctccagcaagagcgacgtctggagcttcggcgtg
ttgatgtgggaggcgttctcctacgggcagaagccctaccggggcatgaaaggaagtgaa
gtttcggctatgctggagaaaggggagaggatggggtgccccgcggggtgcccgagggag
atgtacgagctgatgaagctgtgctggacgtatgaggtggagaagaggccgagtttcgaa
aacgtggagctgcggctgcgcaattattactacgacgtggtgaactaa

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