Neisseria wadsworthii: H3L96_07550
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Entry
H3L96_07550 CDS
T07067
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
nwd
Neisseria wadsworthii
Pathway
nwd00790
Folate biosynthesis
nwd01100
Metabolic pathways
nwd01240
Biosynthesis of cofactors
Module
nwd_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
nwd00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
H3L96_07550 (folC)
Enzymes [BR:
nwd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
H3L96_07550 (folC)
6.3.2.17 tetrahydrofolate synthase
H3L96_07550 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
SIS_2
Motif
Other DBs
NCBI-ProteinID:
QMT34928
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Position
1590036..1591325
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AA seq
429 aa
AA seq
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MKKNLNDWLSHLETAHSAGLIDMGLSRAGEVKNTMRLNPQCPVIVVAGTNGKGSVCAFLS
QIYKEAGFKTGTLTSPHLLKFNERICVNTQPVSDEEIVAAFERIEAARGDISLTYFEFNT
LAAVDIFMWNQVDVMILEVGLGGRLDAVNIFDADVSVVTSIDLDHQSFLGNTIEQVAYEK
AGVFRSGKPAICGQNPPPESLRKHAGSIGADLLLIGEDFSYTRLENQQWSYRFHSQPNPQ
FSDRHTRNRNALPIPALRGAYQIHNAACALTVIECLNHQLPIDIGAIKRGLLMVHNPGRF
QVLPGRPLTVLDVGHNPHAARALRQGLMALPFAQNRTAVLSMLNDKDIDSVLEILKDQFD
EWHIAPLHLPRGMTSEQLAEKLAAHDISNVKQFENIAKAYDAAFAAASENDRIVVFGSFH
TVAEVMGTL
NT seq
1290 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaaaaatctgaacgactggctctcccatttagaaaccgcccacagcgcgggtttg
attgatatgggcctatcccgtgcgggcgaagtgaaaaataccatgcgcctgaacccgcaa
tgcccggtaatcgttgtggcgggcaccaacggcaaaggttcggtgtgtgcatttttatcg
cagatatataaagaagccggcttcaaaaccggcacactgaccagcccgcatctgttgaaa
ttcaacgagcgcatttgtgtcaacacacagcctgtgtcagatgaagaaattgtggccgcg
tttgagcgtattgaagccgcgcgtggcgatatttccctcacttattttgaattcaacacg
ctggccgccgtggatattttcatgtggaatcaagtggatgtgatgatattggaagtcggg
ctgggcggccgtttggatgccgtgaacatatttgacgccgacgtgtccgtggtaaccagc
attgatttagaccaccaatctttccttggcaacaccatagagcaagttgcttatgaaaaa
gccggtgtgttccgcagcggcaaacccgccatctgcggtcagaacccgccacccgaatcg
cttagaaaacatgctggaagcataggtgcggatttattgttgatcggagaagatttcagc
tataccaggctggaaaaccagcaatggtcataccgttttcactcacagcctaatccgcag
ttttcagacaggcatacgcgcaaccgcaatgccttgccgattcccgccttgcgcggtgca
tatcaaatccataacgcagcctgtgcgctgaccgttatcgagtgcctcaaccatcaattg
ccgatagacataggcgccatcaaacgcggtttgttgatggtacataaccccggccgtttc
caagttttacccggcaggccgctgaccgttttggatgtgggccataacccgcatgcagcc
cgtgcgctgcgtcaagggctgatggccttgccgtttgctcaaaaccgcacggctgtgctc
agcatgttgaacgacaaggacattgattcggttttggaaattttgaaagaccagtttgac
gaatggcatatcgcgccgctgcatctgccgcgcggcatgacttccgagcagcttgccgaa
aaactggctgctcacgatataagcaatgtaaaacagtttgaaaatatagcaaaagcttat
gatgcggcttttgcggcggcttcggaaaatgatagaattgtcgtgttcggctccttccat
acggttgccgaagttatgggaacactataa
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