Neisseria weaveri: SAMEA3174300_0404
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Entry
SAMEA3174300_0404 CDS
T04355
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
nwe
Neisseria weaveri
Pathway
nwe00790
Folate biosynthesis
nwe01100
Metabolic pathways
nwe01240
Biosynthesis of cofactors
Module
nwe_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
nwe00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SAMEA3174300_0404 (folC)
Enzymes [BR:
nwe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SAMEA3174300_0404 (folC)
6.3.2.17 tetrahydrofolate synthase
SAMEA3174300_0404 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
SAY50529
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Position
1:449955..451247
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AA seq
430 aa
AA seq
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MKTLDDWLSHLETAHSAGLIDMGLSRVGEVKTRMGLVPQCPVIVVAGTNGKGSVCAFLSH
IYSQAGYKTGTLTSPHLLRFNERIAVNTEPVSDEAITASFERIEAARGDISLTYFEFNTL
AAVDVFMREKVDVMILEVGLGGRLDAVNIFDADCAVVTSVDLDHQAFLGDNIEAVAYEKA
GVFRPFKPAVCGQNPPPESLKKHAEDIQADLLLIKDDFSLTKLEQQQWSFHFHPQEAVSH
FAEGFKRNRNALPIPALRGSYQLGNAACALAVLECMNAVLPVDIGAIKRGLLLVNNPGRF
QVLPGRPLVILDVGHNPHAARALRQSLIALPFAEKRIAVFSILADKDIDGVLETVKDQFD
EWYIAPLHLPRGMSVEALKNKLAEHDIADNVKAFENIQTAYQAALAVAKENDRITVFGSF
HTVAEVSATL
NT seq
1293 nt
NT seq
+upstream
nt +downstream
nt
atgaaaacacttgacgattggttgtctcatctggaaaccgcacacagcgccggtttgatt
gacatgggtttgtcgcgcgtcggcgaagtgaaaacgcgcatgggtttggtgccgcaatgc
ccggtgattgtggtggcgggaaccaacggcaaaggttcggtatgcgcttttttgtcgcat
atttattcgcaggcaggctataaaaccggcacgctgaccagcccgcacctgttgcgtttc
aacgaacggattgccgtcaataccgagccggtatcggatgaggccattacggcttcgttc
gagcgtatcgaagcggcgcgcggtgatatttcgctgacttatttcgaattcaataccttg
gctgcggttgatgtgtttatgcgcgaaaaagtcgacgtgatgattttggaagtcggcttg
ggcggccgtttggacgcggtgaatatttttgacgcggattgtgcggtggtgacgtctgtc
gatctggatcatcaggcgtttttgggagacaacatcgaagcggtggcttatgaaaaagca
ggggtgttccgcccgtttaaacctgcggtttgcggccagaatccgccgcccgagtcgctg
aaaaagcatgccgaagacattcaggcggatttgttgttgattaaagacgatttcagcctg
accaagctggagcagcagcaatggtcgttccatttccatccgcaagaagcggtatcgcat
tttgccgaagggttcaaacgcaaccgcaatgcgctgccgattcccgctttgcgcggcagc
taccaattgggcaatgcggcttgtgctttggcggtgttggaatgtatgaatgcggttttg
ccggtggacatcggcgcaatcaagcgcggtttgctgctggtcaataatcccggccgtttc
caagtattgcccggccgtccgctggtgattttggatgtcggccacaatccgcatgcagcc
cgtgcgttgcgccaaagtctgattgcattgccgtttgccgaaaaacggattgccgtattc
agtattttggccgacaaggatatagacggcgtgttggaaaccgtgaaagaccaatttgac
gaatggtatatcgcaccgctacacctgccgcgcggcatgagtgtggaagcgttgaaaaac
aagctggcggagcatgatattgccgacaatgtcaaagcatttgaaaacattcagacggcc
tatcaggctgctttggcggttgcaaaggaaaatgatagaattaccgttttcggttcattt
cataccgttgccgaagtgtctgcaacgctgtaa
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