Nematolebias whitei (Rio pearlfish): 119421752
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Entry
119421752 CDS
T08042
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
nwh
Nematolebias whitei (Rio pearlfish)
Pathway
nwh04217
Necroptosis
nwh04620
Toll-like receptor signaling pathway
nwh04621
NOD-like receptor signaling pathway
nwh05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
nwh00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
119421752 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
119421752 (tyk2)
04621 NOD-like receptor signaling pathway
119421752 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
119421752 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nwh01001
]
119421752 (tyk2)
Enzymes [BR:
nwh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
119421752 (tyk2)
Protein kinases [BR:
nwh01001
]
Non-receptor tyrosine kinases
JAK family [OT]
119421752 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
SH2_1
Kinase-like
SH2
Kdo
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
119421752
NCBI-ProteinID:
XP_037545030
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All DBs
Position
15:35708917..35722048
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AA seq
1168 aa
AA seq
DB search
MSVRGWSRFFTSGGTLPGFSGPPQSQGIHVCLFWTKDGEKYLSHTSGDVTAEELCVLAAE
TVGITPLCHVLFALYDPQARCWYSPNHVFSSEQDSNVVLHYCMRFYFRNWHGLNEKEPTV
FRYALKSATDQTGSPLLDITSLEYLFAQAKYEFVNEVVEMEDIESEEELSRFKNESLGMA
VLHLSHLAIQENSTLQEVARKNSFLRCIPKSFAKHISKDNFLTKIRIRRVFSEFVRTFQQ
HTVDKGQLGEQEIMYKYISTLEHLAPCFGTETFLVTHLELREHSDGSSSYTNHSGGISKN
NPGASATHEIMVSGTKGIQWRKVHKQAQPNPYLRSNYLNYTMKSKQHSSEANGNAADSWT
SFCDFPEITLIDITESNVRISTQNNHCMEVEMNSSQEACSFISLLDGYYRLTADAHHYLC
REVAPARVVLSEANLLHGPMHDDFVLQKLKKEAAEEGTFLVRWSALDYHRIILAVLNKNE
NGSAPSHKQFRIQKKGSSFCMEGWDREFSSVKELTDSLKTFVLKSGSDSFTVRKCCLPKQ
GEISNLLVKRRGVDCGTHSDSLPLNLTQLRFHQIKDKDIIQEGHLGRGTRTNIYSGRLRV
WGGEDDVTESNNNFSRCKDIHVVLKILDQSHKDIALAFFETASLMSQLSHSHLVFVHGVS
VKGSENIMVEDYVEFGPLDLFLHKESASINAEWKLIVSLQLASALTYLETKHLVHGNVCA
KNILVARRGLEPGTSPFIKLSDPGIALNVLSREERLDRIPWIAPECVDSNAPIGCAADQW
SFGVTLLEICNNGLLPMSSSTLSEKERFYQQKGRLAEPSSQELSEFISWCLTYEPDARPS
FRTVLRELIEIIKRNPVLPPAIFPPPDPSMFQKRYLKKIRDLGEGHFGKVTLYMYDPCND
GTGELVAVKALKQENGNAPEGWMKEIEILKSLYHCNIVKYKGCCTEPGRQEVQLIMEYLP
LGSLREYLPKNKLSVPRCFMLAQQICQGMDYLHSKRYVHRDLAARNVLVENDCLVKIGDF
GLTKYIPEGEIYYRVHENGDSPVFWYAIECLKEQKFSFASDVWSFGVTLYEILTRCDYRQ
SPPTKFFEMTQESEGQMSLVALLNLLENNRRLPYPRDCPREVELVMEQCWKTNPADRPSF
EDLIKRFETIRRMYDWQFNTNFSMSQIC
NT seq
3507 nt
NT seq
+upstream
nt +downstream
nt
atgtccgtaagaggatggtccagatttttcacgtcaggaggaaccctcccaggcttcagt
ggtcccccccagtctcagggcatccatgtttgcctgttctggactaaagatggggagaaa
tatttgtctcacacaagcggagacgtcacggcggaggagctgtgcgtcttggctgcagaa
accgtagggataactcccctgtgccacgtgctgtttgcgttgtatgacccacaagcacga
tgctggtacagtccaaatcacgttttcagctcagaacaggactccaatgtagtgcttcac
tattgtatgaggttctactttcggaattggcacggacttaatgagaaggagccaactgta
tttcgatatgctctcaaatctgcgacggaccaaactggttcccctctgcttgatatcaca
tccttggagtatttatttgctcaggccaaatatgaatttgtgaatgaagttgtggaaatg
gaggacatagagtcagaggaggaactaagtcgcttcaaaaacgagagtctgggaatggct
gtgcttcacctctcgcaccttgcgatacaggaaaactcgaccttacaggaagtggcaaga
aaaaatagcttcctacgctgcattccaaaatcttttgccaaacacatatccaaggataac
tttctgactaaaatcaggatccggcgggtgttttccgaatttgtacggaccttccagcag
cacactgtggataaaggacaactgggtgagcaggagatcatgtataagtacatctctacc
ctggaacacttggctccatgctttggcacagagactttcctggtaacccacctggaactg
cgggaacacagcgacgggagcagctcttacacaaaccacagtggtggtatctcgaaaaat
aaccccggcgcgtcggccacgcatgaaataatggtgtccggcactaaggggattcagtgg
aggaaggtgcacaagcaggcacagccgaatccttatctcaggagcaattatttgaactac
acgatgaaatccaagcaacactccagcgaagcaaatgggaatgctgctgatagttggacc
tccttctgtgatttccctgaaataactctcatagacattactgaatctaatgtgcgcatt
agcactcagaacaatcactgcatggaggtagagatgaactccagccaggaggcctgctcc
ttcatctcccttctcgatggatactacagactgactgcagacgcccaccactatctttgc
cgtgaagtagctcccgccagggtagtgttgagcgaagcgaatctgctgcacggaccgatg
catgatgacttcgtgctgcaaaagctgaaaaaagaggcggcagaggagggaacgttcctc
gttcgatggagtgccctcgactatcaccgcatcatccttgctgtgctaaacaaaaatgag
aatgggtcggcgccgagccacaagcagtttcgtatccagaagaagggttcttctttctgc
atggagggctgggaccgagaattctccagcgtgaaggagctcactgatagcctcaaaact
tttgtgctcaagtctggttcggacagttttacagtcagaaaatgctgtttgccgaaacaa
ggagaaatatccaacctgctcgtgaaaaggcggggtgttgactgcggcactcactcggac
tccttgcctctaaacctgacgcagctccgcttccaccagattaaggacaaagatatcata
caggaagggcatttgggtcgtggaaccagaactaacatctactcaggacgtttgcgtgtg
tggggaggagaggatgatgtgactgagtccaacaacaacttttccagatgtaaggacatc
catgtggttctgaagattttagaccaaagccataaagatattgctctggcattttttgaa
actgcaagtctcatgagccagttatcccacagtcacctggtgtttgtacacggtgtatca
gttaaaggatctgaaaatattatggtggaagattatgtggagtttgggcctttagacctt
ttccttcacaaagaaagtgcctccataaacgctgagtggaaactgattgtttccttacaa
cttgcgagtgccctcacttatcttgagacgaaacacttggttcatggaaacgtctgtgct
aagaacattctggtggcgaggcggggcctagaacctggcacttcaccttttatcaagctg
agtgatccaggaatcgctctaaacgtcctctcaagagaagaacgtttggatcggatcccg
tggatcgcccccgagtgtgttgacagcaacgctcctatcggctgtgctgctgaccagtgg
agctttggtgtcacgctgctggaaatctgcaacaacggccttcttcccatgagtagcagc
acgttgtctgagaaagagcgattttatcagcagaagggtcgacttgctgaaccgtcctct
caggagctgtccgagttcatcagctggtgtttgacgtacgagccggatgcacggccttcg
ttccgcaccgtcctccgagagctcatagaaatcataaagagaaatcctgtacttcctcct
gccatcttcccaccaccagaccccagcatgttccagaagcgctacctgaaaaaaattagg
gatttaggcgagggacactttgggaaagtgacactgtacatgtatgacccctgcaacgat
gggaccggggaacttgtggcagtgaaagccttgaagcaagagaacggtaacgcacccgag
ggctggatgaaggagattgaaatcctgaaatccctctaccactgcaacatagtcaaatac
aaaggctgttgcactgagccaggaagacaagaggtccagctgataatggagtacctgccc
ctggggagcctgcgagagtatcttcctaaaaataagctcagtgtgccgcggtgtttcatg
cttgctcagcagatctgtcagggaatggactatttgcattcaaagcgctatgtgcatcga
gatctagccgcccgcaacgtcttggtggaaaatgattgtttggtaaagattggagacttt
ggcttgacgaaatacatccccgaaggagagatctactacagagttcatgaaaatggagac
agccctgtgttctggtatgccatcgagtgcttaaaggagcaaaagttttcttttgcctct
gacgtttggtcgtttggagtcactctgtatgagatcctgacccgctgtgactatcgccaa
agccctccaacaaagttctttgaaatgacccaggaatctgaaggacagatgagtttggtg
gcacttttaaacctgttggaaaacaatcggaggttaccttatcccagagactgcccacgc
gaggtggagttggtgatggaacagtgttggaaaacaaatcctgcagaccgaccatccttc
gaagacctcataaagaggtttgagaccatccgcagaatgtacgactggcagttcaacaca
aacttctccatgtctcagatttgctga
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