KEGG   Nematolebias whitei (Rio pearlfish): 119423986
Entry
119423986         CDS       T08042                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
nwh  Nematolebias whitei (Rio pearlfish)
Pathway
nwh04010  MAPK signaling pathway
nwh04012  ErbB signaling pathway
nwh04020  Calcium signaling pathway
nwh04510  Focal adhesion
nwh04520  Adherens junction
nwh04530  Tight junction
Brite
KEGG Orthology (KO) [BR:nwh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119423986 (erbb2)
   04012 ErbB signaling pathway
    119423986 (erbb2)
   04020 Calcium signaling pathway
    119423986 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    119423986 (erbb2)
   04520 Adherens junction
    119423986 (erbb2)
   04530 Tight junction
    119423986 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nwh01001]
    119423986 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:nwh04147]
    119423986 (erbb2)
   04090 CD molecules [BR:nwh04090]
    119423986 (erbb2)
Enzymes [BR:nwh01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     119423986 (erbb2)
Protein kinases [BR:nwh01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   119423986 (erbb2)
Exosome [BR:nwh04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   119423986 (erbb2)
CD molecules [BR:nwh04090]
 Proteins
  119423986 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Haspin_kinase DUF5849
Other DBs
NCBI-GeneID: 119423986
NCBI-ProteinID: XP_037547351
LinkDB
Position
17:complement(25746685..25778085)
AA seq 1292 aa
MEAARSLVFVGAVLLAVTGASGREVCLGTDMKLALPSSLENHYEILRLLYTGCQVVHGNL
EITHLHGNADLSFFQGIREVQGYVLVANVSVSLVPLDNLRIIRGSQLYNSSYALAVLDNT
LANQGLRTLRLRSLTEILLGSVYIWGNPQLCFPDPQRINWSDTLDEQDTKSKPPRLQFRA
PNCPSCSSACEERCWGETAQDCQTLTRINCASGCQRCKGPSPNDCCHRQCAAGCTGPKDT
DCLACRHVNEDGVCKENCPSAITYDQQAYQNKPNPKKKLNFGATCIEKCPYNYLVMEVAC
TLNCPLDNREKIIIEPDGNETQKCEKCEKDCSEACYGLGMDSLGVVGNQNVTMVTSANVE
QFTKCSKIFGSLAFRPQSFARDPVTNTSGLTLEQLSAFRNLEEITGYLYIDAWPEELTNL
SVFENLKVIRGRMRYMGVFSLAIQNLRIQSLGLRSLRRVSGSLVLLYNNSQLCYTNPQSW
KTLFHPTQGPHLIINHNKDPQICESEGHVCHSLCKGGCWGPGPGQCMSCKSFQRGTECVE
QCSIYQGARREYKNGSLCIACHKECRPVNGSASCHGQSAKDCVECQNNQDGELCVDRCPS
GGLKDRQAVWKYSNATGHCLPCNTNCTIPCAEVDERGCPVDITTGPGTTIAAAVGGVVLF
FILLALLVFYLRRQKKMRRKETVRRYLQEQELVEPLTPSGASPNQAQMRILKETELKKDR
VLGAGAFGTVYKGVWAPEGEHVTIPVAIKVLRENTSPKANKEILDEAYVMAGVTSPYVCR
LLGICLTSTVQLVTQLMPYGCLLDYVRENKDRIGSQFLLNWCVQIAKGMSYLEDIRLVHR
DLAARNVLVKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRRFTHQSD
VWSYGVTVWELMTFGSKPYNTIPARDIPNVLEGGERLPQPPICTIDVYMIMVKCWMIDPE
SRPKFKDLVQDFSLMARDPSRFLVIKNDEQMSTCSPVDSRFYRMLLEEGDNMGEIMDAEE
YLVPQPNLFARANGEEPQANGPSRHQSYRSRDQSLDLEPSIPAGPRTMYSSQGTLGRGQY
PTAPHGAGVANGVWPPLLDRSVSTGAQSDSVFLDAVPDGHSQPPISPGRYCKDPTYPIGS
QGDLETDGVEDFPRPPLHHSLPRRSHVHNHHQAMPEYVNQEMQDLRFVIPERPTTLPRKG
SKADRRVPNGLSSGHSMDKPGHLVSVNSTSSAFDNPYYLDLVAKAASGASAVDVPSALEN
DRGVSRHVNGFVTPTAENPEYLGLVDTWTGHS
NT seq 3879 nt   +upstreamnt  +downstreamnt
atggaggcggcgagaagtttggtgtttgtcggggccgtgctgctcgcagtgacgggagct
tcgggcagggaagtgtgtctgggtacagacatgaaactagcgctaccctccagcctggaa
aatcactacgagatcctgaggctactctacaccggctgccaggtcgtccatggcaacctg
gagattacacaccttcacggaaacgctgacctctccttctttcaggggatcagagaggtg
cagggttatgtactcgttgcaaatgtctcagtgagcttggtgcctctggacaaccttcgg
atcataagaggcagccagttgtacaattccagctatgccctggctgtgctggataacact
ctggccaatcagggcctgaggaccctccggctccgtagcctcacagagatcctgttgggt
agcgtgtatatttgggggaacccccagctgtgcttcccagacccccagcgcatcaattgg
agtgacactttggacgagcaggacaccaagtccaaaccgccccggctgcagtttcgggcc
cctaattgcccaagttgttcttctgcatgtgaagaaaggtgctggggagaaactgcgcag
gactgccagacattaactcgcattaactgtgcgagtggttgccagcgttgtaaaggtcct
tctcctaatgactgctgtcacagacagtgtgctgcaggctgcaccggacccaaggacaca
gactgcctggcatgtcgtcacgtcaacgaagacggtgtgtgtaaggaaaactgcccttca
gccatcacctacgaccaacaagcctatcagaacaaacccaaccccaagaagaagttaaac
tttggagccacctgcatcgagaagtgcccctataactatctggtcatggaagtggcttgc
actttgaattgccccctagacaatcgggaaaaaatcatcattgagcctgacggcaacgag
acgcagaaatgtgaaaagtgtgaaaaagactgctccgaagcgtgttatggtctgggtatg
gacagcttaggcgttgtgggcaatcagaacgtcaccatggtaacgtcggccaacgtggag
cagttcacaaagtgctcgaagattttcggaagtcttgcttttcgtccacagagctttgca
agggaccctgtgaccaacacctctggcctgactttggagcagctgagcgccttcaggaat
ctggaggaaatcacagggtatttgtacatcgatgcgtggccagaggagttgaccaacctg
tctgtgtttgagaacctgaaggtgatcagaggcaggatgcgctacatgggggtgttttct
ctcgccatccagaatctacgcatccagtctcttgggctccgctcacttcgcagagtcagt
ggaagtttggtcttgttgtacaacaactctcagttatgctacaccaatcctcagtcctgg
aaaactcttttccaccccacccaggggccacatctcatcattaaccacaacaaagacccc
caaatctgtgagagtgaggggcatgtatgtcactccctgtgtaaggggggctgttggggt
ccggggcccggccagtgcatgtcctgcaagtctttccaacgtggcactgagtgtgtagag
cagtgcagcatctaccagggggctaggcgtgagtacaagaatggatctttgtgtattgct
tgtcataaagagtgtcggcctgtcaacggctctgcttcctgccacggccagagtgcaaaa
gattgcgtggagtgtcaaaataatcaggacggagagttgtgtgtggatcgctgtcccagt
ggtgggctgaaggatcgtcaggctgtgtggaaatacagcaatgccacaggacactgtctg
ccctgcaacactaactgcactataccctgcgctgaagtggacgagagaggctgccccgtt
gatatcacgactggacccggtacaaccatcgccgctgctgtgggtggagtcgtgctgttt
ttcatcctgctggctctgctggtcttttatctgaggcggcagaaaaagatgaggaggaag
gagaccgtgaggaggtacctgcaggagcaggagctggtggagcctttaaccccgagcggt
gcgtctcccaatcaggctcaaatgcgcatcctgaaagagacggagctgaaaaaagaccga
gtgctgggcgcaggagcgtttggcacggtgtacaagggggtgtgggcgcctgaaggagaa
catgtgacaatacctgtggccattaaggtgttgagagagaacacctcacctaaagcaaat
aaagaaattcttgatgaggcctatgtgatggcaggggtcaccagcccgtacgtctgccgc
ctcctgggtatctgtctgacctccacggtgcagctggtcactcagctgatgccgtacggc
tgcctcctcgactacgtccgcgagaacaaggaccgcattggttctcagttcctcctcaac
tggtgtgtccagattgccaaggggatgagttatttggaggacattcgcttggtccacaga
gatctggctgctcgtaacgttctcgtaaagaatccaaaccatgtgaagatcacagacttc
ggtctggcccgtttgctggacatagatgagacggagtatcacgctgatggagggaaggtg
ccgataaaatggatggctttggagtccattctgcaccggaggttcactcatcagagtgac
gtctggagttatggagtgaccgtttgggagctgatgacgtttggctccaagccctacaac
acgatcccagcacgggacatcccaaatgttttggaaggaggagagcggctcccacagccc
ccaatctgcaccatcgacgtctacatgattatggtgaaatgttggatgattgatccagag
agcaggcccaagttcaaagatctggttcaggactttagtctcatggcaagagatccgtct
cgatttttagtcattaagaacgacgagcagatgagcacttgcagcccggtggacagcagg
ttttaccggatgcttctggaagagggggacaatatgggagaaataatggatgctgaggag
tacctggttccccaaccgaacctcttcgccagagctaacggagaggagccccaggccaac
gggccatccaggcaccagtcgtacaggagcagagatcagagcttggacctggagccctcc
atccctgctggccctcggaccatgtactcctctcagggtactcttggtcgtggtcagtat
cccaccgcaccacatggagcaggcgtagctaacggcgtgtggcctccgttgttggatcgc
agcgtctcaacaggagcccagtccgactccgtcttcctggatgcggttccagatggacac
tcgcagcccccgatcagccctggacgctactgcaaagaccctacttatcccatcgggagc
cagggcgacctggaaactgacggggtggaggacttccctcgtcctccccttcatcactct
ctgcccaggcggagtcatgtccacaaccaccatcaagccatgccagagtacgttaaccag
gagatgcaggatctcaggtttgtaatccccgagcggcccaccactcttccacgtaaaggc
tctaaagcagacagacgagtgcccaatggtctgagctctggtcacagcatggacaagcca
ggtcacctggtatctgtgaactccacgtcctctgcctttgacaacccgtactacctggac
cttgtagccaaagctgcctccggggcttcagcagtggacgtcccttcagctttagagaac
gaccggggagttagcaggcacgtgaacggtttcgtcactcccactgcagaaaatccagag
tatctcggactggtggacacatggactggacatagttga

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