Nocardia wallacei: NWFMUON74_02870
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Entry
NWFMUON74_02870 CDS
T07034
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
nwl
Nocardia wallacei
Pathway
nwl00290
Valine, leucine and isoleucine biosynthesis
nwl00620
Pyruvate metabolism
nwl01100
Metabolic pathways
nwl01110
Biosynthesis of secondary metabolites
nwl01210
2-Oxocarboxylic acid metabolism
nwl01230
Biosynthesis of amino acids
Module
nwl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nwl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
NWFMUON74_02870 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NWFMUON74_02870 (leuA)
Enzymes [BR:
nwl01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
NWFMUON74_02870 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
BCK52515
UniProt:
A0A7G1KC25
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Position
318841..320538
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AA seq
565 aa
AA seq
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MPTFRYRPFAEEVEPVTLPDRTWPDKVIDRAPAWCAVDLRDGNQALIDPMSPARKRRMFD
LLVRMGYKEIEVGFPSASQTDFDFVREIIEDGAVPDDVTIQVLTQCRPELIERTFLACQG
APNVIVHFYNSTSILQRRVVFRADRDAVKKIATDAATLCLEIEQRYPDTNWRYEYSPESY
TGTELEYAREVCDAVSAIIAPTPDKPMIINLPATVEMATPNVYADSIEWMSRNLARRDSI
VLSLHPHNDRGTAVAAAELGYMAGADRIEGCLFGNGERTGNVCLVTLGMNLFSRGVDPQI
DFSDIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDAMKAQADSDGRD
VEDITWEVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKTDHGLALPRRLQIEFSQA
IQRITDGEGGEVSPKAMWDVFAEEYLNPILPLERMRQKVSAAETDGGTDHIDAVVKVEGT
EQEISGEGNGPLAAFVDALATIGYDVRVLDYSEHAMSAGDDAQAAAYVECAVGDQVSWGV
GIATSITTASLRAVVSAVNRAHRGS
NT seq
1698 nt
NT seq
+upstream
nt +downstream
nt
atgccgaccttccggtaccggccgttcgccgaggaggtcgagcccgtcacgctgcccgac
cgcacgtggccggacaaggtcatcgatcgcgccccggcctggtgtgccgtggacctgcgc
gacggcaaccaggcgctgatcgacccgatgagcccggcccgcaagcgccgcatgttcgat
ctgctggtgcggatgggctacaaggagatcgaggtcggtttcccctccgccagccagacc
gatttcgacttcgtccgcgagatcatcgaggacggcgcggttccggacgacgtcaccatc
caggtgctgacccagtgccgcccggagctgatcgagcgcaccttcctggcctgccagggc
gcaccgaacgtgatcgtccacttctacaactccacctcgatcctgcagcggcgggtcgtg
ttccgggccgaccgtgacgcggtgaagaagatcgccaccgacgccgcgacgctgtgcctg
gagatcgagcagcgctaccccgacacgaactggcgctacgaatacagcccggagtcctac
accggcaccgagctggagtacgcccgcgaggtgtgtgacgcggtctcggcgatcatcgca
ccgactcccgacaagccgatgatcatcaacctgcccgcgacggtcgagatggcgaccccg
aacgtctacgccgactcgatcgagtggatgagccgcaacctggcccggcgcgactcgatc
gtgctgtcgctgcatccgcacaacgatcgcggcaccgccgtggccgccgccgagctgggc
tacatggcgggtgcggaccgcatcgagggctgcctgttcggcaacggcgagcgcaccggc
aacgtatgcctggtcacgctgggcatgaacctgttctcgcgcggcgtggatccgcagatc
gacttctccgacatcgacgagatccgccgcaccgtcgaatactgcaaccagctgcccgtg
cacgagcggcacccctacggcggcgatctggtctacaccgccttctccggcagccaccag
gacgccatcaacaagggcttggacgcgatgaaggcgcaagcggactcggatggccgcgac
gtcgaggacatcacctgggaggtcccgtacctgcccatcgaccccaaggacgtcgggcgc
acctacgaggccgtgatccgggtgaactcgcagtccggcaagggcggcgtcgcctacatc
atgaagaccgaccacggcctggccctgccgcgccggctgcagatcgagttctcgcaggcg
atccagcggatcaccgacggcgagggcggtgaggtctcgcccaaggcgatgtgggacgtc
ttcgccgaggagtacctgaacccgatcctgccgctggaacgcatgcggcagaaggtgtcc
gccgcggagaccgacggcggtaccgaccacatcgatgccgtggtcaaggtggagggcacc
gagcaggagatctccggcgagggcaacggaccgctcgcggcgttcgtcgacgcgctggcg
accatcggatacgacgtgcgggtgctggactactccgagcacgccatgtccgccggtgac
gacgcgcaggccgccgcctacgtggaatgcgccgtcggcgaccaggtgtcgtggggggtg
ggcatcgcgacctccatcaccaccgcctcgctgcgcgcggtggtctccgccgtcaaccgg
gcgcaccggggcagctga
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