KEGG   Nocardia wallacei: NWFMUON74_02870
Entry
NWFMUON74_02870   CDS       T07034                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
nwl  Nocardia wallacei
Pathway
nwl00290  Valine, leucine and isoleucine biosynthesis
nwl00620  Pyruvate metabolism
nwl01100  Metabolic pathways
nwl01110  Biosynthesis of secondary metabolites
nwl01210  2-Oxocarboxylic acid metabolism
nwl01230  Biosynthesis of amino acids
Module
nwl_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:nwl00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    NWFMUON74_02870 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    NWFMUON74_02870 (leuA)
Enzymes [BR:nwl01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     NWFMUON74_02870 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: BCK52515
UniProt: A0A7G1KC25
LinkDB
Position
318841..320538
AA seq 565 aa
MPTFRYRPFAEEVEPVTLPDRTWPDKVIDRAPAWCAVDLRDGNQALIDPMSPARKRRMFD
LLVRMGYKEIEVGFPSASQTDFDFVREIIEDGAVPDDVTIQVLTQCRPELIERTFLACQG
APNVIVHFYNSTSILQRRVVFRADRDAVKKIATDAATLCLEIEQRYPDTNWRYEYSPESY
TGTELEYAREVCDAVSAIIAPTPDKPMIINLPATVEMATPNVYADSIEWMSRNLARRDSI
VLSLHPHNDRGTAVAAAELGYMAGADRIEGCLFGNGERTGNVCLVTLGMNLFSRGVDPQI
DFSDIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDAMKAQADSDGRD
VEDITWEVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKTDHGLALPRRLQIEFSQA
IQRITDGEGGEVSPKAMWDVFAEEYLNPILPLERMRQKVSAAETDGGTDHIDAVVKVEGT
EQEISGEGNGPLAAFVDALATIGYDVRVLDYSEHAMSAGDDAQAAAYVECAVGDQVSWGV
GIATSITTASLRAVVSAVNRAHRGS
NT seq 1698 nt   +upstreamnt  +downstreamnt
atgccgaccttccggtaccggccgttcgccgaggaggtcgagcccgtcacgctgcccgac
cgcacgtggccggacaaggtcatcgatcgcgccccggcctggtgtgccgtggacctgcgc
gacggcaaccaggcgctgatcgacccgatgagcccggcccgcaagcgccgcatgttcgat
ctgctggtgcggatgggctacaaggagatcgaggtcggtttcccctccgccagccagacc
gatttcgacttcgtccgcgagatcatcgaggacggcgcggttccggacgacgtcaccatc
caggtgctgacccagtgccgcccggagctgatcgagcgcaccttcctggcctgccagggc
gcaccgaacgtgatcgtccacttctacaactccacctcgatcctgcagcggcgggtcgtg
ttccgggccgaccgtgacgcggtgaagaagatcgccaccgacgccgcgacgctgtgcctg
gagatcgagcagcgctaccccgacacgaactggcgctacgaatacagcccggagtcctac
accggcaccgagctggagtacgcccgcgaggtgtgtgacgcggtctcggcgatcatcgca
ccgactcccgacaagccgatgatcatcaacctgcccgcgacggtcgagatggcgaccccg
aacgtctacgccgactcgatcgagtggatgagccgcaacctggcccggcgcgactcgatc
gtgctgtcgctgcatccgcacaacgatcgcggcaccgccgtggccgccgccgagctgggc
tacatggcgggtgcggaccgcatcgagggctgcctgttcggcaacggcgagcgcaccggc
aacgtatgcctggtcacgctgggcatgaacctgttctcgcgcggcgtggatccgcagatc
gacttctccgacatcgacgagatccgccgcaccgtcgaatactgcaaccagctgcccgtg
cacgagcggcacccctacggcggcgatctggtctacaccgccttctccggcagccaccag
gacgccatcaacaagggcttggacgcgatgaaggcgcaagcggactcggatggccgcgac
gtcgaggacatcacctgggaggtcccgtacctgcccatcgaccccaaggacgtcgggcgc
acctacgaggccgtgatccgggtgaactcgcagtccggcaagggcggcgtcgcctacatc
atgaagaccgaccacggcctggccctgccgcgccggctgcagatcgagttctcgcaggcg
atccagcggatcaccgacggcgagggcggtgaggtctcgcccaaggcgatgtgggacgtc
ttcgccgaggagtacctgaacccgatcctgccgctggaacgcatgcggcagaaggtgtcc
gccgcggagaccgacggcggtaccgaccacatcgatgccgtggtcaaggtggagggcacc
gagcaggagatctccggcgagggcaacggaccgctcgcggcgttcgtcgacgcgctggcg
accatcggatacgacgtgcgggtgctggactactccgagcacgccatgtccgccggtgac
gacgcgcaggccgccgcctacgtggaatgcgccgtcggcgaccaggtgtcgtggggggtg
ggcatcgcgacctccatcaccaccgcctcgctgcgcgcggtggtctccgccgtcaaccgg
gcgcaccggggcagctga

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