Ornithorhynchus anatinus (platypus): 100073433
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Entry
100073433 CDS
T01045
Symbol
VAV2
Name
(RefSeq) guanine nucleotide exchange factor VAV2 isoform X1
KO
K05730
guanine nucleotide exchange factor VAV
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa04015
Rap1 signaling pathway
oaa04024
cAMP signaling pathway
oaa04062
Chemokine signaling pathway
oaa04510
Focal adhesion
oaa04650
Natural killer cell mediated cytotoxicity
oaa04660
T cell receptor signaling pathway
oaa04662
B cell receptor signaling pathway
oaa04664
Fc epsilon RI signaling pathway
oaa04666
Fc gamma R-mediated phagocytosis
oaa04670
Leukocyte transendothelial migration
oaa04810
Regulation of actin cytoskeleton
oaa05135
Yersinia infection
oaa05205
Proteoglycans in cancer
oaa05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
100073433 (VAV2)
04024 cAMP signaling pathway
100073433 (VAV2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100073433 (VAV2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100073433 (VAV2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100073433 (VAV2)
04660 T cell receptor signaling pathway
100073433 (VAV2)
04662 B cell receptor signaling pathway
100073433 (VAV2)
04664 Fc epsilon RI signaling pathway
100073433 (VAV2)
04666 Fc gamma R-mediated phagocytosis
100073433 (VAV2)
04670 Leukocyte transendothelial migration
100073433 (VAV2)
04062 Chemokine signaling pathway
100073433 (VAV2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100073433 (VAV2)
09171 Infectious disease: bacterial
05135 Yersinia infection
100073433 (VAV2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100073433 (VAV2)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RhoGEF
SH3_2
CAMSAP_CH
CH
SH3_1
SH3_9
SH2
SOS1_NGEF_PH
C1_1
PH
RHG20_PH
DUF7145
CDC24
SH2_2
C1_2
PH_10
PHD
Motif
Other DBs
NCBI-GeneID:
100073433
NCBI-ProteinID:
XP_028918838
Ensembl:
ENSOANG00000002845
UniProt:
A0A6I8NTR5
LinkDB
All DBs
Position
4:complement(37570545..37944647)
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AA seq
892 aa
AA seq
DB search
MEQWRQCGRWLIDCKVLPANHRVVWPAAGVFDLAQALRDGVLLCQLLHNLAPGSIDLKDI
NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISTVARLSLHSI
AQNKGIRPFPSEETAENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIKVEV
QQPMIRYMQKMGMTEDDKRNCCLLEIQETEAKYYKTLEDIEKNYMNPLKLVLSPLDMAAI
FINLEDLIKVHNSFLRAIDVSMMAGGSSLAKVFLEFKERLLIYGEYCSHMEIAQNTLNHL
IANREDFRQKVEECTLKVQEGKFKLQDLLVVPMQRVLKYHLLLKELLSHSTDRPERLQLK
EALEAMQDLAMYINEVKRDKETLKKISEFQSSIENLQVKLEDFGRPKIDGELKVRSIVNH
TKQDRYLFLFDKVVIVCKRKGYNYELKEIIELLFHKMTDDPMNNKDIKKSHGKMWSYGFY
LIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPEKANANHHNFQMYTFDKTTNCKAC
KMFLRGTFYQGYLCTKCGVGAHKECLEVIPPCKIRSLGYICPQKHICHCSPVDQDALSIG
PGPKMVAIQNYHGNPAPPGKSVLAFQTGDVIELLRGDPDSQWWEGRLIHTKKTGFFPSSS
VKPCPVDGRPPSSRPPSREIDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAER
FAISIKFNDEVKHIKVVEKDNWIHITEAKKFESLLELVEYYQCHSLKESFKQLDTTLKYP
YKSRERSASRASTRSPASCASYNFSFLSPQGLNFSSQGPSTPFWSVFTPRVIGTAVARYN
FAARDMRELSLREGDVVKIYSRIGGDQGWWKGETNGRIGWFPSTYVEEEGVQ
NT seq
2679 nt
NT seq
+upstream
nt +downstream
nt
atggagcagtggcggcaatgcggccgctggctcatcgactgcaaggtgctgcccgccaac
caccgggtggtgtggccggccgccggggtcttcgacctggcccaggccctccgggacggc
gtcctcctctgccagctcctccacaacctcgcccccggatccatcgacctcaaggacatc
aatttcaggccgcagatgtcccagtttctctgcttgaagaatattcggaccttcctgaaa
gtctgccacgataaatttgggttaaggaacagtgagctgtttgatccttttgacctcttt
gatgtccgagattttggaaaggtgatttctacagtggccaggctgtccctacatagtatt
gctcagaacaaaggaatcaggcccttcccttcagaagagacagcagagaacgacgatgac
gtgtaccggagcttggaggagttggctgatgaacatgatctgggagaggatatttatgat
tgtgtcccctgtgaagatgaaggtgatgacatctatgaagatattattaaagtggaagtt
cagcagcccatgattagatatatgcagaaaatgggaatgacagaggatgacaagagaaat
tgctgcttgctagagattcaggaaactgaggccaaatactacaaaacacttgaagacatt
gaaaagaactacatgaatcctttgaagctggtactgagccctctcgacatggcagctatt
tttatcaatttggaggacctaattaaagtgcacaacagttttctacgggccatcgacgtc
tcgatgatggctggaggaagcagcctggcaaaagtttttctggaattcaaagaaaggctg
ttgatttacggagagtactgcagccacatggaaatcgcccagaatacgttgaaccacctc
attgccaatcgggaggattttaggcagaaagtggaggagtgcactctgaaggtccaggag
ggaaagttcaaattgcaagacttgctggtggtgccgatgcagcgagtgctcaaataccat
cttctcttaaaggaactcctcagtcactccaccgatcgtcctgaaagactgcagctcaag
gaggccttggaagccatgcaggatttggccatgtatatcaatgaagttaaacgggacaaa
gagacattaaagaaaatcagtgaatttcagagttctatagaaaacttgcaggtaaaactg
gaagactttggcaggccgaagatcgatggggaattaaaagttcggtcgatagtaaaccac
accaagcaagacaggtatctatttttgtttgataaagtggtgattgtctgcaagaggaaa
ggctacaattatgagctgaaggagatcatcgagctgctgtttcataagatgacggatgac
cctatgaacaataaagacattaaaaagtctcatggaaaaatgtggtcctacggattctac
ttaattcatctccagggaaagcagggcttccagtttttctgcaagaccgaagacatgaaa
aggaaatggatggagcagtttgaaatggcaatgtccaacatcaaacctgagaaagccaat
gcaaatcaccacaacttccagatgtatacgttcgataaaacgaccaactgcaaagcctgc
aagatgtttttaagagggaccttctatcagggctatctttgcacgaaatgtggagtcgga
gcccataaagaatgtttagaagttattccaccctgcaagatcaggtctctgggatacata
tgtccacaaaaacatatctgccactgttctcctgtggaccaggacgctttaagtatagga
cccggtcccaaaatggtggccatccagaactatcacggcaacccagctcctccagggaag
tcggtgctcgcgtttcagacaggagatgtcatcgagctgctgaggggagacccggactca
cagtggtgggaaggacggctaatacacaccaagaagactgggttttttcctagttcatct
gtgaagccctgccctgtggatggaaggccccccagcagcaggcccccatcgagggagata
gactacaccgcgtacccttggtttgcaggcaacatggagcgacagcagactgacaacttg
ttgaaatcccacgcgagcgggacgtacctgatccgagagagacccgcagaagcagagcgc
tttgcaataagtattaagtttaatgatgaggtgaagcacattaaggtggtcgaaaaagac
aactggattcatatcacagaagccaaaaagtttgaaagcctcttggaattggtggaatac
taccagtgccattcgctcaaggagagtttcaagcagctggacaccacactgaagtatccc
tataaatcccgggaacggtcagcttctcgggcatccaccaggtctccagcctcctgtgct
tcctacaacttttcttttctcagtcctcagggtctcaacttttcctctcagggtccctcc
actcctttctggtcagtgttcacgccccgggtcatcggaacagcagtggccaggtacaac
tttgcagcccgggacatgagggagctctccctgcgggagggagacgtggtgaaaatctac
agccgcatcggcggggaccagggctggtggaaaggagaaaccaacggcaggattggctgg
tttccatcgacctatgtggaggaagagggagtgcagtga
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