Ornithorhynchus anatinus (platypus): 100073740
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Entry
100073740 CDS
T01045
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa04020
Calcium signaling pathway
oaa04022
cGMP-PKG signaling pathway
oaa04024
cAMP signaling pathway
oaa04148
Efferocytosis
oaa04260
Cardiac muscle contraction
oaa04261
Adrenergic signaling in cardiomyocytes
oaa04380
Osteoclast differentiation
oaa04919
Thyroid hormone signaling pathway
oaa04972
Pancreatic secretion
oaa05010
Alzheimer disease
oaa05017
Spinocerebellar ataxia
oaa05022
Pathways of neurodegeneration - multiple diseases
oaa05410
Hypertrophic cardiomyopathy
oaa05412
Arrhythmogenic right ventricular cardiomyopathy
oaa05414
Dilated cardiomyopathy
oaa05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
100073740 (ATP2A2)
04024 cAMP signaling pathway
100073740 (ATP2A2)
04022 cGMP-PKG signaling pathway
100073740 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100073740 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100073740 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
100073740 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
100073740 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
100073740 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
100073740 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100073740 (ATP2A2)
05017 Spinocerebellar ataxia
100073740 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
100073740 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100073740 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
100073740 (ATP2A2)
05414 Dilated cardiomyopathy
100073740 (ATP2A2)
05415 Diabetic cardiomyopathy
100073740 (ATP2A2)
Enzymes [BR:
oaa01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
100073740 (ATP2A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
100073740
NCBI-ProteinID:
XP_028914629
Ensembl:
ENSOANG00000004781
UniProt:
A0A6I8PPD5
LinkDB
All DBs
Position
2:18916334..18984360
Genome browser
AA seq
1042 aa
AA seq
DB search
MENAHTKTVEEVLAHFSVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDRVEGDSCCLSEFTITGSTYAPLGEVHKDDKQVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIERCTHIRVGSTKMPMTQGI
KHKIMSVIREWGSGRDTLRCLALATHDNPPRREEMNLDDSANFIKYETNLTFVGCVGMLD
PPRTEVASSIKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGSEEDVSSKAFTGREFDEL
APPAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRITFYQLSHFLQCKDDNPDFEGVDCVIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLMRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVRPSTKPCSFSACTEGISWPFVL
IIMPLVIWLYSTDTNFSDMFWS
NT seq
3129 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcacacacaaagaccgtggaggaggtgttggctcatttcagcgtcaacgag
agcaccgggctcagcctcgagcaggtcaagaagctcaaggagagatggggttccaacgaa
ttaccagcggaagaaggaaaaacattactggagcttgtgattgaacagtttgaagactta
ttagttagaattttgttgctggcagcttgtatatcttttgttttggcatggtttgaagaa
ggggaagaaacaattacagcctttgtagagccttttgtaatcttgcttatattggtagcc
aatgcaattgtgggcgtgtggcaggaaagaaatgctgaaaatgccatcgaagctcttaaa
gaatatgaacctgaaatgggaaaagtttatcgacaggaccgaaagagtgtacaacggatt
aaagcgaaagacatagtccctggtgatattgtagaaatagctgttggtgataaagttcct
gctgatataagattaacttccatcaaatctacaactttacgagtagaccagtcaattctc
acaggtgaatctgtatctgtaattaagcacactgatccagtgcccgatcctcgtgctgta
aaccaagataagaagaatatgctgttttctggtacaaacattgctgctggaaaagcaatg
ggagtggtggtagcaactggagtgaacactgaaattggcaagatccgggatgaaatggtg
gctaccgaacaggagagaacacccctccagcagaaactggatgagtttggagagcagttg
tccaaagttatctccctcatttgcattgcagtttggataataaacattggacatttcaat
gatccagttcatggtggctcttggattagaggtgctatctattactttaaaattgcagtt
gctcttgctgttgctgctattccagaaggtctccctgctgtcattaccacctgcttggct
cttggaactcggagaatggcaaaaaagaacgctattgttagaagtctcccatctgtagaa
accctgggttgtacgtctgttatttgctccgacaagacaggcacccttacaaccaatcag
atgtcagtttgcaggatgtttattctggacagagtggaaggagatagctgctgcctgagt
gagttcaccataactggatcaacgtatgctccacttggagaagtgcataaagatgacaaa
caagtgaaatgtcatcagtatgatggccttgtcgaattagcaacaatttgtgcactttgt
aatgattctgctctggattacaatgaggcaaaaggagtgtatgaaaaggttggggaagct
acagaaaccgcactgacctgcctggttgagaagatgaacgtatttgacaccgaactgaaa
ggtctctccaaaattgaacgtgcaaatgcatgcaattcggtcataaaacaactgatgaag
aaagaattcactctagagttttcaagggacagaaagtccatgtctgtctattgcacacca
aataaacctagccggacttccatgagcaagatgtttgttaagggtgcccctgaaggtgta
attgagagatgtacacacattcgtgttggaagtactaaaatgcctatgactcaaggaatc
aagcataagatcatgagtgttattcgagaatggggctctggccgagatacgctgcgttgt
ttagctctagcaactcacgacaatccaccgagaagagaagaaatgaacctggatgactct
gccaattttattaaatacgagaccaatctgacttttgttggttgcgtgggtatgctggat
ccaccaagaactgaagtagcttcgtccataaagctctgtaggcaagccggtatccgtgtc
attatgattactggagataacaaaggcactgcagtggccatctgtcgtcgaattggtatc
tttgggagtgaagaagatgtttcttcaaaggcttttacaggacgagagtttgatgagctt
gctcccccggcacagagagatgcttgcctaaatgctcgttgctttgctcgggtagagccg
tcccacaagtctaagattgtggaattccttcagtcttttgatgagatcacagctatgact
ggtgatggtgtaaatgatgctcctgccctgaagaaagcagagattggcattgctatgggg
tctggcactgctgtagcaaagactgcctctgagatggtgttggccgatgacaacttctcc
acaatcgtagctgccgttgaagaaggccgagcaatctacaataacatgaaacagttcatt
cgctacctcatctcttctaatgttggcgaggttgtttgtattttcctgactgctgctctt
ggttttccggaggctttgattccagtccaactactctgggtgaatcttgtgacagatggc
ctgcctgctactgctctgggatttaacccccctgatctggacatcatgaataagcccccc
cgcaatcctaaagagcctctgatcagtgggtggctcttcttccgttatctagctatcgga
tgttatgttggagctgctacagtgggtgctgctgcatggtggttcattgctgctgatggt
ggcccaagaattaccttctaccagctgagccatttcttgcagtgcaaagatgacaaccct
gactttgaaggcgttgattgtgtgatctttgagtccccgtacccaatgacgatggccctg
tcggttctggttactatagagatgtgtaatgctcttaacagcttatcagaaaatcagtca
ttaatgaggatgcctccatgggaaaacatctggctggtgggctctatttgtttatccatg
tcactccatttcctaattctctatgtcgaaccattgccgctcatcttccagatcacacct
ctgaatgtgacccagtggctgatggtgctgaaaatatcattacctgtgattctgatggat
gagacacttaagtttgtggcccgtaactatctggaacctggtaaagagtgtgtgcgacct
tccaccaaaccgtgttctttctcggcatgcaccgaagggatttcctggccgtttgtgctt
atcataatgccattggttatctggctttacagtacagacactaactttagtgatatgttc
tggtcttga
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