KEGG   Ornithorhynchus anatinus (platypus): 100073765
Entry
100073765         CDS       T01045                                 
Symbol
MLH1
Name
(RefSeq) DNA mismatch repair protein Mlh1 isoform X1
  KO
K08734  DNA mismatch repair protein MLH1
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa01524  Platinum drug resistance
oaa03430  Mismatch repair
oaa03460  Fanconi anemia pathway
oaa05200  Pathways in cancer
oaa05210  Colorectal cancer
oaa05213  Endometrial cancer
oaa05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03430 Mismatch repair
    100073765 (MLH1)
   03460 Fanconi anemia pathway
    100073765 (MLH1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100073765 (MLH1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100073765 (MLH1)
   05226 Gastric cancer
    100073765 (MLH1)
   05213 Endometrial cancer
    100073765 (MLH1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100073765 (MLH1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:oaa03400]
    100073765 (MLH1)
DNA repair and recombination proteins [BR:oaa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   MMR (mismatch excision repair)
    MutL homologs
     100073765 (MLH1)
SSDB
Motif
Pfam: Mlh1_C DNA_mis_repair HATPase_c_3 HATPase_c
Other DBs
NCBI-GeneID: 100073765
NCBI-ProteinID: XP_028904812
Ensembl: ENSOANG00000015305
UniProt: F6PYZ7
LinkDB
Position
21:5369921..5410984
AA seq 745 aa
MALVAGVIRRLDEAVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVTVKEGGLKLIQ
IQDNGTGIRKDDLAIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTVTTKTA
DGKCAYRASYSDGKLKSPPRPCAGNQGTLITVEDLFYNVGTRRKALKNPSEEYGKILDVV
GRYSVHNSGISFLVRKQGETAADIRTLPDATTVDNIRSVFGCVVSRELIEVGCDDPKLAF
KMKGYISNANYSVKKCVFLLFINHRLVDSTALKRAIENVYVAYLPKNTHPFLYLSLEIAP
QNVDVNVHPTKHEVHFLHEDSILERVQQHIDGRLLASNSSRMFFTQTLLPGLADPSGEEA
TQSSAGGGPPSSSSSSSSSQGPGGKVSAHRTVRTDARDQKLEAFLQPGGGPPAAPLASAP
RDPAPGRREADAAEPEDRPDEAAGSLDPAAGTPGSDRGRKRAREDSDGETEEEEGGQEMT
AGGAPRRRVINLTSILTLREEIDERGHRPLRELLHGHSFVGCMSPQWALAQFQTKLYLLN
TTKLSEELFYQILIYDFANFGVLRLSEPAPLHTLAMLALDGAESGWTEEDGPKEGLADYI
VEFLKKKAEMLADYFSLEIDEEGNLIGLPLLIDNYIPPLEGLPMFILRLATEVNWDEEKE
CFESLSKECAMFYSIRKQYVAEDPTPSDSQGEMPGSSPVSWKWTVEHVIYKAFRSHVLPP
KHLTEDGTILQLANLPDLYKVFERC
NT seq 2238 nt   +upstreamnt  +downstreamnt
atggcgctggtagccggcgtcatccggcggctggacgaggccgtggtcaaccgcatcgcc
gccggggaggtcatccagcgccccgccaacgccatcaaggagatgatagagaactgcttg
gatgccaaatccacaagtatccaggtgacggttaaagaaggagggctgaaattaattcag
atccaagacaatggcaccggaatcaggaaagacgacttggccatcgtgtgtgaaaggttc
accacaagcaagctgcagtctttcgaagacctggctagtatttctacctatggcttcagg
ggcgaggccctggccagcataagtcacgtggcccacgtgacggtgaccacgaaaacggcg
gatggcaaatgtgcctacagagccagttattccgacggcaaactgaagtcgccccccaga
ccttgcgccgggaaccaggggaccctgatcacggtcgaggacctgttctacaacgtaggc
accaggaggaaagcgttaaaaaatcccagcgaagagtacgggaagatcctggacgtcgtc
ggcagatactccgtacacaactcgggcatcagtttcttagtgagaaaacaaggggagacg
gcggccgacatccgcaccctgcccgacgccaccacggtggacaacatccgctccgtcttc
ggatgcgtcgtcagccgggagttgatagaagtgggatgcgacgaccccaagctggccttc
aagatgaagggctacatctccaacgccaactactccgtgaagaagtgcgtcttcttactc
ttcatcaatcatcggctggtggattccacggcgctgaagagggctatcgaaaacgtctac
gtggcctatctgcccaaaaacacccacccgttcctctacctcagcctggagatcgccccc
cagaacgtggacgtgaacgtccacccgaccaagcacgaggtccacttcctccacgaggac
agcatcctggagcgggtgcagcagcacatagacggccgcctcctggcctccaactcctcc
cggatgttcttcacccagactctgctgcccggcctcgccgacccttccggggaggaggcc
acgcagtcgtccgctggcggcggtcccccctcctcgtcgtcgtcgtcgtcgtcgtcccag
ggccccggcggcaaggtgtccgcccaccggacggtccgcaccgacgcccgggaccagaag
ctcgaggccttcctgcagcccgggggcggcccgcccgcggccccgctcgcctccgccccc
cgggaccccgcgcccgggaggcgggaggccgacgcggcggagcccgaggaccgcccggat
gaggccgcggggagcctggaccccgccgcggggacgcccggctcggatcggggcagaaag
agggcgcgggaggattcagacggagagacggaggaggaggaaggcggccaggagatgacg
gcgggaggcgcccctcgccggagggtcatcaacctgaccagcatcctcaccctccgggaa
gagatcgacgagcgcggccatcggcccctccgggagctgctgcacggtcactcgttcgtg
ggctgcatgagtccgcagtgggcgctggcccagttccagaccaagctgtacctgctcaac
accaccaaactcagcgaagagctgttctaccagattctcatctacgactttgccaacttc
ggagttctgaggttgtcggagccggccccactccacactctggccatgctggccttggac
ggcgcggaaagcggctggacggaggaagacggccccaaggaaggcctggccgactacatc
gtggagttcctgaagaagaaggcggagatgctggcggactacttctcgctggagatcgac
gaggaaggaaacctgataggactgccccttctgatcgacaactacatccccccgcttgag
ggactcccgatgttcatccttcgcttggccaccgaggtcaactgggatgaagaaaaggag
tgtttcgagagcctcagtaaagaatgcgccatgttttactccatcaggaagcaatacgtc
gcggaggaccccacgccctcggactctcagggtgagatgcccggctcctccccggtgtcg
tggaagtggacggtggagcacgtcatctacaaggccttcaggtcccacgtccttccccct
aaacacctcactgaggacggcaccatcctccagctggccaatcttccagatctgtacaaa
gtcttcgagcggtgctga

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