Ornithorhynchus anatinus (platypus): 100077556
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Entry
100077556 CDS
T01045
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa01521
EGFR tyrosine kinase inhibitor resistance
oaa01522
Endocrine resistance
oaa04010
MAPK signaling pathway
oaa04014
Ras signaling pathway
oaa04015
Rap1 signaling pathway
oaa04066
HIF-1 signaling pathway
oaa04068
FoxO signaling pathway
oaa04081
Hormone signaling
oaa04114
Oocyte meiosis
oaa04140
Autophagy - animal
oaa04144
Endocytosis
oaa04150
mTOR signaling pathway
oaa04151
PI3K-Akt signaling pathway
oaa04152
AMPK signaling pathway
oaa04211
Longevity regulating pathway
oaa04213
Longevity regulating pathway - multiple species
oaa04510
Focal adhesion
oaa04520
Adherens junction
oaa04550
Signaling pathways regulating pluripotency of stem cells
oaa04730
Long-term depression
oaa04913
Ovarian steroidogenesis
oaa04914
Progesterone-mediated oocyte maturation
oaa05200
Pathways in cancer
oaa05202
Transcriptional misregulation in cancer
oaa05205
Proteoglycans in cancer
oaa05214
Glioma
oaa05215
Prostate cancer
oaa05218
Melanoma
oaa05224
Breast cancer
oaa05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100077556 (IGF1R)
04014 Ras signaling pathway
100077556 (IGF1R)
04015 Rap1 signaling pathway
100077556 (IGF1R)
04066 HIF-1 signaling pathway
100077556 (IGF1R)
04068 FoxO signaling pathway
100077556 (IGF1R)
04151 PI3K-Akt signaling pathway
100077556 (IGF1R)
04152 AMPK signaling pathway
100077556 (IGF1R)
04150 mTOR signaling pathway
100077556 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
100077556 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100077556 (IGF1R)
04140 Autophagy - animal
100077556 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
100077556 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100077556 (IGF1R)
04520 Adherens junction
100077556 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
100077556 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100077556 (IGF1R)
04914 Progesterone-mediated oocyte maturation
100077556 (IGF1R)
09156 Nervous system
04730 Long-term depression
100077556 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
100077556 (IGF1R)
04213 Longevity regulating pathway - multiple species
100077556 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100077556 (IGF1R)
05202 Transcriptional misregulation in cancer
100077556 (IGF1R)
05205 Proteoglycans in cancer
100077556 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100077556 (IGF1R)
05214 Glioma
100077556 (IGF1R)
05218 Melanoma
100077556 (IGF1R)
05215 Prostate cancer
100077556 (IGF1R)
05224 Breast cancer
100077556 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100077556 (IGF1R)
01522 Endocrine resistance
100077556 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oaa01001
]
100077556 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
oaa04090
]
100077556 (IGF1R)
Enzymes [BR:
oaa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100077556 (IGF1R)
Protein kinases [BR:
oaa01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
100077556 (IGF1R)
CD molecules [BR:
oaa04090
]
Proteins
100077556 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100077556
NCBI-ProteinID:
XP_028922481
Ensembl:
ENSOANG00000000134
UniProt:
A0A6I8PAW1
LinkDB
All DBs
Position
5:complement(28758852..29081107)
Genome browser
AA seq
1364 aa
AA seq
DB search
MKSGAGRGSLTLLWGVLFATLCLWPTNGEICGPSIDIRNDIHELKRLENCTVIEGYLQIL
LISKAEDYRNFRFPKLTVITDYLLLFRVAGLESLSDLFPNLTVIRGRNLFYNYALVIFEM
TNLKEIGLYNLRNITRGAIRIEKNSDLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLC
PGTMEENPTCEKTTINNEYNFRCWTTNHCQKMCPSVCGKRACTDQNECCHPECLGSCSAP
DNSTACVACRHYYYEGTCVPTCPPNTYKFEGWRCVNRDFCSKVPGPDINEFEKFVIHNDE
CMQECPSGFIRNGSQSMFCSPCEGPCPKICEEEKKTKTIDSVTSAQMLQGCTVFKGNLLI
NIRRGNNIASELENFMGLIETVTGYVKIRHSHALVSLSFLKSLRYILGEEQLEGNYSFYV
LDNQNLQQLWDWNHRNLTIKEGKMYFAFNPKLCVSEIYRMEEVSGTKGRQTKGDINTRNN
GERASCESDILHFISNTTMKNRIKLTWQRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQD
ACGSNSWNMVDVDLPPNKELKPGILLQGLKPWTQYAIYVKAVTLTMAENDHIRGAKSEIV
YIRTNASVPSIPLDVISASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRHNY
CSKDKIPMRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVF
ENFLHNSIFVPRPPERKRRDVFQIANATLPSRNRNATAVDHFTNVSDTEENESEYPFYES
KVDNRERTLISHLRPFTLYRIDIHSCNHEAESLGCSASNFVFARTMPAEGADNIPGPVTW
EGRKEDNTIYLKWMEPENPNGLILMYEIKYGQHMEDQRECISRQEYRKYGGARLTRLAPG
NYSARVQATSLSGNGSWTEPVSFYVQAKAPDYENFLHLMIALPIAVLLIVGGLLIMLYVF
NKKRNSDRLGNGVLYASVNPEYFSAADVYVPDEWEVPREKITMCRELGQGSFGMVYEGIA
KGVVKDEPETRVAIKTVNESASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVI
MELMTRGDLKSYLRSLRPDTENNPGQAPPTLKKMIQMAGEIADGMAYLNANKFVHRDLAA
RNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSF
GVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQYNPKMRPS
FLEIIGSIKDELDPAFKEVSFFYSEENKPPDTEELDLETENMESIPLDPSSTLQPSEKHS
GHKAENGPGVVVLRASFDERQPYAHMNGGRKNERALPLPQSSAC
NT seq
4095 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggtgccggaagagggtccctgaccttactttggggggttctttttgccaca
ctttgcctttggccaacaaatggagaaatctgtgggccgagcattgatattcgcaatgac
atccatgagctgaagcgcctggaaaactgcacagtgattgagggctacctccaaattctg
ctcatctccaaagcagaagattaccgcaacttccgttttccaaagctcacggttatcacc
gactacttgctgctttttcgcgtggcgggtttggagagcctcagtgacctcttccccaac
ctcacagtcattcgggggagaaacctcttctacaactatgctctggtgatctttgagatg
actaacctcaaggagatcggattgtacaacctgagaaacatcacccggggggccattcgg
atcgagaaaaactcagacctctgttatctctccaccgtggactggtcattgatactggat
gctgtgtctaacaactacatagttgggaataagcctccaaaggagtgtggggacttatgt
ccagggaccatggaggaaaatccaacatgtgagaagaccaccattaacaacgagtataat
ttccgctgctggaccacaaaccactgccagaaaatgtgtcctagtgtgtgtgggaagcga
gcctgcacggatcagaatgagtgctgccatcctgaatgtttggggagctgcagtgcacca
gacaacagcaccgcctgtgtggcatgtcgtcattactactacgagggaacctgtgtgccc
acctgccctccaaatacctataagtttgagggctggcgctgcgtcaacagagacttctgc
tccaaagtgcctggtcccgacatcaacgagtttgaaaagtttgtgatccacaatgacgaa
tgcatgcaggagtgtccctctgggttcatacgaaatgggagccaaagcatgttctgcagc
ccatgtgaaggcccatgtcccaaaatctgtgaagaggagaagaaaaccaagaccattgat
tctgtaacatcagcacaaatgctgcaaggatgcaccgtcttcaagggcaatttactcatt
aacattcggaggggcaataatatagcttcagagctggagaattttatgggcctaattgaa
acagtaacaggatatgtgaagattcgacattctcatgccttagtctccctgtctttttta
aagagtctgcgatatatccttggagaggagcaactggaagggaattactctttctacgtc
cttgataaccagaatttgcagcagctctgggactggaaccatcgtaacctgaccatcaaa
gagggaaaaatgtactttgcttttaatcccaagttgtgtgtttctgaaatttatcgaatg
gaggaggtgtcaggaactaaagggcgtcagaccaaaggggacataaatactaggaacaat
ggagaaagagcttcttgtgaaagcgacattttgcatttcatctccaacactacaatgaag
aaccggattaagctaacatggcagcgatatcgtcctcctgattacagagatcttattagc
ttcactgtttactacaaagaagcacctttcaaaaatgtcactgagtatgatggtcaagat
gcatgtggctctaacagctggaatatggtggatgtggaccttccccccaataaggaactc
aagcctggaattctcctccagggactgaaaccttggacacagtatgcaatttatgtcaaa
gcagttaccctcacaatggcagagaatgaccacatccgtggagcaaaaagtgaaattgtc
tatatccgtaccaatgcctcagtgccctctatacccctggatgttatttcagcatccaac
tcatcctctcagctcattgtgaaatggaatcctccttctcttccaaatggtaacctgtcc
tactacatagtaagatggcagcgacagcctcaggatagttacctttaccgacacaattac
tgctccaaagacaaaattcctatgcgaaagtacgctgatggcaccattgatgttgaagaa
gttaccgaaaaccccaaaactgaagtctgtggaggagagaaagggccttgttgtgcttgt
cctaaaactgaagctgagaaacaagcagaaaaggaggaggctgaataccggaaagtcttt
gagaacttcctccacaactccatctttgtaccgagacctccagaacggaagcggagagac
gtctttcagattgcaaacgccactcttcccagtaggaacagaaacgccacagcagtagat
catttcacaaatgtatcagacacggaggagaatgagtcagagtacccgttctatgagagc
aaagtggacaatagagagaggactttgatctcccacctgaggcctttcactttataccgc
atcgacatccatagctgcaaccacgaagctgaaagtctgggctgcagtgcttccaacttt
gtctttgcaagaaccatgcctgcagaaggagcagataacattccagggccagtaacatgg
gaaggcagaaaggaagataataccatttacctgaaatggatggaacccgaaaaccctaat
ggccttattctaatgtatgaaattaaatatggacagcatatggaggaccagcgggaatgt
atttccagacaagaatatcgaaaatatggaggggccaggcttacccgattagcccctgga
aactattctgcccgtgttcaagccacctctctttctggaaatggatcttggacagaacca
gtgtccttctatgtgcaggccaaagcaccagattatgaaaatttcctccatttgatgatt
gctctccccattgcagtattgctgattgttggagggttgcttataatgctatatgttttt
aacaaaaaaagaaacagtgacagattagggaatggtgtattgtatgcatctgtaaatcca
gagtacttcagtgctgctgatgtgtacgttccagatgagtgggaagtccctcgagagaag
atcaccatgtgtcgagaactaggacagggttcatttgggatggtgtatgaaggaattgct
aagggtgtggtgaaggatgaacctgaaactagagtggccatcaaaacagtcaacgagtct
gccagcatgagggaaagaattgaatttctcaatgaggcttcggtgatgaaggagttcaat
tgtcaccatgtggtacggttgcttggagttgtgtcccaaggtcaacccacattggttatt
atggaattgatgacacgtggagatctcaaaagttatctcagatctctgaggccggatact
gagaataatccaggccaggcccctccaactttaaagaagatgattcagatggctggagag
attgccgatggtatggcttacctcaatgccaataagtttgtccaccgagaccttgccgca
aggaattgcatggtggctgaagatttcactgtcaaaattggagattttggcatgacaaga
gacatctatgagacagattactaccgaaagggaggtaaaggcttgctgcccgtccgctgg
atgtcccctgaatcccttaaggatggagtcttcacaacacactccgacgtctggtcgttt
ggagttgtcctatgggagattgcgacactagcagagcagccatatcagggcatgtctaat
gaacaagttcttcgcttcgtaatggagggcggccttctggagaaaccagacaattgcccc
gatatgttgtttgaattgatgcgcatgtgctggcagtacaaccccaaaatgcgtccttct
ttcctggagatcattggcagcatcaaagatgagctggatccagccttcaaggaggtatcc
ttcttctatagtgaagagaacaagcctccagacacagaagagcttgatctggagactgag
aacatggagagcattcccttagacccctcctccacccttcagccctccgagaaacactca
ggacacaaagccgagaatgggcccggggtggtggtcctccgggccagttttgatgagagg
cagccctacgcgcacatgaatggaggacgcaaaaacgaaagggccttacctttgccccag
tcttcggcctgctga
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