KEGG   Ornithorhynchus anatinus (platypus): 100077964
Entry
100077964         CDS       T01045                                 
Symbol
DNMT3A
Name
(RefSeq) DNA (cytosine-5)-methyltransferase 3A isoform X1
  KO
K17398  DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa00270  Cysteine and methionine metabolism
oaa01100  Metabolic pathways
oaa04148  Efferocytosis
oaa05206  MicroRNAs in cancer
Module
oaa_M00035  Methionine degradation
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    100077964 (DNMT3A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100077964 (DNMT3A)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    100077964 (DNMT3A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:oaa03000]
    100077964 (DNMT3A)
   03032 DNA replication proteins [BR:oaa03032]
    100077964 (DNMT3A)
   03036 Chromosome and associated proteins [BR:oaa03036]
    100077964 (DNMT3A)
Enzymes [BR:oaa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     100077964 (DNMT3A)
Transcription factors [BR:oaa03000]
 Eukaryotic type
  Zinc finger
   Cys4 GATA-factors
    100077964 (DNMT3A)
DNA replication proteins [BR:oaa03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    100077964 (DNMT3A)
Chromosome and associated proteins [BR:oaa03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    100077964 (DNMT3A)
SSDB
Motif
Pfam: DNM3A_N ADD_DNMT3 DNMT3_ADD_GATA1-like DNA_methylase PWWP
Other DBs
NCBI-GeneID: 100077964
NCBI-ProteinID: XP_028927596
Ensembl: ENSOANG00000015836
LinkDB
Position
9:41745691..41847623
AA seq 954 aa
MPSSGAIDSSSSILERDEDRKEEEELEESRGREERQEPGTPMRKVGRPGRKRKHPLVESS
DIPKDLTPASKCTPLAPVPVELLPNGDVEKLAGARLEEGSPAGRKGGPRAESEAEMESPT
ETENARALENGCCNPKDGHETSVDEGKEEKEEANFDSLKMEGSRGRLRGGLGWESSLRQR
PMQRLTFQAGDPYYISKRKRDEWLARWKREQEEAVGKQQSEMRKEEERFSCRQGHSHSCP
APLSRTEISRAEKKAKVIAVMNVVEESPGAGEPQKEEEASPPTVQQPTDPASPTVATTPE
PVVVDAGDKNATKAADDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAE
GTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKL
FPTCPENDESDTAKAVEVQNKQMIEWALGGFQPSGPKGLEPPEEERNPYKEVYTEMWVEP
EAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVT
LEHPLFIGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECV
DLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRRDDWPSRLQMFFANNHDQEFDPPKVY
PPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMY
VGDVRNVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHEARP
KEGDERPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNR
LVRAWPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDI
LWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV
NT seq 2865 nt   +upstreamnt  +downstreamnt
atgccctccagtggtgccatcgatagcagcagctccattctggagagggacgaggaccgc
aaggaggaagaggagctggaggagtcccgtggcagggaagagcgacaggagcccggcaca
cccatgaggaaggtggggcggcctggaaggaaacgcaagcatccgttggtggaaagcagc
gacatcccgaaggatctcaccccagcctccaagtgcactcccctggctccggtccccgtg
gagctgctgcccaacggggatgtggagaaactggctggtgcccggcttgaagagggcagc
cccgctgggcgcaagggtggaccccgggctgagagtgaggcagagatggagagtccgacc
gagaccgagaatgcccgagccctagagaacggctgctgcaaccccaaggatgggcatgag
acctctgtggatgaaggcaaagaagagaaggaggaggctaactttgactccctgaaaatg
gaggggtcccggggccgcttgcgagggggcctgggctgggagtcaagcctgcgccagcga
cccatgcagagactcaccttccaggcaggtgatccctactacatcagcaagcgcaagcgg
gatgaatggctagcacgctggaagcgggagcaggaagaagcagttggaaagcagcagagc
gagatgagaaaggaggaggaaagattttcatgcagacagggacactctcactcctgcccg
gcacccctctccaggactgagatctctagggctgagaagaaagccaaggtgatcgcggtg
atgaatgtggtagaagaaagcccaggagcgggggagccacaaaaggaagaggaggctagc
ccacccaccgtacagcagcccactgaccctgcttcgcccacggtggccaccacccctgag
cccgtggtggttgacgccggcgacaaaaatgccaccaaggcagccgacgatgagcctgag
tatgaggatggccggggctttggcatcggtgagctggtgtgggggaaactgcgaggcttc
tcctggtggccgggccgcatcgtatcctggtggatgactggccggagtcgagcggccgaa
ggcacccgctgggttatgtggttcggagatgggaagttctcagtggtgtgcgtggagaag
ctgatgcctctgagttcgttctgcagtgccttccaccaggccacatacaacaagcagccc
atgtacaggaaagccatctatgaggtccttcaggtggcaagcagccgggcaggaaagctg
ttcccaacctgccctgaaaatgacgagagtgacacagccaaggcggtggaagtacagaac
aagcagatgatcgagtgggccctgggtggcttccaaccctcgggccccaagggcctggaa
ccaccggaagaggagcgaaacccctacaaagaagtttacacagagatgtgggtagaacct
gaagccgctgcctacgccccacctccacccgccaaaaagccccgcaaaagcacagctgag
aagcccaaggtcaaggagatcattgacgaacgcacacgagaacgactggtgtacgaggta
cgacagaaatgcagaaacattgaagacatatgcatctcctgtgggagcctcaacgtcacc
ctggaacaccccctcttcatcggaggaatgtgccaaaactgcaagaactgctttctggag
tgtgcgtatcagtacgatgatgacggctaccagtcctactgcaccatttgttgtggcggg
cgagaggtccttatgtgcggcaacaacaactgctgcaggtgcttctgtgtggaatgcgtg
gatctcctggtggggccgggtgccgcccaggccgctatcaaggaggatccctggaactgc
tacatgtgtgggcacaaggggacctatgggctactgcggcggcgggatgactggccctcc
cgcctccagatgttcttcgccaacaaccacgaccaagaatttgacccaccaaaggtttac
cctccagtcccggctgagaagaggaagcctatccgagtgttgtctctctttgatggaatt
gctacagggcttctggtgctgaaggacttggggatccaggtggaccgttacattgcctca
gaagtgtgcgaggactccatcacagtgggcatggtgcggcaccagggcaagatcatgtat
gtgggcgacgtccgcaacgtcacgcagaagcacatacaggagtggggcccttttgacctg
gtaatcggaggcagtccctgcaatgacctctctatcgtcaaccctgctcgcaagggcctc
tatgagggcaccgggcggctcttctttgagttctatcggctcctgcatgaagcacgaccc
aaggagggggatgagcgccccttcttctggctttttgaaaatgtggtggccatgggtgtc
agtgacaagagggacatctcacgcttcctagagtccaaccctgtgatgatcgatgccaaa
gaagtgtctgcagctcacagggcccggtacttctggggtaacctacccggtatgaacagg
ttggtgagagcatggcccttggcatcaacagtgaatgataagctggaattacaggaatgt
ctggagcacggcaggatagctaagttcagcaaagtgaggaccatcaccactcggtcaaac
tccatcaaacaaggcaaagaccagcatttccctgtcttcatgaatgagaaagaggacatc
ttgtggtgcactgaaatggaaagggtctttggcttcccagtccattacactgacgtctcc
aacatgagccgtttggcgaggcagagactcctgggtcggtcgtggagcgtgcctgtgatc
cgtcacctcttcgcccccttgaaggagtattttgcctgtgtgtaa

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