Ornithorhynchus anatinus (platypus): 100078235
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Entry
100078235 CDS
T01045
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa00140
Steroid hormone biosynthesis
oaa01100
Metabolic pathways
oaa05215
Prostate cancer
Module
oaa_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100078235 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
100078235 (SRD5A2)
Enzymes [BR:
oaa01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
100078235 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
Motif
Other DBs
NCBI-GeneID:
100078235
NCBI-ProteinID:
XP_028905803
Ensembl:
ENSOANG00000003946
UniProt:
F6U0E0
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Position
X1:14025356..14077519
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AA seq
258 aa
AA seq
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MAEGCHASPVSAGSGAMALLGAWAALGGRPAPYGKGTERLLPGAARLPARAAWCLQELPS
LLLPAALAALAARRPAPDAHRPHRPLLLALFCAHYFHRALIYPFFTKGRPFPVRVTISAA
LFCTINGLLQGYYLTYCAEYPDDWYTDIRFVAGIVMFFLGMGVNIHSDHLLRQLRKPGEI
TYKIPQGGMFAYVSGANFLGEIVEWMGFALATWSLPALAFAFFSLCFLGNRAYHHHRFYL
EVFPNYPKSRKALIPFIF
NT seq
777 nt
NT seq
+upstream
nt +downstream
nt
atggccgaagggtgccacgcgtctccggtgtctgcgggcagcggggcgatggctctgctg
ggggcgtgggcggcgctggggggtcgccccgcgccctacggcaagggcacggagcggctg
ctgcccggggccgcccgcctgcccgcccgggccgcctggtgcctgcaggagctgccctcc
ctcctgctgcccgcggccctggccgccctggccgcccgacgcccggcgcccgacgcccac
cgccctcaccggcccctgctcctcgccctcttctgcgcccactacttccacagggcactc
atttacccgttcttcaccaagggaagacctttcccagttagggtgactatatcggccgct
ctcttctgtactatcaacggcctccttcaagggtactacctgacatactgtgccgaatac
cccgatgattggtacactgacatccgattcgtggcaggtatcgtgatgttttttttggga
atgggcgtcaatattcacagtgaccatttactgcgtcaactcagaaagcctggagaaatc
acctataagattcctcaagggggaatgttcgcttatgtatctggagccaactttttgggg
gagattgtggaatggatgggctttgcccttgctacctggtccctccctgctttggcgttc
gcatttttttccctgtgcttccttgggaacagagcttaccatcatcacaggttctatctc
gaggtctttccaaactacccgaaatcccggaaagccctgattcctttcatcttttaa
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