KEGG   Ornithorhynchus anatinus (platypus): 100078394
Entry
100078394         CDS       T01045                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa04010  MAPK signaling pathway
oaa04015  Rap1 signaling pathway
oaa04218  Cellular senescence
oaa04380  Osteoclast differentiation
oaa04620  Toll-like receptor signaling pathway
oaa04664  Fc epsilon RI signaling pathway
oaa04668  TNF signaling pathway
oaa04750  Inflammatory mediator regulation of TRP channels
oaa04912  GnRH signaling pathway
oaa04935  Growth hormone synthesis, secretion and action
oaa04936  Alcoholic liver disease
oaa05014  Amyotrophic lateral sclerosis
oaa05022  Pathways of neurodegeneration - multiple diseases
oaa05132  Salmonella infection
oaa05135  Yersinia infection
oaa05145  Toxoplasmosis
oaa05161  Hepatitis B
oaa05163  Human cytomegalovirus infection
oaa05167  Kaposi sarcoma-associated herpesvirus infection
oaa05169  Epstein-Barr virus infection
oaa05170  Human immunodeficiency virus 1 infection
oaa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oaa05417  Lipid and atherosclerosis
oaa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100078394 (MAP2K6)
   04015 Rap1 signaling pathway
    100078394 (MAP2K6)
   04668 TNF signaling pathway
    100078394 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    100078394 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100078394 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    100078394 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100078394 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    100078394 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100078394 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100078394 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100078394 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100078394 (MAP2K6)
   05161 Hepatitis B
    100078394 (MAP2K6)
   05163 Human cytomegalovirus infection
    100078394 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100078394 (MAP2K6)
   05169 Epstein-Barr virus infection
    100078394 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100078394 (MAP2K6)
   05135 Yersinia infection
    100078394 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100078394 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100078394 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    100078394 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100078394 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    100078394 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100078394 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oaa01001]
    100078394 (MAP2K6)
Enzymes [BR:oaa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100078394 (MAP2K6)
Protein kinases [BR:oaa01001]
 Serine/threonine kinases: STE group
  STE7 family
   100078394 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 100078394
NCBI-ProteinID: XP_028935533
Ensembl: ENSOANG00000008075
UniProt: A0A6I8PG96
LinkDB
Position
15:5665346..5776636
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGDKNFEVKADDLEPIAELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCHFTVTFYGALF
REGDVWICMELMDTSLDKFYKHVIDKGLTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPVGKFSADFVDFTSQCLKKNSK
ERPTYPELMQHLFFTLHESKETDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaacccagggctgaaaattcccaaagaagcattt
gagcaacctcagaccagctccacgccaccgcgggatttggactccaaagcctgcatctca
attggggataagaatttcgaagtgaaagctgacgacctggagcctatagcagaactggga
cgaggtgcgtacggggtagtggagaagatgcgacacgtgcctagcgggcagatcatggcg
gtgaagcgaatccgggcgacagtgaacagtcaggagcagaagaggctcctgatggatctg
gacatctccatgaggacggtggattgtcatttcacggtcaccttctatggtgcgctcttc
cgggagggcgatgtgtggatctgcatggaacttatggacacgtccctggataaattctat
aagcacgtcattgacaaaggtctgacaattcccgaggacatcttgggaaaaatcgcagtc
tcgatcgtaaaggcactagaacacctacacagtaagctctctgtcattcaccgagatgtc
aagccgtcgaacgtgttgatcaataccctgggccaagtgaagatgtgtgactttggaatc
agcggttacctcgtagactctgttgctaaaactatggacgcaggatgcaagccttacatg
gcccccgagagaataaacccggagctgaaccagaaaggatacagcgtgaaatccgacatc
tggagtctgggcataacaatgatcgaactggccatcctgcggttcccctacgattcctgg
ggcaccccgttccagcagctcaaacaggtggtggaagagccgtcaccccagcttcccgtg
ggcaagttctcagcagacttcgttgactttacctcacagtgcttgaagaagaattctaaa
gagcggccaacatacccagaactcatgcaacatctttttttcactctacatgaatccaaa
gagacagatgtggcatcttttgtaaaactgattcttggagactaa

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