Ornithorhynchus anatinus (platypus): 100078541
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Entry
100078541 CDS
T01045
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa00061
Fatty acid biosynthesis
oaa00620
Pyruvate metabolism
oaa00640
Propanoate metabolism
oaa01100
Metabolic pathways
oaa01212
Fatty acid metabolism
oaa04152
AMPK signaling pathway
oaa04910
Insulin signaling pathway
oaa04922
Glucagon signaling pathway
oaa04936
Alcoholic liver disease
Module
oaa_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100078541 (ACACA)
00640 Propanoate metabolism
100078541 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100078541 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100078541 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100078541 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100078541 (ACACA)
04922 Glucagon signaling pathway
100078541 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100078541 (ACACA)
Enzymes [BR:
oaa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100078541 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100078541 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100078541 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
MetallophosN
Motif
Other DBs
NCBI-GeneID:
100078541
NCBI-ProteinID:
XP_028938506
Ensembl:
ENSOANG00000011506
UniProt:
A0A6I8NH07
LinkDB
All DBs
Position
17:complement(14407959..14666942)
Genome browser
AA seq
2349 aa
AA seq
DB search
MDEPSTLTKPLDLNQHSRFIIGSVSEDNSEDEISSLVKLDLLEEKEGSLSPASVSSDTLS
DLGLSGLQDGPGLAVHMRPSMSGLHLVKQGRDRKKVDLQRDFTVASPAEFVTRFGGNKVI
EKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPV
PGGTNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMW
ALGDKIASSIVAQTAGIPTLPWSGSGLCVDWQENDFQKPILNVPQEVYEKGYVKDVDDGM
LAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHL
EVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATSVIFERMEQCAVKLAKMVGYV
SAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRM
MYGVSPWGDVPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVW
GYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLL
ETESFQQNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSVSNFLHSLERG
QVLPAHTLLNTADVELIYEGAKYVLKVTRQSPNSYVVIMNGSCMEVDVHRLSDGGLLLSY
DGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVLRSPSAGKLIQYIIEDGGHVFAGQC
YAEIEVMKMVMTLTSVESGCIHYVKRPGAALDPGCVIAKLQLDNPTKVQQAELHTGILPR
IQSTALRGEKLHRVFHYVLDNLVNVMSGYCLPDPFFSNRVKDWVERLMKTLRDPSLPLLE
LQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSER
EVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQHGHYDKCVFALREENK
SDMNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVA
LRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFF
YHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLN
RMSFSSNLNHYGMAHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCD
SPPQSPTFPEAGHTSLYDEEKAARDEPIHILNVAIKTDCDIEDDGLAAIFREFTQCKKAV
LIEHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALA
FQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGIEVTDYRFFVRAIIRHSDLVTKEAS
FEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMR
YGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMF
QAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQTLGTTYIYDIPEMFRQSLLKLWESMAA
QAFLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDII
VIGNDITYRIGSFGPQEDILFLRASELARAQGIPRIYVAANSGARIGLAEEIRHMFHVAW
VDPADPYKGYKYLYLTPQDYKKVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLR
GSGMIAGESSLAYDKIITISLVSCRAIGIGAYLVRLAQRTIQVENSHLILTGAAALNKVL
GREVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVLTILHWLSYMPKNVYSPVPMLNSKDP
IDRIIEFVPTKAPYDPRWMLAGRPHPGQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARL
GGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGL
PLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVLVYIPPQAELRGGSWVVIDP
TINPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIHLAERLGTPELSP
AERKELEAKLKEREEFLTPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWR
LRRLLLEDLVKKKIHDANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQL
NEEEGARSVVDENIKYISRDYILKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRIL
STMDSPPST
NT seq
7050 nt
NT seq
+upstream
nt +downstream
nt
atggacgaaccatctactttgaccaagcccctggacctgaatcagcactctcgcttcata
attggctccgtgtccgaagataactcggaggacgagatcagctccttggtgaagctcgac
ttgctggaagaaaaggaggggtccctgtcgccggcttccgtctcctcggacaccctgtcc
gacctggggctctccggcctccaggatggccccggtctggctgtgcacatgaggcccagc
atgtctggcctacacctggtaaaacaaggccgcgatcgaaagaaagtagacctgcagcga
gatttcaccgtggcttctccagcagaatttgtgactcgttttggaggaaataaagttatc
gagaaggttctcatcgccaacaatggcatcgctgccgtgaaatgcatgcggtctatccgc
cggtggtcttatgagatgtttagaaatgagcgggccattagatttgtggtcatggtcaca
cccgaagatctgaaagccaacgcagagtacattaagatggcagaccactatgtgccggtg
ccagggggcacgaacaacaacaactatgcaaacgtggaacttattctcgatatcgcgaaa
aggattccggtgcaggcagtgtgggctggctggggtcacgcttccgagaatcccaagctt
ccagaactcctccttaaaaacggcattgcctttatgggtcctccaagccaagccatgtgg
gctctgggtgataaaatcgcttcctccattgtggcccagactgcaggcatccccactctt
ccctggagtggcagcggtctttgtgtcgactggcaggagaacgattttcagaaacccatc
ttgaacgttccccaggaggtgtatgaaaagggttatgtgaaggatgtggatgatgggatg
ctggcagctgaggaagttggatacccagtgatgatcaaggcttcagaaggaggaggggga
aaaggaatcagaaaagtcaacaatgcagatgacttccctaacctcttcagacaggttcaa
gctgaagtgcccggctcgcccatctttgtgatgagactggccaaacagtcccgtcatttg
gaagtgcagattctggccgatcagtacggcaacgccatctccctgttcggccgcgactgc
tctgtgcagcgcaggcaccagaagatcatcgaagaggcgcccgccaccatcgcgacctct
gtcattttcgagcgcatggagcagtgtgccgtgaagctggccaagatggttggctacgtg
agcgcgggcacggtggagtacctctacagccaagacggcagcttttacttcctggaattg
aatccccggctccaggtggaacacccctgcacggagatggtagccgacgtcaatctgcct
gccgcccagctccagatcgccatgggaattcctctgtaccgaatcaaggacatacgcatg
atgtacggggtgtccccctggggagacgtccccattgattttgagaactccgcccacgtc
ccgtgcccccggggccacgtcatcgccgcgcggatcaccagtgagaatccagacgagggt
tttaaacccagttcaggaacagtccaggaactgaacttccgcagtaataagaacgtgtgg
ggatattttagcgtggcggccgccgggggacttcacgagtttgcagattctcagtttggc
cactgcttctcctggggagagaacagagaggaagcaatttcaaacatggtggtggccctg
aaggagctgtccatccgaggggacttccgaaccacggtcgagtacctcatcaaactgttg
gagacggagagcttccagcagaacagaatcgataccggctggttggacaggctgatagcc
gagaaggtccaggcggagcggcccgacaccatgttgggggtagtgtgcggagccctgcac
gtagccgacgtgagcctgcggaacagcgtctccaacttcctgcattccctggagaggggc
caagtactgcccgctcatacgcttctgaacacagcagacgtagagctgatctatgaaggg
gccaagtatgtattgaaggtgacccggcagtcccccaactcgtacgtggtgatcatgaac
ggctcctgcatggaagtggatgttcatcgactgagcgacggcgggctgctcctgtcctac
gacggcagcagctacaccacctacatgaaagaagaagtggacaggtaccgcatcacgatc
ggcaacaagacgtgtgtgtttgagaaggagaacgacccttctgtgctgcgctccccttcg
gctgggaagttgatccagtacatcatagaagacgggggtcatgtctttgcgggccagtgc
tacgccgagatcgaggtgatgaagatggtgatgactctgacatctgtggagtctggctgc
atccattatgtcaagcggcccggggccgccctggaccctggctgcgtgattgccaaactg
cagctggacaaccctaccaaagttcagcaggccgaactgcacaccgggatcttgccacgg
atccagagtacggcactgcgaggcgagaaactccaccgagtcttccattacgtcttggac
aacctagtcaatgtaatgagcggctactgtctcccggaccccttcttcagcaacagggtg
aaagattgggttgaacgactgatgaagactcttcgagacccttccttgcctctcttggag
ctgcaggacatcatgaccagtgtctccggacgcatccctccaaatgtggagaagtccatc
aaaaaggagatggcccagtatgctagcaacattacgtcggtcctctgccagtttcccagc
cagcagattgccaacatcttggacagccacgcggccactctgaaccgcaagtctgagaga
gaggttttcttcatgaacacacagagcatcgtgcaactcgtacagaggtaccggagtggc
attcggggccacatgaaggccgtggtaatggacctgcttcggcagtacctgcgagtggag
actcagttccagcacggtcactatgacaagtgtgtgtttgcccttcgggaggagaacaag
agtgacatgaacactgtgctgaactacatcttctcccacgctcaggtcaccaagaagaac
ctgctggtcacgatgctcattgaccagttgtgcggccgggatcccaccctgaccgacgaa
ctgctgaacatcctcaccgagctgacccagctcagcaagaccaccaatgccaaagtggcc
ctgcgagcccgacaggttctaatagcctcccatctgccatcctacgaactgcgtcataac
caagtggagtccatctttctgtccgcgattgacatgtacggacaccagttctgcatcgag
aacctgcagaaactcatcttgtctgaaacatccatttttgatgtcctcccaaatttcttc
taccacagcaaccaggtggtgagaatggcagctctggaggtatatgtcagaagggcctat
atcgcctatgagctcaacagcgtacagcatcgtcagctgaaggacaacacgtgcgtggtg
gaatttcagttcatgcttcctacatcccatccaaatagagggaacatccccacgctaaac
agaatgtccttctcctccaacctcaaccactatggcatggctcacgtggccagcgtcagc
gacgtgctgctggacaactccttcaccccgccgtgccagaggatgggggggatggtctcc
ttccgaaccttcgaagacttcgtcaggatctttgatgaagtgatgggctgtttctgtgac
tcccctcctcaaagccccacgttccccgaggcgggccacacctccctgtatgatgaagaa
aaggctgccagagatgagccaatccacatcctgaatgtggccatcaagacggactgtgac
atcgaggacgacgggctggcggccatattcagagagtttacccagtgcaagaaagccgtc
ctcatagaacatgggatccgtcgacttactttcctggttgcacaaaaggatttcagaaag
caggtcaactatgaggtggatcaaagatttcatagagagttccccaaatttttcacgttc
cgagcaagagataagtttgaggaggatcgcatctatcgacacttagagcccgcactggct
tttcagctggagctaaaccgcatgcgaaacttcgacctcactgccatcccgtgcgccaat
cataagatgcacttgtacctgggggcagccaaggtggaagtgggtatagaagttaccgac
tacaggttcttcgtgagggcgatcatcaggcattctgacctggtcaccaaggaagcctcc
tttgagtatctgcagaacgaaggagagcgcctgctcctggaagccatggatgagctggag
gttgctttcaacaacacaaacgtccgcaccgactgcaaccacatcttcctcaactttgtg
cccaccgtcatcatggacccctccaagatcgaggagtcggtgcggagtatggtgatgcgc
tacgggagtcggctctggaaactccgagtccttcaggcggaactgaaaatcaacattcgc
ctgactccgaccggaaaagcgattcccatccgcctcttcctaaccaatgagtccggctat
tacttggacattagcctttacaaggaagtgaccgactccaggacagcacagattatgttc
caggcctacggagacaaacagggaccactgcatggcatgctgatcaatactccctacgtg
accaaggacctactgcagtctaagcggtttcaggcccagaccttaggaacgacctacatc
tatgacattccggagatgtttcgacagtcgctgcttaaactctgggagtccatggccgct
caggcattcctgccctcaccgcccctaccttccgacatactgacgtataccgaactggtg
ttggacgatcaaggtcagctagtacatatgaacaggcttccaggaggaaatgagattggc
atggtagcctggaaaatgacgcttaagagccccgagtacccagagggcagagacatcatt
gttatcggcaacgacatcacttaccgaatcggttcctttgggccgcaggaggacatcttg
tttctgagggcctctgagcttgccagagcgcaaggcatcccccgcatttacgtggcggcg
aatagcggagcgagaataggattagccgaagagatccgccacatgtttcacgtggcttgg
gtggatcctgccgatccatacaagggatacaagtacttgtatctgactcctcaagattac
aagaaagtcagtgccctgaactcggttcactgtgagcatgtggaggatgaaggagaatcc
aggtacaagataacggatattatcgggaaggaagaaggccttggagcagagaacctgaga
ggctctgggatgattgctggagaatcctcattggcctacgacaagataatcaccatcagc
ttggtttcatgtcgggccattgggattggggcgtatcttgtccgattagcccagagaact
atccaggttgagaactcacatttgattttgaccggagctgcagcccttaataaagtgctt
ggacgggaggtgtatacctccaacaatcagcttgggggcatccagattatgcacaacaat
ggggtgacgcatagcactgtgtgcgatgactttgaaggggttctgaccatcctccactgg
ctatcctacatgccgaagaacgtatacagtccagttcctatgctcaactccaaggatcct
atagaccgaatcattgaatttgtccctaccaaagccccatatgatccccgctggatgctg
gcaggacggccacacccaggccagaaaggccagtggctgagtggattttttgactacggc
tccttctcggagattatgcaaccttgggcccagaccgtagtggttggtcgagccaggctg
ggaggaatacctgtaggagtggttgccgtagaaaccagaacggtggagctaagtatccca
gctgatcctgcaaacctggattctgaggccaagatcatccaacaggctggccaggtttgg
ttcccagactcggccttcaagacgtatcaagctatcaaggacttcaaccgggaggggctg
cctctgatggtgtttgccaactggagaggtttttctggtggaatgaaagacatgtacgac
caggtgctgaagttcggcgcctacatcgtggacggcttacgcgagtgctctcagccggtc
ctggtttacatccctcctcaggccgagctccggggagggtcctgggtcgtcatcgatccc
accatcaacccccggcacatggagatgtacgcggaccgggaaagcaggggatcggtcctg
gaaccagaggggacggtggaaatcaaattccgcaaaaaggatttggtgaagaccatgcgc
cgagtggacccagtctacatccacctggcggagcgtctaggcaccccagagctcagcccc
gccgagcggaaggagctggaagccaagctgaaggagcgggaggaattcctcactcccatc
taccaccaggtcgccgtgcagtttgccgacttgcatgacacgccgggccggatgcaggag
aagggggtcattaacgatatcctggactggaaaacctcccggaccttcttctactggaga
ctgaggcgcctcttgctggaggacttggtgaagaagaagatccacgacgccaaccccgag
ttgacggacggacagatccaagccatgttgaggcgctggtttgtggaagtcgagggaacg
gtaaaggcctacgtgtgggacaacaacaaggatctggtggagtggctggagaagcagcta
aatgaagaggagggcgcccgctcggtggtcgacgaaaacatcaagtacatctccagagat
tacatactcaagcagatccgtagcttggtgcaggccaatccggaggtggccatggattcc
atcgtccacatgacccaacacatctcgccgactcaacgcgcggaagtggtgcggatcctc
tcgacgatggattcccctccttcgacgtag
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integrated database retrieval system
