KEGG   Ornithorhynchus anatinus (platypus): 100078645
Entry
100078645         CDS       T01045                                 
Symbol
HPGDS
Name
(RefSeq) hematopoietic prostaglandin D synthase isoform X1
  KO
K04097  prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa00480  Glutathione metabolism
oaa00590  Arachidonic acid metabolism
oaa00980  Metabolism of xenobiotics by cytochrome P450
oaa00982  Drug metabolism - cytochrome P450
oaa01100  Metabolic pathways
oaa05204  Chemical carcinogenesis - DNA adducts
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    100078645 (HPGDS)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    100078645 (HPGDS)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100078645 (HPGDS)
   00982 Drug metabolism - cytochrome P450
    100078645 (HPGDS)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    100078645 (HPGDS)
Enzymes [BR:oaa01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     100078645 (HPGDS)
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.99  Other intramolecular oxidoreductases
    5.3.99.2  prostaglandin-D synthase
     100078645 (HPGDS)
SSDB
Motif
Pfam: GST_C_3 GST_N GST_N_2 GST_C GST_N_3
Other DBs
NCBI-GeneID: 100078645
NCBI-ProteinID: XP_039769670
Ensembl: ENSOANG00000013762
UniProt: A0A6I8P903
LinkDB
Position
12:29041275..29052025
AA seq 214 aa
MPNLKLVYFNLRGRAEIIRYLFAYMDLKYEDRRIEPADWPGIKSLLPFGKIPILEVDGVT
LHQSLAIARYFAREAGLAGKSELEQCQVDAVVDTLDDFMAAFPWDEKIQDVKLRSTVQEC
RTSSLSKEQAFSKLLADGAPTLLRNLETYLAESEWLVGQSVTWADFYWDICSTTLLALKP
TLLDNFPTLVALRGRVQTIPAIAAWISRRPETRL
NT seq 645 nt   +upstreamnt  +downstreamnt
atgccaaacctcaagctggtctactttaatctgcggggaagagcagaaataatccgttat
ctgtttgcctacatggacctgaaatacgaagaccggagaatagagcctgcggactggccg
ggaatcaaatcactgcttccatttgggaaaattcccattctggaagttgatggagtgacc
cttcaccagagcctggctatagcgcggtactttgccagagaagcaggcttggccgggaag
tcagagctggagcagtgtcaagttgacgccgtcgtggacaccctggatgacttcatggcg
gcttttccctgggacgagaaaattcaagatgtgaaactgaggtcaactgttcaggaatgc
aggacgtcctccttaagcaaggagcaggcattcagcaagctgctcgccgatggggctccg
acgttgctgcggaacctggagacgtacctggcggagagcgaatggctggtcggtcaatcg
gtaacctgggctgatttctactgggacatctgcagtacgacacttctggccttaaaaccc
acgttgttagacaacttccccacgcttgtggccctgagaggccgagtgcaaaccatcccc
gccatcgcggcctggatcagccggcggccagagacgaggctatag

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