Ornithorhynchus anatinus (platypus): 100079095
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Entry
100079095 CDS
T01045
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa00260
Glycine, serine and threonine metabolism
oaa00630
Glyoxylate and dicarboxylate metabolism
oaa00670
One carbon pool by folate
oaa01100
Metabolic pathways
oaa01200
Carbon metabolism
oaa01230
Biosynthesis of amino acids
oaa01240
Biosynthesis of cofactors
oaa01523
Antifolate resistance
oaa04981
Folate transport and metabolism
Module
oaa_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
100079095 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
100079095 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100079095 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100079095 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100079095 (SHMT1)
Enzymes [BR:
oaa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
100079095 (SHMT1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
100079095
NCBI-ProteinID:
XP_007654785
Ensembl:
ENSOANG00000009875
UniProt:
K7EA77
LinkDB
All DBs
Position
2:33732695..33751729
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AA seq
484 aa
AA seq
DB search
MAAPVNGETQNVKLWESHSNMLVQPLKDNDTEVYSIIKKESHRQKVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFVDELELLCQKRALQAYNLDPQSWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPNTGY
IDYDQLEENARLFHPKLIIAGISCYSRNLDYARMRKIADENGAYLMADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFFRKGVRSVDPKTGKETQYNLESLINTAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFKVYQQQVVANCKALSAAMTELGYHVVTGGSDNHLIL
VDLRNKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLENDFKK
VAYFIHRGIELTRMIQSEMAAKATLKEFKERLAGDEKYQSIIKSIREEVEAFASVFPLPG
LPDF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcagccccagtcaatggagagactcagaatgtcaaactctgggaatcccatagtaat
atgcttgtacagcctcttaaagacaatgatacagaggtgtattccatcatcaagaaggag
agtcatcgtcagaaggttggcttggagctgattgcttcagagaactttgccagccgagcc
gtcctggaggccctgggctcctgcttgaacaacaaatactcggaagggtacccagggcag
aggtattatggtggaacagagtttgtggatgagctggagctcctgtgtcagaagagggct
ttgcaggcctataatctggatccacaaagctggggagttaacgtgcagccctattcaggc
tctccagcgaactttgcagtgtacactgccctggtggagccacatgggaggatcatgggt
ctggacctaccagatgggggtcatctgacccacgggttcatgactgacaagaagaaaatc
tcggctacctctatcttctttgagtccatgccttacaaggtgaacccaaacactggctat
attgactacgaccaactggaggaaaatgcccggctcttccacccaaagctgattatcgca
ggaatcagctgttactctcggaacctggactatgcccggatgcgcaagattgctgatgag
aatggggcctacctcatggctgacatggcccacatcagcggcctggttgccgctggagtg
gtgccttccccgtttgaacactgccacgtggtgtctaccacaactcacaagaccttgcga
ggctgccgagcgggcatgatcttcttcaggaaaggagtgcgcagtgtggaccctaaaaca
ggcaaagagacgcagtacaacctggagtcactcatcaacactgcagtttttccgggactt
cagggaggccctcacaatcacgccattgctggagtcgctgtggccctgaagcaagccatg
acccctgaatttaaggtttatcagcagcaggtggttgccaactgcaaggctctatctgca
gccatgactgagctgggctaccatgttgtaacaggtggttctgacaaccatctgatcctc
gtggacctacgcaacaagggcactgacggagggagagctgagaaggtcctggaagcctgc
tctattgcctgtaacaagaacacctgcccaggtgacaaaagtgctttgcggcccagtggt
ctgagactggggactccagcattgacctccagaggcctcctggaaaatgatttcaaaaaa
gtagcttattttatccacagaggaatagaactgactcggatgattcaaagtgagatggcc
gctaaagccactctgaaggagttcaaagagagactggcgggagatgagaagtaccagagc
atcatcaagtccatcagagaggaggtggaggcctttgcttctgtcttcccgttgcccggc
ctgcctgacttttga
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