Ornithorhynchus anatinus (platypus): 100079669
Help
Entry
100079669 CDS
T01045
Symbol
BACE1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100079669 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
oaa01002
]
100079669 (BACE1)
Enzymes [BR:
oaa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
100079669 (BACE1)
Peptidases and inhibitors [BR:
oaa01002
]
Aspartic peptidases
Family A1: pepsin family
100079669 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
100079669
NCBI-ProteinID:
XP_001509790
Ensembl:
ENSOANG00000014353
LinkDB
All DBs
Position
11:54741662..54759064
Genome browser
AA seq
498 aa
AA seq
DB search
MARALPWLLLWAVLPARGAHPGIQVPLKTRQGGSAPGPRLPRAAGEGPGDPGPGGSFVEM
VDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLRRYYRRQLSSTYRD
LRKGVYVPYTQGKWEGELGSDLVAVPHGPNVTVRANIAAITESDKFFINGSNWEGILGLA
YAEIARPDDSLEPFFDSLVKQTSVPNLFSLQLCGAGFSLNETEAPASVGGSMIIGGIDPS
LYVGGLWYTPIRREWYYEVIIVRMEINGQDLKLDCKEYNYDKSIVDSGTTNLRLPKKVFA
AAVKSIKTASSTEKFPDGFWLGEQLVCWQAGTTPWDIFPVISLYLMGEVTNQSFRITILP
QQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSTCHVH
DEFRMAAVEGPFVTPDTEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCL
RCLRRPRDDFADDISLLK
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
atggcccgggcgctgccctggctgctgctctgggcagtgctgcccgcccggggggcccat
ccgggcatccaggtgcccctgaagaccaggcaggggggatcggcccccggcccccggctg
ccccgggcggccggcgagggacccggagaccccgggccggggggcagcttcgtggagatg
gtggacaatctacggggcaagtccgggcagggctactacgtggagatgaccgtggggagt
cccccccagacgctgaacatcctggtggacacgggcagcagtaacttcgccgtgggggcc
gccccccaccccttcctaaggcgctactaccggcgacagctgtccagtacctaccgagac
ctgcggaagggtgtgtacgtgccctacacccagggcaagtgggagggggagctgggcagc
gacctggtggccgtccctcacggccccaacgtcaccgtgcgggccaacatcgccgccatc
accgagtctgacaagttcttcatcaacggctccaactgggagggcatcctggggctggcc
tacgccgagatcgccaggcctgacgacagcctggagcccttctttgactccctggtgaag
cagacgtcagtccccaacctcttctccctgcaactgtgcggcgccggcttctccctcaac
gagaccgaggccccggcttccgtcggtgggagcatgattatcggaggcatcgatccctcc
ctatacgtgggcggcctgtggtacacgcccatccggagggagtggtactacgaggtcatc
atcgtgcgcatggagatcaatgggcaggacctgaagttggactgcaaggagtacaactac
gacaagagcatcgtggacagtggcacgaccaacttgcgtctccccaagaaggtgttcgcg
gctgcggtcaagtccatcaagacggcgtcctcgacggagaagttcccggatggcttctgg
ctcggggagcagctggtgtgctggcaggcgggcacaacgccctgggacattttcccggtc
atttccctctacctgatgggggaggtcaccaaccagtccttccgcatcaccatcctgcca
cagcaatacctgaggccggtggaagacgtggccacatcgcaggatgactgctacaaattt
gccatctcccagtcgtccacgggcaccgtgatgggcgctgtcatcatggagggcttctac
gtcgtcttcgaccgtgcccgcaagcgaatcggctttgccgtcagcacctgccacgtgcac
gacgagttccgaatggcggcggtggagggtcccttcgtgacgccggacacggaggactgc
ggctataacatcccgcagacggacgagtcgacgctgatgaccatcgcctacgtcatggct
gccatctgcgccctcttcatgctgccgctctgcctcatggtttgccagtggcgctgcctc
cgctgcctgcgccgcccgcgggacgacttcgccgacgacatctccctgctcaagtga
DBGET
integrated database retrieval system
