KEGG   Ornithorhynchus anatinus (platypus): 100080392
Entry
100080392         CDS       T01045                                 
Symbol
GNAS
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha isoform X1
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa01522  Endocrine resistance
oaa04015  Rap1 signaling pathway
oaa04020  Calcium signaling pathway
oaa04024  cAMP signaling pathway
oaa04072  Phospholipase D signaling pathway
oaa04081  Hormone signaling
oaa04082  Neuroactive ligand signaling
oaa04261  Adrenergic signaling in cardiomyocytes
oaa04270  Vascular smooth muscle contraction
oaa04540  Gap junction
oaa04611  Platelet activation
oaa04713  Circadian entrainment
oaa04714  Thermogenesis
oaa04724  Glutamatergic synapse
oaa04726  Serotonergic synapse
oaa04728  Dopaminergic synapse
oaa04730  Long-term depression
oaa04750  Inflammatory mediator regulation of TRP channels
oaa04911  Insulin secretion
oaa04912  GnRH signaling pathway
oaa04913  Ovarian steroidogenesis
oaa04915  Estrogen signaling pathway
oaa04916  Melanogenesis
oaa04918  Thyroid hormone synthesis
oaa04921  Oxytocin signaling pathway
oaa04922  Glucagon signaling pathway
oaa04923  Regulation of lipolysis in adipocytes
oaa04924  Renin secretion
oaa04925  Aldosterone synthesis and secretion
oaa04926  Relaxin signaling pathway
oaa04927  Cortisol synthesis and secretion
oaa04928  Parathyroid hormone synthesis, secretion and action
oaa04934  Cushing syndrome
oaa04935  Growth hormone synthesis, secretion and action
oaa04961  Endocrine and other factor-regulated calcium reabsorption
oaa04962  Vasopressin-regulated water reabsorption
oaa04970  Salivary secretion
oaa04971  Gastric acid secretion
oaa04972  Pancreatic secretion
oaa04976  Bile secretion
oaa05012  Parkinson disease
oaa05030  Cocaine addiction
oaa05031  Amphetamine addiction
oaa05032  Morphine addiction
oaa05034  Alcoholism
oaa05142  Chagas disease
oaa05146  Amoebiasis
oaa05163  Human cytomegalovirus infection
oaa05165  Human papillomavirus infection
oaa05200  Pathways in cancer
oaa05207  Chemical carcinogenesis - receptor activation
oaa05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100080392 (GNAS)
   04020 Calcium signaling pathway
    100080392 (GNAS)
   04072 Phospholipase D signaling pathway
    100080392 (GNAS)
   04024 cAMP signaling pathway
    100080392 (GNAS)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    100080392 (GNAS)
   04081 Hormone signaling
    100080392 (GNAS)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100080392 (GNAS)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100080392 (GNAS)
  09152 Endocrine system
   04911 Insulin secretion
    100080392 (GNAS)
   04922 Glucagon signaling pathway
    100080392 (GNAS)
   04923 Regulation of lipolysis in adipocytes
    100080392 (GNAS)
   04912 GnRH signaling pathway
    100080392 (GNAS)
   04913 Ovarian steroidogenesis
    100080392 (GNAS)
   04915 Estrogen signaling pathway
    100080392 (GNAS)
   04921 Oxytocin signaling pathway
    100080392 (GNAS)
   04926 Relaxin signaling pathway
    100080392 (GNAS)
   04935 Growth hormone synthesis, secretion and action
    100080392 (GNAS)
   04918 Thyroid hormone synthesis
    100080392 (GNAS)
   04928 Parathyroid hormone synthesis, secretion and action
    100080392 (GNAS)
   04916 Melanogenesis
    100080392 (GNAS)
   04924 Renin secretion
    100080392 (GNAS)
   04925 Aldosterone synthesis and secretion
    100080392 (GNAS)
   04927 Cortisol synthesis and secretion
    100080392 (GNAS)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100080392 (GNAS)
   04270 Vascular smooth muscle contraction
    100080392 (GNAS)
  09154 Digestive system
   04970 Salivary secretion
    100080392 (GNAS)
   04971 Gastric acid secretion
    100080392 (GNAS)
   04972 Pancreatic secretion
    100080392 (GNAS)
   04976 Bile secretion
    100080392 (GNAS)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    100080392 (GNAS)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100080392 (GNAS)
  09156 Nervous system
   04724 Glutamatergic synapse
    100080392 (GNAS)
   04728 Dopaminergic synapse
    100080392 (GNAS)
   04726 Serotonergic synapse
    100080392 (GNAS)
   04730 Long-term depression
    100080392 (GNAS)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100080392 (GNAS)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100080392 (GNAS)
   04714 Thermogenesis
    100080392 (GNAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100080392 (GNAS)
   05207 Chemical carcinogenesis - receptor activation
    100080392 (GNAS)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    100080392 (GNAS)
   05165 Human papillomavirus infection
    100080392 (GNAS)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100080392 (GNAS)
   05142 Chagas disease
    100080392 (GNAS)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    100080392 (GNAS)
  09165 Substance dependence
   05030 Cocaine addiction
    100080392 (GNAS)
   05031 Amphetamine addiction
    100080392 (GNAS)
   05032 Morphine addiction
    100080392 (GNAS)
   05034 Alcoholism
    100080392 (GNAS)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100080392 (GNAS)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100080392 (GNAS)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100080392 (GNAS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oaa04147]
    100080392 (GNAS)
   04031 GTP-binding proteins [BR:oaa04031]
    100080392 (GNAS)
Exosome [BR:oaa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   100080392 (GNAS)
  Exosomal proteins of other body fluids (saliva and urine)
   100080392 (GNAS)
  Exosomal proteins of colorectal cancer cells
   100080392 (GNAS)
  Exosomal proteins of bladder cancer cells
   100080392 (GNAS)
GTP-binding proteins [BR:oaa04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    100080392 (GNAS)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA
Other DBs
NCBI-GeneID: 100080392
NCBI-ProteinID: XP_007669615
Ensembl: ENSOANG00000009275
LinkDB
Position
8:14052837..14178074
AA seq 174 aa
MFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNR
WLRTISVILFLNKQDLLADKVLAGKSKIEDYFPEFARYTTPDDATPEPGEDPRVTRAKYF
IRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
NT seq 525 nt   +upstreamnt  +downstreamnt
atgtttgatgttggagggcaacgagatgaacgcagaaaatggatccagtgtttcaatgat
gtgactgctatcatatttgtggtggccagcagtagctacaatatggttattcgagaggac
aatcagaccaatcggcttcaagaagcactaaacctcttcaagagtatttggaacaacagg
tggctacggaccatttcagtaatcctattcctgaataaacaggatttgttagcagataaa
gttttggcagggaaatctaaaattgaggactactttccagaatttgctcgctacactaca
ccagatgatgcaacacctgaacctggtgaggatcccagagttacaagggccaagtatttt
attagagatgaatttcttagaatcagcacagcaagtggagatggaaggcactattgctat
cctcacttcacatgtgcggtggatacagaaaatatccggagggttttcaatgactgtcgg
gacattattcagcggatgcaccttcgtcaatatgagttgttgtga

DBGET integrated database retrieval system