Ornithorhynchus anatinus (platypus): 100081118 Help Entry 100081118         CDS       T01045                                  Symbol ADCY6 Name (RefSeq) adenylate cyclase type 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism oaa  Ornithorhynchus anatinus (platypus) Pathway oaa00230   Purine metabolism oaa01100   Metabolic pathways oaa01522   Endocrine resistance oaa04015   Rap1 signaling pathway oaa04022   cGMP-PKG signaling pathway oaa04024   cAMP signaling pathway oaa04062   Chemokine signaling pathway oaa04072   Phospholipase D signaling pathway oaa04081   Hormone signaling oaa04082   Neuroactive ligand signaling oaa04114   Oocyte meiosis oaa04211   Longevity regulating pathway oaa04213   Longevity regulating pathway - multiple species oaa04261   Adrenergic signaling in cardiomyocytes oaa04270   Vascular smooth muscle contraction oaa04371   Apelin signaling pathway oaa04540   Gap junction oaa04611   Platelet activation oaa04713   Circadian entrainment oaa04714   Thermogenesis oaa04723   Retrograde endocannabinoid signaling oaa04724   Glutamatergic synapse oaa04725   Cholinergic synapse oaa04727   GABAergic synapse oaa04742   Taste transduction oaa04750   Inflammatory mediator regulation of TRP channels oaa04911   Insulin secretion oaa04912   GnRH signaling pathway oaa04913   Ovarian steroidogenesis oaa04914   Progesterone-mediated oocyte maturation oaa04915   Estrogen signaling pathway oaa04916   Melanogenesis oaa04918   Thyroid hormone synthesis oaa04921   Oxytocin signaling pathway oaa04923   Regulation of lipolysis in adipocytes oaa04924   Renin secretion oaa04925   Aldosterone synthesis and secretion oaa04926   Relaxin signaling pathway oaa04927   Cortisol synthesis and secretion oaa04928   Parathyroid hormone synthesis, secretion and action oaa04934   Cushing syndrome oaa04935   Growth hormone synthesis, secretion and action oaa04961   Endocrine and other factor-regulated calcium reabsorption oaa04962   Vasopressin-regulated water reabsorption oaa04970   Salivary secretion oaa04971   Gastric acid secretion oaa04972   Pancreatic secretion oaa04976   Bile secretion oaa05032   Morphine addiction oaa05163   Human cytomegalovirus infection oaa05166   Human T-cell leukemia virus 1 infection oaa05200   Pathways in cancer oaa05207   Chemical carcinogenesis - receptor activation oaa05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:oaa00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100081118 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100081118 (ADCY6)    04371 Apelin signaling pathway     100081118 (ADCY6)    04072 Phospholipase D signaling pathway     100081118 (ADCY6)    04024 cAMP signaling pathway     100081118 (ADCY6)    04022 cGMP-PKG signaling pathway     100081118 (ADCY6)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     100081118 (ADCY6)    04081 Hormone signaling     100081118 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100081118 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     100081118 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100081118 (ADCY6)    04062 Chemokine signaling pathway     100081118 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     100081118 (ADCY6)    04923 Regulation of lipolysis in adipocytes     100081118 (ADCY6)    04912 GnRH signaling pathway     100081118 (ADCY6)    04913 Ovarian steroidogenesis     100081118 (ADCY6)    04915 Estrogen signaling pathway     100081118 (ADCY6)    04914 Progesterone-mediated oocyte maturation     100081118 (ADCY6)    04921 Oxytocin signaling pathway     100081118 (ADCY6)    04926 Relaxin signaling pathway     100081118 (ADCY6)    04935 Growth hormone synthesis, secretion and action     100081118 (ADCY6)    04918 Thyroid hormone synthesis     100081118 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     100081118 (ADCY6)    04916 Melanogenesis     100081118 (ADCY6)    04924 Renin secretion     100081118 (ADCY6)    04925 Aldosterone synthesis and secretion     100081118 (ADCY6)    04927 Cortisol synthesis and secretion     100081118 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100081118 (ADCY6)    04270 Vascular smooth muscle contraction     100081118 (ADCY6)   09154 Digestive system    04970 Salivary secretion     100081118 (ADCY6)    04971 Gastric acid secretion     100081118 (ADCY6)    04972 Pancreatic secretion     100081118 (ADCY6)    04976 Bile secretion     100081118 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     100081118 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     100081118 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     100081118 (ADCY6)    04727 GABAergic synapse     100081118 (ADCY6)    04725 Cholinergic synapse     100081118 (ADCY6)    04723 Retrograde endocannabinoid signaling     100081118 (ADCY6)   09157 Sensory system    04742 Taste transduction     100081118 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     100081118 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     100081118 (ADCY6)    04213 Longevity regulating pathway - multiple species     100081118 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     100081118 (ADCY6)    04714 Thermogenesis     100081118 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100081118 (ADCY6)    05207 Chemical carcinogenesis - receptor activation     100081118 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100081118 (ADCY6)    05163 Human cytomegalovirus infection     100081118 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     100081118 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100081118 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100081118 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100081118 (ADCY6) Enzymes [BR:oaa01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100081118 (ADCY6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  100081118 NCBI-ProteinID:  XP_028929584 Ensembl:  ENSOANG00000008088 UniProt:  F6Z453 LinkDB All DBs Position 10:complement(54547867..54567105) Genome browser AA seq 1177 aa AA seqDB search MSWFRGLLVPKVDERKTAWGERNGQKSKRRGTGGLCGPRYMSCLQEPAPDAPRPGETSAR KGAGAGTAGPPGGTGPSGGTGHELGLKAVALGFEEGEGTGGEGAGGGAAAAGPGGVGGGA GWRRLARVFQSKQFESAKLERLYQRYFFQMNQSSLTLLMGVLVLAMGVLLAFHAAPAAPD PPYVAALAVAAALFLALMAVCTRRGFRPGCMGLVSYAVLALLGTVQGLGLLALAPRGASE GLWATVFFVYVAYTLLPVRMRAAVLSGLGLSALHLLLAWGLNREDAFLWKQLSANLLLFL CTNVIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVALEMKED ISAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAE NHCLRIKILGDCYYCVSGLPEPRADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHS GRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITQATLQYLNGDYEVEPGRGGE RNAYLKEHSIETFLILGASQKRKEEKAMLAKLQRARANSTDGLVPRWVPERSFPRTKDSK AFRQMGIDDSSKDNRSAQEALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQTKDL EKKYSRKVDSRFGGSVACTLLVFCFICLIQLLVVPRSALMLGLFGGIFLLLSGILLVCAA YSCLSLCPPALQRLSRNIVRSRARSTAVGVFSILLVFVSAFATMFSCDHTPVRSCAAKTL NLTPAAITACHLRRLNFSLGAEVPPCPGTAPACSFPEYFTESLLLSLLACSLFLHISSLG KLALVLAMGLLYLALLLLGPPAVLFDNYDLLLLAHALPAYNETQDGAECLAGEKLALKYM TPVILLVFALALYLHAQQVESTARLDFLWKLQATSEKEEMEELQAYNRRLLHNILPKDVA AHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDE IISEEPFRQLEKIKTIGSTYLAASGLNAATYDRAGRSHVTALADYAMRLMEQMKHINEHS FNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLA AKGYQLECRGVVKVKGKGEMTTYFLNGGPVSPTGSAS NT seq 3534 nt NT seq  +upstreamnt  +downstreamnt atgtcctggttccgcggcctcctggtgcccaaggtggacgagcggaagacggcttggggc gagcgcaacgggcagaagagcaagcggcggggcacgggcgggctgtgcggcccccgctac atgagctgcctccaggagcccgcgccggacgccccccggcccggcgagacctcggcccgg aagggggctggggcgggcaccgcgggaccaccgggcgggacggggccctccggcgggacg gggcacgaactgggcctcaaggcggtggccctgggcttcgaggagggcgaagggaccggt ggtgagggggccggcggcggggcggcggcggcggggccggggggcgtcgggggcggggcc ggctggcggcggctggcccgggtcttccagtcgaagcagttcgagtcggccaagctggaa cgcctgtaccagcgctacttcttccagatgaaccagagctccctgaccctgctcatgggc gtcttggtgctggccatgggcgtcctgctggccttccacgccgcgccggccgcccccgac ccgccctacgtggccgccctggccgtggcggccgccctgttcctggcgctcatggccgtg tgcacgcggcgcggcttccggcctggttgcatgggcctggtgagctacgcggtgttggcg ctgctgggcacggtccaggggctggggctgctggcgctggccccgcgtggggcctccgaa gggctctgggccaccgtcttcttcgtctacgtggcctacacgctgctccccgtccgcatg cgggccgccgtcctcagcggcctgggcctctccgccctgcacctcctcctcgcctggggc ctcaaccgcgaggacgccttcctctggaagcagctcagcgccaacctcctcctcttcctc tgcaccaacgtcatcggcatctgcacccactacccggccgaggtctcccagcgccaggcc ttccaggagacccgggggtacatccaggcccggctccacctccagcacgagaaccggcag caggagcgcctgctgctgtcggtgctgccccagcacgtggcgttggagatgaaggaggac atcagcgccaagcaggaggacatgatgtttcacaaaatctacatccagaagcacgacaac gtcagcatcctgtttgcggacatcgaggggttcaccagcctggcctcccagtgcactgcc caggagctcgtcatgaccctcaacgagctgttcgcccggttcgacaagctggccgccgag aaccactgtctgcggatcaagatcctgggagactgctactactgcgtgtccggcctgccc gagccgcgggctgaccacgcccactgctgtgtggagatgggcgttgacatgatcgaggcc atctcgctggtgcgagaggtgaccggcgtgaacgtgaatatgcgtgtgggcatccacagc ggccgtgtgcactgcggcgtgctcggcctccgcaagtggcagtttgacgtctggtccaac gacgtcacgctggccaaccacatggaggcgggaggccgcgccggccggatccacatcacg caggccacgctgcagtacctgaacggcgactacgaggtggagccgggccggggcggcgag cgcaacgcctacctgaaggagcacagcatcgagaccttcctcatcctcggcgccagccag aaacggaaggaggagaaggccatgttagccaagctgcagcgggcacgtgccaactcgacg gatgggctggtgccgcgttgggtgcccgagcgctcctttcctcgcactaaggactccaaa gccttccgccagatgggcatcgatgactccagcaaagacaaccgcagcgcccaggaggcc ctgaaccccgaggacgaggttgacgagttcctgggccgggccatcgacgcccgcagcatc gaccagctgcgcaaggaccacgtgcggcgcttcctgctcaccttccagaccaaagatctc gagaagaagtactcgcgaaaggtggactcacgctttgggggctccgtggcctgtacccta ctcgtcttctgcttcatctgcctcatccagctcctcgtcgttccgcgctcggccctgatg cttggtctcttcggaggcatcttcctcctgttgtctggcatcctgttggtctgtgccgcc tactcctgcctctctctgtgcccgcccgccctgcaacgcctctcccgcaacatcgtccgc tcccgggcccgcagcacagccgtcggcgtcttctccatcctgctcgtcttcgtctccgcc ttcgccaccatgttctcctgcgaccacacccccgtgcggagctgcgcggccaagacgttg aacctgacgcccgccgccatcaccgcctgccacctgcggagactcaacttctccctcggc gccgaggtcccgccctgcccgggcacggctcccgcctgcagcttccccgagtacttcacg gagagcctcctgctgagcctgctggcctgctccctcttcctgcacatcagcagcctgggc aagctggccctcgtgctggccatgggactgctctacctcgctctgctgctgctcggcccc ccggccgtgctcttcgacaactacgacctgttgctgctcgcccatgctctgccggcctac aacgagactcaggatggggcagagtgtttggcgggcgagaagctggcgctgaagtacatg acgcccgtgatcctgctggtgttcgcgctggcgctctacctgcacgcccagcaggtggaa tccacggcccgcctggacttcctctggaagctgcaggccacgagcgagaaggaggagatg gaggagctgcaggcttacaaccggcggctgcttcacaacatcctgcccaaggacgtggcg gcgcacttcctggcccgcgagcggcgcaacgacgagctgtactaccagtcctgcgagtgc gtggccgtcatgttcgcctccatcgccaacttctccgagttctacgtcgagctggaggcc aacaacgagggcgtcgagtgcctgcgtctgctcaacgagatcatcgccgactttgacgag atcatcagcgaggagcccttccggcagctggaaaagatcaagacgatcggcagcacgtac ctggcggcctcggggctgaacgcggccacgtatgaccgagccggccgctcccacgtcacc gcgctggccgactacgccatgcgcctcatggagcagatgaaacacatcaacgagcactcg ttcaacaacttccagatgaagatcggactgaacatgggcccggtggtggccggggtgatc ggagcccgcaagcctcagtacgacatctgggggaacacggtcaacgtgtccagtcgcatg gacagcaccggcgtccctgaccgcatccaggtgacgacggatctgtaccaggtgctggcg gctaagggctaccagctggagtgccgtggggtggtcaaggtgaagggcaagggcgagatg accacgtacttcctcaatgggggccccgtgagccccacggggtctgccagctag

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