KEGG   Ornithorhynchus anatinus (platypus): 100082297
Entry
100082297         CDS       T01045                                 
Symbol
PARP1
Name
(RefSeq) poly [ADP-ribose] polymerase 1
  KO
K24070  poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa03410  Base excision repair
oaa04064  NF-kappa B signaling pathway
oaa04210  Apoptosis
oaa04217  Necroptosis
oaa05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    100082297 (PARP1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    100082297 (PARP1)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    100082297 (PARP1)
   04217 Necroptosis
    100082297 (PARP1)
 09160 Human Diseases
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    100082297 (PARP1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:oaa03032]
    100082297 (PARP1)
   03036 Chromosome and associated proteins [BR:oaa03036]
    100082297 (PARP1)
   03400 DNA repair and recombination proteins [BR:oaa03400]
    100082297 (PARP1)
Enzymes [BR:oaa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.30  NAD+ ADP-ribosyltransferase
     100082297 (PARP1)
DNA replication proteins [BR:oaa03032]
 Eukaryotic type
  DNA Replication Termination Factors
   Other termination factors
    100082297 (PARP1)
Chromosome and associated proteins [BR:oaa03036]
 Eukaryotic type
  Centrosome formation proteins
   Centriole proteins
    100082297 (PARP1)
DNA repair and recombination proteins [BR:oaa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Other BER factors
     100082297 (PARP1)
SSDB
Motif
Pfam: PARP PARP_reg zf-PARP PADR1_N WGR Zn_ribbon_PADR1 BRCT BRCT_2 DUF948
Other DBs
NCBI-GeneID: 100082297
NCBI-ProteinID: XP_028902736
Ensembl: ENSOANG00000001488
LinkDB
Position
19:5419660..5452913
AA seq 1014 aa
MAEPADKLYRAEYAKSGRASCKKCGESIAKDSLRLAIMVQSPMFDGKVPHWHHFTCFWKR
ARVISHAEVDGFPELRWDDQEKIKKAIETGGAATGKGGDQDGGGGKGEKTLNDFAAEYAK
SNRSTCKGCDQKIEKGQVRLSKKMVDPVKPQLGMIDRWYHPDCFVSRRVELGFLPQYNAS
QLKGFGILKPEDKETLKKQLPAVKSEGKRKGDEVDGGGVVAKKKQKKEKDKETKQEKLLK
EQTELIWNIKDELKKACSTNDLKELLIANKQAVPSGETAILDRVADGMAFGALLPCEECK
GQFVFKSDAYYCSGDITAWTKCVAKTQTPNRKEWTIPKEFKEIPYLKKFKCKKQDRAFTP
EASTPVIVPLPSTTPAPPTLNSTVPADKPLSNMKILTLGKLSRNKEEMKATIEELGGKLT
GSANKASLCISTQKEVEKMNKKMEEVKEAGVRVVSEEFLKDVAASGKRLQELLTLHALSP
WGAEVKQEHPEVPLSGKSGGPVSTKSAGKIKEEEGASKSEKKMKLTVKGGAAVDPDSGLE
DSAHVFEKGGKIFSATLGLVDIVRGTNSYYKLQLLEDDREIRYWVFRSWGRVGTEIGSNK
LEQMPSKEDAIEHFLNLYEEKTGNSWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVSAG
TKSKLPKPVQNLIKMIFDVESMKKAMVEFEIDLQKMPLGKLSKRQIQNAYSILNEVQQAV
SEGGSDSQILDLSNRFYTLIPHDFGMKKPPLLNNMDCVQAKVEMLDNLLDIEVAYSLLRG
GSEDGDKDPIDVNYEKLKTDIKVVDKDSEEARIIREYVKNTHATTHNAYDLQVVDIFKIE
REGESQRYKPFKQLHNRQLLWHGSRATNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADM
VSKSANYCHTSQGDPIGLILLGEVALGNMYELKNASHISKLPKGKHSVKGLGKTAPDPSA
SITLDGVEVPLGTGISSGVSDTCLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW
NT seq 3045 nt   +upstreamnt  +downstreamnt
atggcggagcccgccgacaagctctaccgggccgagtacgccaagagcggccgcgcctcc
tgcaagaaatgcggcgagagcatcgccaaggattcgctgcggctggccatcatggtgcag
tcacccatgttcgatgggaaggtcccacactggcaccattttacttgtttctggaagcgg
gcacgggtcatctcccatgccgaggtggatggtttccccgaattgcggtgggatgaccag
gagaagatcaagaaagccatagagactggaggagccgccacaggtaaaggtggagaccag
gatggcggaggaggcaagggggagaagaccctgaatgactttgcagctgaatatgccaag
tctaacaggagcacgtgcaagggatgtgaccagaaaatcgaaaagggccaggtacggctc
tccaagaagatggtggatccagtgaagccacagttggggatgattgaccgctggtaccat
ccggactgcttcgtcagccgccgagttgagcttggctttctcccgcagtataacgccagc
cagctcaaagggtttggtatcctgaagccagaggacaaggaaaccctgaagaagcagctc
cctgccgtcaagagcgaagggaagaggaaaggagatgaggtggatggaggtggcgtggtg
gccaagaagaaacagaaaaaggaaaaagacaaggaaaccaagcaggagaagctgctcaag
gagcagacagagttgatctggaacatcaaagatgagctgaagaaagcctgctccacgaac
gacttgaaagagctgcttatagccaacaagcaagccgtgccttctggggagacggcgatt
ttggatagagtggccgatggaatggcctttggagcacttcttccctgcgaggagtgcaaa
gggcagttcgtcttcaagagcgatgcctactattgctccggggacatcacggcctggacc
aaatgtgtggccaagacccagacgcccaacaggaaggaatggaccatcccgaaggagttc
aaggaaatcccgtacctaaagaaatttaagtgcaaaaagcaggaccgagccttcacccca
gaggccagcacccctgtgatcgtgcctttgccctcaacgacccctgctccccccacgctg
aactcgactgtgccggcagataagccgttgtccaacatgaagatactgactcttgggaag
ctttccagaaacaaagaagagatgaaggccacgattgaggagctcggggggaaattgacg
ggttccgccaacaaggcctccctgtgcatcagtactcaaaaggaagtggagaagatgaac
aagaaaatggaggaggtgaaggaggctggagtgcgggtggtttctgaggagttcctcaag
gatgttgccgcctcgggcaagaggctccaggagctgctgaccctgcacgccttgtcaccc
tggggggctgaggtgaagcaagagcaccccgaggtgccactgagcgggaagtcaggcggc
cctgtctccaccaagagtgcgggcaagatcaaggaggaggaaggagccagcaagtccgaa
aagaagatgaagttaaccgtaaaaggaggcgcagctgtcgatccggattctggcttggag
gactcggctcacgtctttgaaaagggcgggaaaatcttcagcgccaccctcggcctggtg
gacatcgtccgaggaaccaattcatattataaactgcagctcctggaggatgaccgagaa
atcaggtactgggtgtttagatcctggggccgcgtgggcactgagattggcagtaacaag
ctggagcagatgccatccaaagaagatgccattgaacactttctgaacttgtatgaagag
aaaaccggcaactcctggcattccaagaactttactaaatatcccaaaaaattctatcct
ctagaaatcgattatgggcaggatgaggaggcagtgaagaaactgactgtcagcgccggc
accaagtccaagctccctaagcccgttcagaacctcatcaagatgatctttgacgtggag
agcatgaagaaggccatggtggaattcgagattgacctccagaagatgccactgggaaag
ctaagtaagaggcagatccagaacgcttactctatcctgaacgaggtccagcaggccgtg
tctgagggaggcagcgactctcagatcctggacctgtccaaccgcttctacacactgatc
ccccacgactttgggatgaaaaagcctccgcttctgaacaacatggactgtgtgcaggcc
aaggtagagatgttggacaacctgctggacatcgaggtggcctatagcctgctccggggt
ggctctgaagatggtgacaaggaccccatcgatgtcaactatgagaagctcaaaacggac
atcaaggtggttgacaaagactcagaagaagccagaatcattagggagtacgtcaagaac
actcatgccacaacacacaatgcttatgacctgcaagttgttgatatcttcaaaattgag
cgggaaggagagagtcagcgctataagccattcaagcagcttcacaaccggcagctgctc
tggcacggttcccgggctacaaactttgctggtatcctgtcccaaggcctgcgaatcgcc
ccccctgaggctcccgtgaccggctacatgtttggaaaaggcatctacttcgcggacatg
gtctccaagagtgccaactactgccacacatctcagggagatcctatcggcttgatcctg
ctgggagaagtggccctcggaaacatgtatgagctgaagaacgcatcccatatcagcaag
ctgcccaaagggaagcacagcgtcaaaggtttgggcaaaactgcccctgatcccagtgcc
agcatcaccctcgatggggtggaggttcccctggggactgggatttcgtcgggggtcagc
gacacttgcctactgtataacgaatacatcgtctatgatattgctcaggtaaatctgaag
tatctgctgaaactgaagttcaactttaagacgtcgctgtggtga

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