Ornithorhynchus anatinus (platypus): 100083317
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Entry
100083317 CDS
T01045
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa00230
Purine metabolism
oaa00670
One carbon pool by folate
oaa01100
Metabolic pathways
oaa01523
Antifolate resistance
Module
oaa_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100083317 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100083317 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100083317 (GART)
Enzymes [BR:
oaa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
100083317 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
100083317 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
100083317 (GART)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_3
CPSase_L_D2
ATP-grasp_2
Dala_Dala_lig_C
ATP-grasp_4
Motif
Other DBs
NCBI-GeneID:
100083317
NCBI-ProteinID:
XP_028937723
Ensembl:
ENSOANG00000002432
UniProt:
F7AHM6
LinkDB
All DBs
Position
17:complement(20532114..20554231)
Genome browser
AA seq
1008 aa
AA seq
DB search
MSSRVLVIGNGGREHALAWKLAQSQRVKHVLVAPGNAGTASLEKISNAAISVNDHTELAQ
FCKDQEIELVVVGPEAPLAAGIVGDLTAAGVRCFGPTAEAAQLEASKRFAKEFMDRHGVP
TARWKAFTDSQEACDFISSADFPALVVKASGLAAGKGVIVATNKEEACKAVQEIMQDRAF
GGAGETVVIEELLEGEEVSCLCFSDGKTVAPMLPAQDHKRLMDGDKGPNTGGMGAYCPAP
QVSKDLFLTIKNTILQKTVEGMQQEGTPYVGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDFYEVIQSALDGQLSAHVPEWLDDSAAVTVVIASRGYPGSYAKGLEITGFPEA
KTLGLEVFHAGTTLKEGRVVTNGGRVLMVTAIRKDLVSALETANKGLAAIKFEGAIFRKD
IGYRAIAFLKQSRGLTYKESGVDIEAGNALVKKIKPLAKATSRSGCSVDLGGFAGLFDLK
LAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDIDTAGAVITGIAEACRKAGCALLGGETAEMPGMYPPGEYDLGGFAVGAMERDQKLP
RLESIVAGDVVIGVASSGLHSNGFSLVRKIVEASSLHLSSPAPSGCGNQTLGELLLTPTR
IYCRTLLPVLHSGRVKALAHITGGGLLENIPRVLPDKLGVRLDARGWQVPAIFSWLQYQG
RLSEEEMARTFNCGVGAVLVVQKDLAQQVLQEVKQHEEEAWIIGRVVTCPAGSPRVQVDH
LVEAMQVNRSCSLTNGSLHSHLHDQPKKARVAVLISGTGTNLQALITSTKEPTSSAQIVL
VISNKAAVLGLERAEKAGIPTRVIDHKLYKTRAEFDSTVDKVLEEFSVELVCLAGFMRIL
SGPFVKKWDGKMLNIHPSLLPSFKGSNAHEQALEAGVRITGCTVHFVAEEVDAGQIILQE
AVPVKRGDTVATLSERVKEAEHRAFPAALQLVASGEVQLGPTGKIVWN
NT seq
3027 nt
NT seq
+upstream
nt +downstream
nt
atgtcttcccgagtgcttgtgattggcaatggagggagagaacatgcgctggcctggaaa
ctggcccagtctcagcgtgtcaaacacgtattggtcgctccaggaaacgcaggaacagca
agtcttgagaagatttcaaatgcagctatctcagtcaacgatcacactgaactcgctcag
ttctgcaaggaccaggagattgaacttgtagtcgttggtccagaagctcctcttgctgcc
gggatcgtgggagatctgacagcggctggggtgagatgcttcgggcccacggcggaggca
gctcagctggaggccagcaaaaggttcgccaaggagtttatggaccggcacggggtcccg
accgcgagatggaaggcgttcaccgattctcaggaggcctgcgacttcatcagcagtgca
gactttcccgccctggttgtcaaggccagtggtctagctgccggaaagggagtgattgta
gctacaaacaaagaagaagcctgcaaagcagttcaagagatcatgcaggatagggctttt
ggcggtgctggagaaactgttgttatagaagaactcttagaaggagaagaggtgtcgtgt
ttgtgcttcagcgatggtaaaaccgtggcccccatgctgcctgcacaggaccacaagcgc
ctgatggatggagacaaaggcccaaatactggtgggatgggagcttattgccccgcgcct
caggtttccaaggatttatttttgacaatcaagaacacaattcttcagaaaacagtggaa
ggcatgcagcaagagggtactccatatgtgggagtgctctatgccggaatcatgcttacc
aaagatggcccaaaagttctggagtttaattgcagatttggggatccagaatgccaggtt
atcctcccccttctcaaaagcgatttttatgaagtgatccagtccgctttggacggccag
ctcagcgcccacgtgcccgagtggctagatgacagcgccgcggtgaccgtcgtcattgca
agccggggctatcccggcagttacgccaagggcttggagataacaggcttcccagaggca
aaaactttagggctggaggtgttccacgcaggcacgaccctgaaagaagggagagtggtc
actaacggaggcagagtcctgatggtgactgccatccggaaagacctggtgtccgccctt
gagacggccaataaaggacttgcagcgatcaagtttgagggggccatttttaggaaagac
attggttatcgagcgatagctttcctcaagcagtccagaggcctgacgtataaggaaagt
ggagtggacattgaggctggcaatgcactggttaagaagattaaacctttggcaaaagcc
acctccagatcaggctgcagtgtagatctcggaggatttgccggtctctttgatttgaaa
ctagctggtttcaaagatcctctcctagcatcggggacagatggcgtcggaaccaaactg
aagatcgcacagctgtgtaacaagcacgacaccatcggtcaagatttggtggctatgtgt
gtcaatgacattctggcccagggggcagaacccctcttcttccttgactacttttcctgt
ggaaaactggacattgacacagcaggtgccgtcatcactggaatagcagaagcgtgtcgg
aaggcaggctgtgctcttctgggaggcgagacggccgagatgcccgggatgtatcctcca
ggggaatatgacctgggaggctttgctgtcggagccatggagcgggaccagaagcttcct
cgcttagagagcatcgtcgccggggacgtcgtcatcggagtggcttcctccgggcttcac
agcaacgggttcagcctcgtgaggaaaattgtggaggcgtcttccctccacctctcctcc
ccggctcctagtggatgtgggaaccagactctgggggagctgctgctgaccccgacccgg
atctactgccgtacgctgttaccggtcctgcattcaggacgcgtcaaggccctggcccac
atcactggaggggggctgctggaaaacatccccagggtcctccctgacaagctgggagtg
cggttggatgcgcgtggctggcaagtccccgccatcttctcgtggctgcagtaccaggga
cgcctctcggaagaagagatggctcggaccttcaactgcggcgtgggagccgtcctcgtg
gtccagaaggacctggcgcagcaggtgttgcaggaggttaaacagcacgaggaggaggcc
tggatcattggcagagtggtcacttgtcctgcaggttctccccgcgtccaggtcgatcat
ttggttgaagccatgcaagtaaacaggtcgtgttcattgacaaatggttccttacacagc
cacctgcatgaccagccgaaaaaggcaagggtggccgtcctgatatctggaacgggtacc
aacctacaagcgctaataaccagtaccaaggaaccaaccagctctgcacaaatagtcctt
gtcatctctaacaaagcagctgtgcttgggctagagagggcagagaaggctggtattcct
accagagtcatcgatcacaagttgtataagacccgcgccgagtttgacagcacagttgac
aaagtcttggaagagttctctgttgagctggtctgtctcgcaggcttcatgagaatcctg
tctggcccctttgtcaaaaagtgggatgggaaaatgctgaacatccacccttccttgctc
ccatctttcaagggttcaaatgcccacgaacaggccctcgaagctggagtcagaatcacc
ggctgcaccgtgcactttgtagccgaagaagtagatgctggacagatcatccttcaagag
gctgtccccgtaaagaggggtgacacggtggctaccttgtcggaacgagtcaaagaggcg
gaacacagagcttttcctgccgccctacagcttgtggcaagtggagaagtacagctgggg
ccaacaggcaagattgtttggaattaa
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