Ornithorhynchus anatinus (platypus): 100083336
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Entry
100083336 CDS
T01045
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa00230
Purine metabolism
oaa00670
One carbon pool by folate
oaa01100
Metabolic pathways
oaa01523
Antifolate resistance
Module
oaa_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100083336
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100083336
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100083336
Enzymes [BR:
oaa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
100083336
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
100083336
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
100083336
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GARS_A
AIRS_C
Formyl_trans_N
GARS_N
GARS_C
AIRS
Motif
Other DBs
NCBI-GeneID:
100083336
NCBI-ProteinID:
XP_039770489
Ensembl:
ENSOANG00000002431
LinkDB
All DBs
Position
17:20507866..20531603
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AA seq
1064 aa
AA seq
DB search
MSARVLVIGNGGREHTLAWKLAQSPHVKQVLVAPGNAGTADAGKITNSAVLASNHTILAQ
FCKDHNIGLVVVGSGSLLAAGIVDDLTAAGVRCFGPTAKAARLEASKKFAKEFMDRHGIP
TARWKAFTDSHEACDFIVGTEFPALVVKTGGPCARDARVIVAASREEACQVARELMQSDV
FGESEGVVMVEELLKGEEISCFCFSDGVASVAMPIARSQRRLLDGDLGPITGGMGAYCPA
PKISEEVLKELRGGFLQHIIDSMKREGAAYIGILQVGIMLTESGMKVLNFKCCFSDPECQ
VILPLLQNDLYDVIQATLDGRLRARVPVWREDRAAVALVLASEGYPGDHVKGSEITGLLE
PRGPGLEVFHSSTALRDGTVVTDGGRVLVVTAVGEDLASALAGAREASSAIRFPGATFRR
DIGRPAADGTEGLREITPSWKAPGKQISLNPTYDNSVLSLSVGDSQGHSGQEQSSGHTKE
WQLSFNTNCKRTLERKPNNTSDGQTEPRDEVLAGVFELKAAGYQSPVLVSRTRSIGPKIK
IAQLCNKHDTIGHDVVAACVNDVLAQGAEPLFFLCHLTQGKLGVRIREEIHVGLREACEV
AGCKLLGGEMSEEPGTHSPGEFEPVGFAVGAVERGQLLPQTESIVAGDVVIGVASSGLHC
SGFGLVRKLVEVSSLCLSSPAPSACRGQTLGQLLLTPTRIYCRPLLPVLRSGRVKALAHI
TGGGLLENIPRVLPDKLGVQLDARRWRIPTVFSWLQYQGRLSEDEMARNFNCGIGAILVV
QEDLAEQVLREVQRHEEEAWLIGSVVPRHEGASRFEVKNLSTALRTGHGQVREATALEES
PLQDRPPKSKVRVAVLLSGAGPGLGALIALGKEPACCVQTALVISNKPGVRELREAALAG
IPTRVIDHTLFGSRKEFDGTIDKVLKEFSIEVVGLAGFTRILSGPFLRKWNGKILDIYPS
LSPSVQGRNVRNQERQAGDKLPGCTVRFLLEEAGTGAVILQEPVKVEAGDTEEALSIRVK
ETAGRAFPFALQLVASGAVRLGGDGKVSWEQGVLRQLPHLEKSS
NT seq
3195 nt
NT seq
+upstream
nt +downstream
nt
atgtcagcccgggtgcttgtgattggaaatgggggcagagagcacactctcgcttggaag
ctggcccagtcacctcatgtcaagcaagtattggtcgccccagggaacgctggaacagcc
gatgctgggaaaatcaccaattcagctgtgttggccagcaaccacaccatcctggcacag
ttctgcaaagaccataacataggacttgtagtcgttggatcagggtcccttcttgctgct
gggattgtggatgacctgacggcagctggggtgagatgtttcgggcccactgcgaaggca
gcgcggctggaggccagcaaaaagttcgctaaggagtttatggaccggcacgggatcccg
actgcccggtggaaagcgttcaccgactcgcacgaggcctgcgatttcatcgtgggcacc
gaattccctgccctggtggtgaagaccggcggcccgtgtgccagagatgcccgggtcatc
gtggctgctagtagagaagaggcctgccaggtagcacgggagctgatgcagagtgatgtc
tttggagaatctgaaggagtagtgatggttgaagaacttcttaaaggagaagagatatct
tgcttctgcttcagtgacggtgtggctagcgtcgccatgccgatagctcggagccagaga
cggctactggatggagacctgggcccgatcaccggggggatgggagcttactgcccggcc
cctaagatttctgaagaggttctaaaggagctcagaggtggttttcttcaacacattatt
gacagcatgaagcgagaaggtgcagcatatataggcatactgcaagtgggaataatgctt
acggaaagtgggatgaaggtgctaaacttcaaatgctgcttcagtgaccccgagtgccag
gtaatcctgccccttctccaaaacgacctctacgacgtgatccaggccaccctggatggg
cggctccgcgcccgcgtgccagtgtggcgggaagaccgagcggcggtggctctcgtccta
gccagcgaaggttatccgggagatcacgtcaagggctcggagataaccggccttcttgag
cctcgaggtccgggcctggaggtgttccactccagtacggccctgagggacgggaccgtg
gtgacggacggtggcagagtcctcgtggtcacggccgtcggcgaggacctggcgtcggcc
ctggcgggagccagggaggcgtcatcggccatccgcttcccgggagccactttccgccgg
gatataggccggccggctgcggatggaacggagggccttagggagatcaccccttcttgg
aaggctcctggcaaacagatctcactgaaccccacctatgacaactccgtgctgagtttg
agtgtcggggacagccagggacattcagggcaagagcagagctctgggcacactaaagag
tggcaactcagcttcaacaccaactgcaagcggaccctggaaagaaaaccaaataacacc
tcagatgggcagacagaaccccgggatgaggtccttgcgggagtcttcgagctgaaggcg
gctggttaccaaagccccgtcctggtctcaagaaccagaagtattgggccgaagatcaag
attgcccagctgtgtaataaacacgacaccataggtcacgatgtggtggccgcgtgtgtc
aacgatgttctggcccagggagcagagcccctcttcttcctctgccatctgacccaagga
aagcttggggtgagaatcagggaagagatccacgttggcctcagagaagcctgtgaagtg
gcaggctgcaaactcctgggaggtgaaatgtctgaagagcctggcacccactcacctggg
gagtttgagccggtgggttttgccgtgggagccgtggaacgcggtcagctgcttccccag
acagagagcatcgttgccggggacgtggtcatcggagtggcttcttccgggcttcactgc
agtgggttcggcctcgtgaggaagcttgtggaggtgtcgtccctctgcctctcctccccg
gcccctagtgcatgtcggggccagactctggggcagctgctgctgaccccgacccgaatc
tactgccgcccgctgctaccagtcctgcgttcaggacgcgtcaaggctctggcccacatc
actggagggggactgctggaaaacatccccagggtcctccctgacaagctgggggttcag
ttggatgctcgacgctggcggatccccaccgtcttctcatggctgcagtaccaggggcgc
ctctcggaagacgagatggctcggaactttaactgcggcatcggggccatcctcgtggtc
caggaggacctggcggagcaggtgctgcgggaagttcaacggcacgaggaggaggcctgg
ctcattggcagcgtggtgccccgccatgaaggtgcttctcggttcgaggtcaagaatctg
tcaactgctttgaggacaggccacggtcaggtgagggaggccacagccctggaagaatcc
cctctccaggacaggcccccaaagtccaaagtcagagtggctgttcttctctctggagca
ggcccaggtcttggagccctgattgctctggggaaggagcctgcctgctgtgtccagacg
gccctggtcatctccaataagcccggcgtgcgagagctccgagaggcagccctagcgggg
atcccaacaagagtcatcgatcatacgttgttcggaagccgcaaagaattcgacggcacc
atcgacaaggtcctgaaagaattctccattgaggtggttggtctggctggattcacgagg
attttgtcggggcctttcctcagaaagtggaatggaaagattttagacatctatccatcg
ctttcgccatcagtccaagggaggaacgtccgcaaccaagagcgtcaagctggggacaag
ctcccaggctgtaccgtccgctttcttctcgaagaagccggcaccggagctgtcatcctg
caggagccggtcaaggtggaggcgggagacaccgaagaggctttgtctatacgagtgaag
gaaacagcgggccgggccttccccttcgccctgcagctggtggccagcggggccgtgcga
ttgggaggggacggaaaagtctcttgggagcaaggggttctaaggcagctgcctcacctg
gagaaaagttcctga
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