Ornithorhynchus anatinus (platypus): 100083539
Help
Entry
100083539 CDS
T01045
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa00010
Glycolysis / Gluconeogenesis
oaa00020
Citrate cycle (TCA cycle)
oaa00620
Pyruvate metabolism
oaa00785
Lipoic acid metabolism
oaa01100
Metabolic pathways
oaa01200
Carbon metabolism
oaa01210
2-Oxocarboxylic acid metabolism
oaa04066
HIF-1 signaling pathway
oaa04922
Glucagon signaling pathway
oaa05230
Central carbon metabolism in cancer
oaa05415
Diabetic cardiomyopathy
Module
oaa_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100083539 (PDHA1)
00020 Citrate cycle (TCA cycle)
100083539 (PDHA1)
00620 Pyruvate metabolism
100083539 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100083539 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100083539 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100083539 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100083539 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100083539 (PDHA1)
Enzymes [BR:
oaa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100083539 (PDHA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
100083539
NCBI-ProteinID:
XP_028935575
Ensembl:
ENSOANG00000004029
UniProt:
F6ZAF4
LinkDB
All DBs
Position
15:complement(16956453..16970584)
Genome browser
AA seq
395 aa
AA seq
DB search
MRKMLAALSRLLPGAAHTPGAAIEAGRVLVASRNFANDATFDIKKCDLHRLEEGPPVTTV
LTREEGLKYYRTMQTIRRMELKADQLYKQKIIRGFCHLYDGQEACCVGLEAGINPTDHVI
TAYRAHGYTYTRGLAVREILAELTGRKGGCAKGKGGSMHMYANNFYGGNGIVGAQVPLGA
GIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVER
AAASTDYYKRGDYIPGIRVDGMDILCVREATKFAAAHCRSGKGPMLMELQTYRYHGHSMS
DPGVSYRTREEIQEVRSKSDPITLLKDRMVNNNLTTVEELKEIDVEVRKEIEDAAQFATT
DPEPPLEELGYHIYSREPPFEVRGPNQWIKYKSVS
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
atgcggaagatgctggccgcgctcagccgtctgctgcccggcgccgcacacactccggga
gctgctattgaggccggaagagtgctggtagcatctcgaaacttcgccaacgatgccacg
tttgatatcaagaaatgtgatcttcatcgcttggaagaaggccctccggtcaccacggtg
ctcaccagagaggaggggctcaaatactacaggacaatgcagactatccgtcggatggaa
ttaaaggcagaccagttatataagcagaagatcatccgtggcttctgtcacctgtatgac
ggacaggaagcatgttgtgttgggcttgaggcggggatcaaccccacggaccacgtgatc
accgcctatcgggcgcatggctacacttacacccgtgggctggctgtccgggagatcctg
gcagagttgacaggtcgaaaaggcggctgtgctaaagggaaaggaggatcgatgcatatg
tacgccaataatttttacggggggaatggcatcgtcggagctcaggtgcccctgggggct
ggtattgccctggcctgtaaatacaatggcaaagatgaggtctgtttgactctctatgga
gatggtgctgctaatcagggtcagatatttgaagcgtacaatatggccgctctgtggaaa
ctgccatgcattttcatctgcgagaacaaccgttatggaatgggcacgtcggtcgagaga
gctgcagccagcaccgactactacaaaagaggagattacattccggggataagggtagac
ggtatggatattctctgtgtccgtgaagcaacaaagttcgctgctgcccactgtagatct
ggaaagggtcctatgttgatggaacttcagacctatcgttaccatggacacagcatgagt
gaccctggagtcagttaccgaactagggaagagattcaagaagtgcggagtaagagcgat
cccattacactcctgaaggataggatggtcaacaacaacctcactaccgttgaagagctg
aaggagattgacgttgaagtaaggaaggagatagaggatgcggcccagtttgccacaacg
gatcccgagccgcccctggaagaactgggctaccacatctactcccgcgagccgcctttt
gaagttcgtggcccgaaccagtggatcaagtacaagtctgtaagctag
DBGET
integrated database retrieval system
